Doctoral students Swiger, Freeman earn TSNRP honor
Six from UAB School of Nursing named Academy Fellows
Cherven, Wells chosen 2016 RWJF Future of Nursing Scholars
Dr. Ann Gakumo attends 2016 Butler-Williams Scholars Program
Congratulations to Dr. Wilbanks - Our newest PhD Graduate!
Dionne-Odom films video for American Society of Clinical Oncology
Professor David Vance awarded five-year, $2.86-million grant by NIMH

Fatigue, sleep-wake disturbances, and quality of life in adolescents receiving chemotherapy.

Erickson JM, Beck SL, Christian BR, Dudley W, Hollen PJ, Albritton KA, Sennett M, Dillon RL, Godder K.

University of Virginia, Charlottesville, VA, USA. jme3a@virginia.edu

Abstract

BACKGROUND:

Adolescents with cancer experience distressing physical and psychosocial symptoms, especially during treatment. Fatigue and sleep disturbances commonly affect adolescents' quality of life, but little is known about how adolescents experience these symptoms during an early month of chemotherapy. This study measured fatigue, sleep disturbances, and quality of life in 20 adolescents over 1 month while they were receiving chemotherapy.

METHODS:

Multidimensional fatigue and quality of life were measured weekly with modules from the PedsQL Measurement Model, and sleep disturbances were measured with the General Sleep Disturbance Scale.

RESULTS:

Adolescents experienced increased severity of fatigue and sleep disturbances during the week after treatment. Common sleep-wake problems included daytime sleepiness, decreased alertness, and poor sleep quality. Fatigue and sleep-wake disturbances were related symptoms, and both symptoms were associated with various domains of quality of life.

CONCLUSIONS:

Fatigue and sleep-wake disturbances are significant problems for adolescents receiving chemotherapy and negatively affect the quality of life. Clinicians should routinely screen adolescent patients for fatigue and sleep disturbances and intervene to minimize their impact using pharmacologic and nonpharmacologic strategies.


 Link to PubMed