A systematic review of probiotics as a potential intervention to restore gut health in HIV infection
Wilson, N.J., Moneyham, L., Alexandrov, A.W.
Probioticshave beneficial effects on thegutin numerous conditions. The purpose of this paper is to present areviewof the current literature onprobioticsused in chronic illnesses exhibiting similar pathology seen inHIVgutdysfunction, in order to make recommendations for their use to promote andrestorehealing of thegutwith subsequent reduction of ongoing inflammation caused by microbial translocation. Areviewof the literature was performed, focusing onprobioticsas aninterventionto improveguthealth. Key words were searched in PubMed and the Cumulative Index to Nursing and AlliedHealthLiterature. The literature reviewed was limited to clinical trials, meta-analyses, and practice guidelines. Thereviewprovided evidence thatprobioticswere supportive in modulating aspects ofgutphysiology, barrier integrity, and immune function. Probiotic use is a supportive adjunct therapy, worthy of consideration and further research in persons infected withHIV.
Copyright © 2013 Association of Nurses in AIDS Care. Published by Elsevier Inc. All rights reserved.