B14006 - Department of Chemistry

Mentor:  Margaret Johnson, PhD, Assistant Professor, Department of Chemistry, University of Alabama at Birmingham, CHEM 274, 1720 2nd Avenue South, Birmingham, AL 35294-1240, (205) 934-8137, (205) 934-2543 fax

Postdoctoral Fellowship in Protein Structure and Function

A post-doctoral fellowship is available at the University of Alabama at Birmingham in the laboratory of Dr. Margaret Johnson. We use solution NMR spectroscopy and other biophysical techniques to investigate the structure and function of proteins involved in the metabolism and molecular recognition of poly(ADP-ribose), a key biomolecule in the maintenance of genome integrity, chromatin structure, and the cell cycle. Areas of research include determining high-resolution structures of proteins and protein complexes, enzymatic synthesis and computational simulations.

Our laboratory is part of the Comprehensive Cancer Center and Center for Structural Biology at UAB. The Central Alabama High-Field NMR Facility is equipped with Bruker 850, 700, 600 and 500 MHz spectrometers with TCI cryoprobes. Biophysics facilities include MALDI-TOF mass spectrometry, fluorescence spectroscopy, analytical ultracentrifugation, titration calorimetry, high-throughput screening and protein crystallization, and high-performance computing.

UAB is the top university and 8th overall institution in the Best Places to Work (Postdocs) survey published in The Scientist (2013). The campus is a major part of the downtown landscape, and is within walking distance of some of the best parks, entertainment and dining in the region. We offer high-quality training and mentoring, pay and benefits, career development, networking, and opportunities for family and personal life. The Office of Postdoctoral Education offers classes in grant writing, laboratory management, research ethics, and teaching and presentation skills. Interdisciplinary research seminars are ongoing in a variety of university-wide interest groups.

Enthusiastic, motivated researchers are encouraged to apply. Candidates should have recently received a Ph.D. in a related discipline and have a strong background in structural biology or biochemistry. To apply please send a cover letter, CV, and contact information for three references to Dr. Margaret Johnson at This email address is being protected from spambots. You need JavaScript enabled to view it. . UAB is an equal opportunity/affirmative action employer.

 

 

 

 

 

 

 

 

UAB News

  • Becker’s Hospital Review has named the UAB Comprehensive Cancer Center as one of the “100 Hospitals and Health Systems With Great Oncology Programs.” Becker’s Hospital Review has named the UAB Comprehensive Cancer Center as one of the nation’s “100 Hospitals and Health Systems With Great Oncology Programs.” The UAB Cancer Center, the only one from the state of Alabama, was selected for the 2014 edition of its list for leading the way in quality patient care,...

  • A 2010 study by researchers at the University of Alabama at Birmingham found that among a group of more than 100 premenopausal women, fat was significantly reduced in those who consumed the most calcium-rich foods.

UAB Research News

  • New drugs to slow or even prevent Parkinson’s could be in human studies as early as 2015.Written by Matt Windsor An enzyme closely associated with genetic forms of Parkinson’s disease appears to play a larger role in its progression than previously thought, say investigators at the University of Alabama at Birmingham. The new research offers encouraging evidence that drugs to block this enzyme, known as leucine-rich repeat kinase 2 or LRRK2, could slow — or even...

  • UAB School of Nursing's federally funded study shows both the patient and caregiver benefit from early palliative care.The earlier a specific phone-based, palliative care support program can be introduced to caregivers, the better they will be able to cope with the caregiving experience, according to research conducted by University of Alabama at Birmingham School of Nursing investigators. The patient outcomes from the study, known as ENABLE III, were presented June 3 at the American Society of...