D140280 - Department of Pathology

Mentor:  Dr. Joanne E. Murphy-Ullrich, Professor of Pathology, Co-Director, BioMatrix Engineering and Regenerative Medicine Center, VH G001, 1720 2nd Avenue South, Birmingham, AL 35294-0019, Email: murphy@uab.edu

A Postdoctoral position is available in the laboratory of Joanne Murphy-Ullrich, Ph.D., in the Department of Pathology at the Alabama at Birmingham. Our research examines the role of the endoplasmic reticulum stress protein calreticulin in regulating TGF-beta signaling and fibrosis through control of calcium-dependent signaling. This position is funded by a new grant to study the role of calreticulin in TGF-beta signaling in the kidney proximal tubule under diabetic conditions. The applicant will be expected to examine in vitro mechanisms of calreticulin-TGF-beta regulation under high glucose and oxidant conditions and also to perform in vivo studies using several novel mouse models of diabetic nephropathy.

Candidates must have a recent Ph.D. and/or M.D., or equivalent. Priority will be given to qualified candidates with a strong background in cell culture, molecular biology, biochemistry, animal models, and diabetes-related research. The candidate will be expected to write manuscripts and present his/her work at scientific meetings and assist with training of graduate level personnel in the lab. Salary (with benefits) will follow NIH guidelines commensurate with training and experience. Competitive applicants should have a proven track record with publications and the potential for career development. UAB is a highly collegial and interactive environment that has an active Office of Post-doctoral Education which provides mentoring and career guidance in addition to that provided by the mentor.

If interested, please send a letter describing your research experience/interest/future career goals, your CV, and contact information for three references electronically to murphy@uab.edu.

Postdocs in UAB News

  • UAB School of Public Health research published in the journal Obesity shows seeing, hearing and smelling others’ eating foods can cause low birthweight in offspring among mice.While studies have shown that what a mother eats during pregnancy can affect her offspring, it could be that what she sees others eating can also affect her offspring. New research from the University of Alabama at Birmingham School of Public Health explores the influence it has in a...

  • Early palliative care offers statistically beneficial effects on patient survival and family caregiver burden, according to articles published in the Journal of Clinical Oncology.Two papers recently published by University of Alabama at Birmingham School of Nursing researchers in the Journal of Clinical Oncology highlight the need for a “culture shift” by clinicians and the general public to engage palliative care services long before a person reaches the final stage of life. Two articles reporting on 207...

UAB Research News

  • The protective effect is achieved by reducing acute inflammation in the spleen and the left ventricle of the heart.Ganesh HaladeChronic inflammation provokes a downward spiral in many diseases, including congestive heart failure, atherosclerosis and peripheral artery disease. A University of Alabama at Birmingham-led research team has now found that mice that are given the lipid “Resolvin D1” after experimental heart attacks have substantially reduced amounts of inflammation and heart failure. “Thus, Resolvin D1 has the potential...

  • UAB gets $11 million grant for potential groundbreaking study of beta blockers for patients with COPD.Researchers at the University of Alabama at Birmingham will lead a multisite study of the role of beta blockers in patients with chronic obstructive pulmonary disease, or COPD. The study is funded by an $11 million grant from the United States Department of Defense. COPD is the third leading cause of death in the United States and is among the most...