D221402 - Microbiology

Mentor:  Dr. Hubert M. Tse, 
Assistant Professor, Department of Microbiology, Comprehensive Diabetes Center, University of Alabama at Birmingham, SHEL 1202, 1825 University Boulevard, Birmingham, AL 35294. Email:  htse@uab.edu

A Postdoctoral position is available in the laboratory of Hubert Tse in the Department of Microbiology, Comprehensive Diabetes Center, at the University of Alabama at Birmingham. Our research examines the role of oxidative stress on autoimmune responses in Type 1 diabetes (T1D). Through the use of novel immunotherapeutics and murine models of T1D, we can determine how reactive oxygen species (ROS) synthesis contributes to innate immune responses and autoreactive T cell effector mechanisms involved in pancreatic beta-cell destruction (Padgett et al. NY Annals, 2013).

We seek a motivated, creative, and energetic applicant to define the role of ROS synthesis on anti-viral responses to diabetogenic viral triggers (Coxsackievirus) of T1D in both murine models and human translational studies. The laboratory uses immunological methods, molecular biology, cellular biochemistry, redox biology, murine models of T1D, microscopic imaging, and flow cytometry to discover and evaluate new mechanisms of autoimmune dysregulation.

Candidates must have a recent Ph.D. and/or M.D., or equivalent. Priority will be given to qualified candidates with a strong background in immunology, molecular biology, biochemistry, flow cytometry, and diabetes-related research. Experience with mice is also preferred, but not required. Salary will follow NIH guidelines commensurate with training and experience. Competitive applicants will have a proven track record in terms of publications and independent funding.

If interested, please send a letter describing your research experience/interest/future career aspirations, your CV, and contact information for three references electronically to: htse@uab.edu

Postdocs in UAB News

  • Stephen Carter will attend the Experimental Biology Conference in late March to receive his award.Stephen J. Carter, Ph.D., postdoctoral fellow in the University of Alabama at Birmingham Department of Human Studies and the Nutrition Obesity Research Center, has been awarded the American Physiological Society’s Environmental and Exercise Physiology (EEP) section Partnership for Clean Competition New Investigator Award. The award recognizes outstanding experimental research in environmental, exercise or thermal physiology by a postdoctoral fellow involving ergogenics and detection...

  • Poster sessions and guest lecturers celebrate Darwin’s legacy.To honor the 206th birthday of legendary evolutionary biologist Charles Darwin, the University of Alabama at Birmingham will host Darwin Day on Thursday, Feb. 12, and Friday, Feb. 13. The events will celebrate scientific research in evolutionary biology and other disciplines. “Charles Darwin’s great discovery, the principle of natural selection, is more relevant to science than ever before,” said Steven Austad, Ph.D., chair of the Department of Biology. “For...

UAB Research News

  • Guest speaker and former Surgeon General Regina Benjamin among many who will see new approaches and successful models of current health-disparities research.Mona FouadThe UAB Minority Health & Health Disparities Research Center (MHRC) will host the 2015 UAB Health Disparities Research Symposium, “The Science of Health Disparities: From Social Causes to Personalized Medicine,” March 17-18 in the DoubleTree by Hilton on 20th Street South in Birmingham. In its 10th year, the symposium highlights work by undergraduate,...

  • Previous research indicated six weeks of treatment improved hearing, but new findings published in the New England Journal of Medicine reveal six months is better.Babies treated for symptomatic cytomegalovirus (CMV) infection for six months, instead of the standard six weeks, have better hearing and developmental outcomes, according to a new study from the University of Alabama at Birmingham. One in 150 babies will be born with CMV, and about one of every five of those children...