B14006 - Department of Chemistry

Mentor:  Margaret Johnson, PhD, Assistant Professor, Department of Chemistry, University of Alabama at Birmingham, CHEM 274, 1720 2nd Avenue South, Birmingham, AL 35294-1240, (205) 934-8137, (205) 934-2543 fax

Postdoctoral Fellowship in Protein Structure and Function

A post-doctoral fellowship is available at the University of Alabama at Birmingham in the laboratory of Dr. Margaret Johnson. We use solution NMR spectroscopy and other biophysical techniques to investigate the structure and function of proteins involved in the metabolism and molecular recognition of poly(ADP-ribose), a key biomolecule in the maintenance of genome integrity, chromatin structure, and the cell cycle. Areas of research include determining high-resolution structures of proteins and protein complexes, enzymatic synthesis and computational simulations.

Our laboratory is part of the Comprehensive Cancer Center and Center for Structural Biology at UAB. The Central Alabama High-Field NMR Facility is equipped with Bruker 850, 700, 600 and 500 MHz spectrometers with TCI cryoprobes. Biophysics facilities include MALDI-TOF mass spectrometry, fluorescence spectroscopy, analytical ultracentrifugation, titration calorimetry, high-throughput screening and protein crystallization, and high-performance computing.

UAB is the top university and 8th overall institution in the Best Places to Work (Postdocs) survey published in The Scientist (2013). The campus is a major part of the downtown landscape, and is within walking distance of some of the best parks, entertainment and dining in the region. We offer high-quality training and mentoring, pay and benefits, career development, networking, and opportunities for family and personal life. The Office of Postdoctoral Education offers classes in grant writing, laboratory management, research ethics, and teaching and presentation skills. Interdisciplinary research seminars are ongoing in a variety of university-wide interest groups.

Enthusiastic, motivated researchers are encouraged to apply. Candidates should have recently received a Ph.D. in a related discipline and have a strong background in structural biology or biochemistry. To apply please send a cover letter, CV, and contact information for three references to Dr. Margaret Johnson at This email address is being protected from spambots. You need JavaScript enabled to view it. . UAB is an equal opportunity/affirmative action employer.

 

 

 

 

 

 

 

 

UAB News

  • "We have a broader array of workers than you'd see in other cities, from hourly employees in mining and manufacturing to CEOs of biotech firms," says Jack Howard, Ph.D., associate dean at the University of Alabama at Birmingham's Collat School of Business. "It's a laid-back culture, but there's a very strong work ethic."

  • There are a lot of regimens being tried in transplant, and most include calcineurin inhibitors that have significant toxicity," Anupam Agarwal, MD, of the University of Alabama at Birmingham, told MedPage Today. "Hence, if one could safely reduce the dose of the calcineurin inhibitor and still benefit from its immunosuppressive properties, it would be huge advance."

UAB Research News

  • Shirey, who will be inducted in September, is nationally recognized for her innovative integration of teaching and learning strategies.Maria R. Shirey, Ph.D., professor and assistant dean for Clinical Affairs and Partnerships in the University of Alabama at Birmingham School of Nursing, has been selected for induction as a fellow into the National League for Nursing Academy of Nursing Education. Shirey is nationally recognized for her innovative integration of teaching and learning strategies using research, evidence-based practice...

  • The Quad Rider makes it easy to shift gears and brake, enabling people with poor grip-control to safely cycle.The University of Alabama at Birmingham and the Lakeshore Foundation are partnering with InvoTek, Inc., to create a gear and braking device that helps people with disabilities who have limited or no use of their hands operate a handcycle safely. InvoTek, a research and development company in Alma, Arkansas, has received a $175,000 Phase I Small Business Innovation...