I13005—Immunology/ Rheumatology

Contact:

Mentor/Principal InvestigatorRobert P. Kimberly, M.D. Professor  Mailing address: SHEL 176, 1530 3RD AVENUE S BIRMINGHAM AL 35294-2182  Telephone: (205) 934-0245  E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.


Immunogenetics and Functional Genomics

Research opportunities are available in cellular and molecular immunology, emphasizing genetic variation of immune response genes and the impact on immune system function, including the predisposition to autoimmune and immune-mediated inflammatory diseases and the characteristics of host responses to infectious agents. Both human and non-human model systems form the basis for study.

The primary emphasis of the program is the identification and understanding of naturally occurring, genomically encoded variants of immune response genes. Mentors are involved in both their own research programs and in the care of patients with autoimmune and immune-mediated inflammatory diseases, thus providing an opportunity for translational work between model systems and human immunology. Opportunities in human biology and disease are available in autoimmune and immune-mediated inflammatory diseases, malignant diseases, host-defense defense including vaccine development, and transplantation immunology. Outstanding investigator-based and core-based facilities are available. Resources include state-of-the-art high-speed flow cytometry, high resolution imaging (confocal, FRET, standard and cryo-election microscopy), nucleic acid and protein sequencing, hybridoma/phage display antibody production, and transgenic/ES cell mouse facilities.

Postdoctoral trainees with an M.D., Ph.D. or equivalent terminal degree are selected on the basis of prior academic and research performance, letters of recommendation, and personal interviews. Successful candidates will demonstrate a strong commitment to a research and teaching career in investigative biomedical sciences. For further information, please contact Dr. Robert Kimberly, E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. .

UAB News

  • As kids prepare to head back to school, required immunizations are typically on the to-do list, but getting potentially lifesaving vaccines should not end when adulthood begins, says one University of Alabama at Birmingham infectious diseases expert.

  • effrey R. Curtis, M.D., from the University of Alabama at Birmingham, and colleagues utilized 1998 to 2011 data from the U.S. Veterans Health Administration to identify RA patients initiating rituximab, abatacept, or anti-tumor necrosis factor (anti-TNF) therapy. The authors sought to assess the comparative risk of hospitalized infection associated with anti-TNF and non-anti-TNF biologic agents.

UAB Research News

  • New drugs to slow or even prevent Parkinson’s could be in human studies as early as 2015.Written by Matt Windsor An enzyme closely associated with genetic forms of Parkinson’s disease appears to play a larger role in its progression than previously thought, say investigators at the University of Alabama at Birmingham. The new research offers encouraging evidence that drugs to block this enzyme, known as leucine-rich repeat kinase 2 or LRRK2, could slow — or even...

  • UAB School of Nursing's federally funded study shows both the patient and caregiver benefit from early palliative care.The earlier a specific phone-based, palliative care support program can be introduced to caregivers, the better they will be able to cope with the caregiving experience, according to research conducted by University of Alabama at Birmingham School of Nursing investigators. The patient outcomes from the study, known as ENABLE III, were presented June 3 at the American Society of...