D140280 - Department of Pathology

Mentor:  Dr. Joanne E. Murphy-Ullrich, Professor of Pathology, Co-Director, BioMatrix Engineering and Regenerative Medicine Center, VH G001, 1720 2nd Avenue South, Birmingham, AL 35294-0019, Email: murphy@uab.edu

A Postdoctoral position is available in the laboratory of Joanne Murphy-Ullrich, Ph.D., in the Department of Pathology at the Alabama at Birmingham. Our research examines the role of the endoplasmic reticulum stress protein calreticulin in regulating TGF-beta signaling and fibrosis through control of calcium-dependent signaling. This position is funded by a new grant to study the role of calreticulin in TGF-beta signaling in the kidney proximal tubule under diabetic conditions. The applicant will be expected to examine in vitro mechanisms of calreticulin-TGF-beta regulation under high glucose and oxidant conditions and also to perform in vivo studies using several novel mouse models of diabetic nephropathy.

Candidates must have a recent Ph.D. and/or M.D., or equivalent. Priority will be given to qualified candidates with a strong background in cell culture, molecular biology, biochemistry, animal models, and diabetes-related research. The candidate will be expected to write manuscripts and present his/her work at scientific meetings and assist with training of graduate level personnel in the lab. Salary (with benefits) will follow NIH guidelines commensurate with training and experience. Competitive applicants should have a proven track record with publications and the potential for career development. UAB is a highly collegial and interactive environment that has an active Office of Post-doctoral Education which provides mentoring and career guidance in addition to that provided by the mentor.

If interested, please send a letter describing your research experience/interest/future career goals, your CV, and contact information for three references electronically to murphy@uab.edu.

Postdocs in UAB News

  • Increased risk of major adverse cardiac events after the later surgery persists for one year.Carla HolcombA patient who has noncardiac surgery sometime after a stent is put into a coronary artery to open up a blockage has a greater risk for major adverse cardiac events (MACE) following the operation, but the optimal time to delay such elective surgery after stenting was not known. In a study of more than 28,000 patient records, first author Carla Holcomb,...

  • UAB School of Public Health research published in the journal Obesity shows seeing, hearing and smelling others’ eating foods can cause low birthweight in offspring among mice.While studies have shown that what a mother eats during pregnancy can affect her offspring, it could be that what she sees others eating can also affect her offspring. New research from the University of Alabama at Birmingham School of Public Health explores the influence it has in a...

UAB Research News

  • Two children die each day in the United States as a result of poisoning. UAB child safety expert David Schwebel, Ph.D., works to prevent this from occurring.Click to enlargeThe summer months often mean more time spent at home for kids. While the break from the books can be enjoyable, one University of Alabama at Birmingham child safety expert says there is one important lesson both children and parents still need to learn: how to prevent...

  • Patients awaiting liver transplant who have primary biliary cirrhosis (PBC) had higher wait-list mortality compared with other patients on the liver transplant list, said researchers.