Michael R. Frost, Ph.D.

FrostMichael R. Frost, Ph.D.
Research Instructor, Vision Sciences

Contact Information:
mrf@uab.edu
Office – 205.934.6733








Physical Address:
306 Worrell Building
924 18th Street South
Birmingham, AL 35294-4390

Mailing Address:
WORB 306
1720 2nd Avenue South
Birmingham, AL 35294-4390

Education:
B.Sc. (Hons) – The University of Dundee; Dundee, Scotland, UK.
Ph.D. – The University of Wales; Cardiff, Wales, UK.
Postdoctoral – The Hong Kong Polytechnic University; Hong Kong.

Secondary Appointments:
UAB Graduate School

Faculty Scientist, Vision Science Research Center

Scholarly Activity:
Research – During postnatal development of the eye, there appears to be a vision-dependent mechanism that controls the rate of axial elongation of the eyeball to match the eye’s optical power. This emmetropization mechanism should result in eyes without refractive error. If the emmetropization mechanism is disrupted, the result is an eye that is either too long (myopia) or too short (hyperopia) for its optics, producing blurred vision. Current research is focused on two aspects of the emmetropization mechanism: the visual conditions that increase and decrease the rate of eye elongation, and the biomechanical, biochemical, and molecular changes that underlie this altered elongation rate. Understanding the mechanism underlying emmetropization may lead to optical, pharmacological, or (possibly) gene therapy treatments to slow axial elongation and, ultimately, myopia development in children.

Publications:

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