B14006 - Department of Chemistry

Mentor:  Dr. Margaret Johnson, Assistant Professor, Department of Chemistry, University of Alabama at Birmingham, CHEM 274, 1720 2nd Avenue South, Birmingham, AL 35294-1240. Telephone:  (205) 934-8137 Fax: (205) 934-2543

A Postdoctoral fellowship is available at the University of Alabama at Birmingham in the laboratory of Dr. Margaret Johnson. We use solution NMR spectroscopy and other biophysical techniques to investigate the structure and function of proteins involved in the metabolism and molecular recognition of poly(ADP-ribose), a key biomolecule in the maintenance of genome integrity, chromatin structure, and the cell cycle. Areas of research include determining high-resolution structures of proteins and protein complexes, enzymatic synthesis and computational simulations.

Our laboratory is part of the Comprehensive Cancer Center and Center for Structural Biology at UAB. The Central Alabama High-Field NMR Facility is equipped with Bruker 850, 700, 600 and 500 MHz spectrometers with TCI cryoprobes. Biophysics facilities include MALDI-TOF mass spectrometry, fluorescence spectroscopy, analytical ultracentrifugation, titration calorimetry, high-throughput screening and protein crystallization, and high-performance computing.

UAB is the top university and 8th overall institution in the Best Places to Work (Postdocs) survey published in The Scientist (2013). The campus is a major part of the downtown landscape, and is within walking distance of some of the best parks, entertainment and dining in the region. We offer high-quality training and mentoring, pay and benefits, career development, networking, and opportunities for family and personal life. The Office of Postdoctoral Education offers classes in grant writing, laboratory management, research ethics, and teaching and presentation skills. Interdisciplinary research seminars are ongoing in a variety of university-wide interest groups.

Enthusiastic, motivated researchers are encouraged to apply. Candidates should have recently received a Ph.D. in a related discipline and have a strong background in structural biology or biochemistry. To apply please send a cover letter, CV, and contact information for three references to Dr. Margaret Johnson at maggiejohnson@uab.edu. UAB is an equal opportunity/affirmative action employer.

  

Postdocs in UAB News

  • UAB School of Public Health research published in the journal Obesity shows seeing, hearing and smelling others’ eating foods can cause low birthweight in offspring among mice.While studies have shown that what a mother eats during pregnancy can affect her offspring, it could be that what she sees others eating can also affect her offspring. New research from the University of Alabama at Birmingham School of Public Health explores the influence it has in a...

  • Early palliative care offers statistically beneficial effects on patient survival and family caregiver burden, according to articles published in the Journal of Clinical Oncology.Two papers recently published by University of Alabama at Birmingham School of Nursing researchers in the Journal of Clinical Oncology highlight the need for a “culture shift” by clinicians and the general public to engage palliative care services long before a person reaches the final stage of life. Two articles reporting on 207...

UAB Research News

  • UAB discovery gives better understanding of and potential therapies for septic shock and reperfusion injuries.Amit GaggarA single layer of endothelial cells and extracellular matrix lines the inside of blood vessels, like the inner tube inside a bicycle tire. Injury and inflammation can damage this thin layer, allowing a dangerous leakage of fluid from blood vessels to tissues. When this happens in the lung it can lead to acute respiratory distress syndrome, or ARDS, a major...

  • Here’s a look at the many fellowships, scholarships, honors and awards earned by the talented 2015 spring graduates at UAB.Earning a college degree is one of the defining moments of accomplishment in life. For some among the University of Alabama at Birmingham’s graduating class this spring, that success was sweetened with the added honors of awards, fellowships and scholarships. Ameen Barghi, who graduates with degrees in neuroscience and an individually designed major in translational research in...