I13272—Microbiology

Contact:

Mentor:  Michael Niederweis, PhD, Professor, Microbiology and Biochemistry, 845 19th Street South, BBRB 609, Birmingham, AL 35294-2710,205-996-2711 phone, 205-996-4008 fax, mnieder@uab.edu


Two POSTDOCTORAL POSITIONS are available in the UAB Microbiology Department:

1. A revolutionary method of sequencing DNA utilizes nanopores. The porin MspA was discuvered by us and has become the nanopore for DNA sequencing (PNAS 107, 16060: 2010; Nat. Biotechnol. 30, 349; 2012). The goal of this project is to improve the properties of the MspA pore for DNA sequencing by protein engineering. Experience with protein design, modeling, biochemistry and purification is required and must be documented in publications. A background in electrophysiology is beneficial.

2. Iron is an essential nutrient for most bacteria including Mycobacterium tuberculosis. We have discovered a new siderophore secretion system and identified iron utilization as a key virulence trait of Mtb (PLoS Pathogens 9, e1003120; 2013). The goal of this project is to characterize membrane transporter required for uptake of siderophores and heme. Experience in molecular microbiology, preferable with pathogenic bacteria, is required and must be documented in publications.

Please send your cv to Michael Niederweis (mnieder@uab.edu).

Postdocs in UAB News

  • Increased risk of major adverse cardiac events after the later surgery persists for one year.Carla HolcombA patient who has noncardiac surgery sometime after a stent is put into a coronary artery to open up a blockage has a greater risk for major adverse cardiac events (MACE) following the operation, but the optimal time to delay such elective surgery after stenting was not known. In a study of more than 28,000 patient records, first author Carla Holcomb,...

  • UAB School of Public Health research published in the journal Obesity shows seeing, hearing and smelling others’ eating foods can cause low birthweight in offspring among mice.While studies have shown that what a mother eats during pregnancy can affect her offspring, it could be that what she sees others eating can also affect her offspring. New research from the University of Alabama at Birmingham School of Public Health explores the influence it has in a...

UAB Research News

  • Patients awaiting liver transplant who have primary biliary cirrhosis (PBC) had higher wait-list mortality compared with other patients on the liver transplant list, said researchers.

  • Stylish but dangerous? UAB study looks at injuries caused by wearing high-heeled shoes.Americans love high-heeled shoes. One survey in 2003 reported that 62 percent of American women wore shoes with a 2-inch or greater heel on a regular basis. Those shoes are taking a toll. New research from the University of Alabama at Birmingham shows that high-heeled-shoe-related injuries doubled between 2002 and 2012. The findings were published online May 12 in the Journal of Foot and...