B14006 - Department of Chemistry

Mentor:  Margaret Johnson, PhD, Assistant Professor, Department of Chemistry, University of Alabama at Birmingham, CHEM 274, 1720 2nd Avenue South, Birmingham, AL 35294-1240, (205) 934-8137, (205) 934-2543 fax

Postdoctoral Fellowship in Protein Structure and Function

A post-doctoral fellowship is available at the University of Alabama at Birmingham in the laboratory of Dr. Margaret Johnson. We use solution NMR spectroscopy and other biophysical techniques to investigate the structure and function of proteins involved in the metabolism and molecular recognition of poly(ADP-ribose), a key biomolecule in the maintenance of genome integrity, chromatin structure, and the cell cycle. Areas of research include determining high-resolution structures of proteins and protein complexes, enzymatic synthesis and computational simulations.

Our laboratory is part of the Comprehensive Cancer Center and Center for Structural Biology at UAB. The Central Alabama High-Field NMR Facility is equipped with Bruker 850, 700, 600 and 500 MHz spectrometers with TCI cryoprobes. Biophysics facilities include MALDI-TOF mass spectrometry, fluorescence spectroscopy, analytical ultracentrifugation, titration calorimetry, high-throughput screening and protein crystallization, and high-performance computing.

UAB is the top university and 8th overall institution in the Best Places to Work (Postdocs) survey published in The Scientist (2013). The campus is a major part of the downtown landscape, and is within walking distance of some of the best parks, entertainment and dining in the region. We offer high-quality training and mentoring, pay and benefits, career development, networking, and opportunities for family and personal life. The Office of Postdoctoral Education offers classes in grant writing, laboratory management, research ethics, and teaching and presentation skills. Interdisciplinary research seminars are ongoing in a variety of university-wide interest groups.

Enthusiastic, motivated researchers are encouraged to apply. Candidates should have recently received a Ph.D. in a related discipline and have a strong background in structural biology or biochemistry. To apply please send a cover letter, CV, and contact information for three references to Dr. Margaret Johnson at maggiejohnson@uab.edu. UAB is an equal opportunity/affirmative action employer.

 

 

 

 

 

 

 

 

UAB News

  • The Sept. 25-26 Birmingham event is designed for college and university instructors and professors, practice educators, and health care training and development staff who desire to learn strategies for working with, engaging and supporting diverse student and employee populations.The University of Alabama at Birmingham School of Nursing, in conjunction with the Fourth Cultural Competency Faculty Institute, will host the “Cultural Competency in Our Diverse Society: Increasing the Nursing Workforce Diversity Pipeline” on Thursday and Friday,...

  • Discussion will cover the possibility that medical advances would allow humans to live much longer lives.Steven Austad, Ph.D., chair of the University of Alabama at Birmingham’s Department of Biology, will kick off this year’s Theodore Haddin Arts and Sciences Forum on Friday, Sept. 26. Austad’s discussion will cover the unprecedented historical increase in health and longevity over the past century and discuss how recent advances in the basic biology of aging make a healthy 150-year lifespan...