G6600 - Pathology

Contact:

Mentor:  Upender Manne, Ph.D., Professor of Pathology- Mailing address:  1530 3rd Avenue South, Physical address: 1802, 6th Avenue south - Wallace Tumor Institute - Room # 420A, Comprehensive Cancer Center, Birmingham, AL 35294; Telephone:  (205) 934-4276; E-mail: manne@uab.edu


Dr. Manne’s laboratory focuses on translational research for human neoplasias, with emphasis on colorectal and breast cancers. His laboratory, with projects funded by the National Cancer Institute, is evaluating molecular markers and their underlying mechanisms, to identify aggressive phenotypic features of tumors to predict the efficacy of chemotherapeutic regimens and to assess clinical outcomes. The studies will be performed in collaboration with experts from the fields of molecular biology, clinical oncology, pathology, cell biology, epidemiology, statistics, and bioinformatics. The findings of these approaches, involving biomarker discovery, validation and bioinformatics/statistical modeling, will aid in developing predictive models specific for individual patients. Experience in cancer genetics, cancer cell biology, cancer tissue profiling, and molecular cancer biology is desirable. 

To apply:  Send a letter of intent describing research accomplishments and plans, CV, and the names and contact information of three references to Dr. Manne at manne@uab.edu.

UAB News

  • According to Bruce Korf, M.D., Ph.D., chair of the department of genetics, and director of the Heflin Center for Genomic Sciences at the University of Alabama at Birmingham, the glut of genetic information that will be used to inform treatment decisions will require additional education of clinicians, especially since a sizable cohort received their genetics training before the genomic age.

  • "If someone has hepatitis C and does not know it, it could be doing damage to their liver," says Michael Saag, MD, professor of medicine and director of the Center for AIDS Research at the University of Alabama at Birmingham. He is also co-chair of the Infectious Diseases Society of America's HCV Guidance panel.