I13005—Immunology/ Rheumatology

Contact:

Mentor/Principal InvestigatorRobert P. Kimberly, M.D. Professor  Mailing address: SHEL 176, 1530 3RD AVENUE S BIRMINGHAM AL 35294-2182  Telephone: (205) 934-0245  E-mail: rpk@uab.edu


Immunogenetics and Functional Genomics

Research opportunities are available in cellular and molecular immunology, emphasizing genetic variation of immune response genes and the impact on immune system function, including the predisposition to autoimmune and immune-mediated inflammatory diseases and the characteristics of host responses to infectious agents. Both human and non-human model systems form the basis for study.

The primary emphasis of the program is the identification and understanding of naturally occurring, genomically encoded variants of immune response genes. Mentors are involved in both their own research programs and in the care of patients with autoimmune and immune-mediated inflammatory diseases, thus providing an opportunity for translational work between model systems and human immunology. Opportunities in human biology and disease are available in autoimmune and immune-mediated inflammatory diseases, malignant diseases, host-defense defense including vaccine development, and transplantation immunology. Outstanding investigator-based and core-based facilities are available. Resources include state-of-the-art high-speed flow cytometry, high resolution imaging (confocal, FRET, standard and cryo-election microscopy), nucleic acid and protein sequencing, hybridoma/phage display antibody production, and transgenic/ES cell mouse facilities.

Postdoctoral trainees with an M.D., Ph.D. or equivalent terminal degree are selected on the basis of prior academic and research performance, letters of recommendation, and personal interviews. Successful candidates will demonstrate a strong commitment to a research and teaching career in investigative biomedical sciences. For further information, please contact Dr. Robert Kimberly, E-mail: rpk@uab.edu.

Postdocs in UAB News

  • Increased risk of major adverse cardiac events after the later surgery persists for one year.Carla HolcombA patient who has noncardiac surgery sometime after a stent is put into a coronary artery to open up a blockage has a greater risk for major adverse cardiac events (MACE) following the operation, but the optimal time to delay such elective surgery after stenting was not known. In a study of more than 28,000 patient records, first author Carla Holcomb,...

  • UAB School of Public Health research published in the journal Obesity shows seeing, hearing and smelling others’ eating foods can cause low birthweight in offspring among mice.While studies have shown that what a mother eats during pregnancy can affect her offspring, it could be that what she sees others eating can also affect her offspring. New research from the University of Alabama at Birmingham School of Public Health explores the influence it has in a...

UAB Research News

  • Pioneering cancer research at UAB will be presented at the American Society of Clinical Oncology meeting.A team of physician-scientists and researchers from the UAB Comprehensive Cancer Center will present some of the latest advances in cancer research to more than 25,000 oncology professionals during the 51st annual meeting of the American Society of Clinical Oncologyin Chicago May 29-June 2, 2015.  UAB Cancer Center investigators are authors on more than 50 abstracts accepted by ASCO for the...

  • Two children die each day in the United States as a result of poisoning. UAB child safety expert David Schwebel, Ph.D., works to prevent this from occurring.Click to enlargeThe summer months often mean more time spent at home for kids. While the break from the books can be enjoyable, one University of Alabama at Birmingham child safety expert says there is one important lesson both children and parents still need to learn: how to prevent...