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Specifically, depression has been recognized as a strong predictor of HIV care non-adherence, and consequently of increased morbidity and mortality. HIV-infected women are disproportionally affected by depression in comparison to HIV-infected men. However, interventions addressing the psychosocial needs of HIV-infected women, particularly in the rural Deep South of the United States where HIV prevalence remains high, are limited.

The findings from this project will provide a framework that will inform a theory-based intervention to improve depression and adherence to HIV care.
Dr. Kempf and her investigative team have applied for extramural funding to pilot the intervention among HIV-infected women located in Alabama, followed by a multi-site randomized controlled trial of the intervention in other areas within and outside the state.

The long-term goal of the larger project is to develop an effective intervention that significantly improves clinical outcomes in HIV-infected women by decreasing depression morbidity and simultaneously increasing both adherence to antiretroviral therapy (ART) and retention in care.

For more information, please contact Dr. Kempf at mkempf@uab.edu