G6600 - Pathology
Dr. Manne’s laboratory focuses on translational research for human neoplasias, with emphasis on colorectal and breast cancers. His laboratory, with projects funded by the National Cancer Institute, is evaluating molecular markers and their underlying mechanisms, to identify aggressive phenotypic features of tumors to predict the efficacy of chemotherapeutic regimens and to assess clinical outcomes. The studies will be performed in collaboration with experts from the fields of molecular biology, clinical oncology, pathology, cell biology, epidemiology, statistics, and bioinformatics. The findings of these approaches, involving biomarker discovery, validation and bioinformatics/statistical modeling, will aid in developing predictive models specific for individual patients. Experience in cancer genetics, cancer cell biology, cancer tissue profiling, and molecular cancer biology is desirable.