Publications

  • 2014
  • 2013
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  • 2010
  • 2009
  • 2008
  • 2007
  • 2006
  • 2005
  • 2004
  • 2003
  • Pre 2003
  1. Glinskii OV, Li F, Wilson LS, Barnes S, Rittenhouse-Olson K, Barchi JJ Jr, Pienta KJ, Glinsky VV.
    Endothelial integrin α3β1 stabilizes carbohydrate-mediated tumor/endothelial cell adhesion and induces macromolecular signaling complex formation at the endothelial cell membrane.
    Oncotarget. 2014 Mar 15;5(5):1382-9. [PMID: 24675526] [PMCID: PMC4012737]

  2. Legette LL, Prasain J, King J, Arabshani A, Barnes S, Weaver CM.
    Pharmacokinetics of Equol, a Soy Isoflavone Metabolite, Changes with Form of Equol (Dietary vs. Intestinal Production) in Ovariectomized Rats.
    J Agric Food Chem. 2014 Jan 21 [PMID: 24446705]

  1. Whitehouse-Tedd K, Cave N, Ugarte C, Tucker L, Prasain JK, Arabshahi A, Barnes S, Hendriks W, Thomas D.
    Isoflavone metabolism in domestic cats (Felis catus): comparison of plasma metabolites detected after ingestion of two different dietary forms of genistein and daidzein.
    J Anim Sci. 2013 Mar;91(3):1295-306. [PMID: 23307849] [doi: 10.2527/jas.2011-4812]

  2. Viera L, Radmilovich M, Vargas MR, Dennys CN, Wilson L, Barnes S, Franco MC, Beckman JS, Estévez AG.
    Temporal patterns of tyrosine nitration in embryo heart development.
    Free Radic Biol Med. 2013 Feb;55:101-8. [PMID: 23195686]

  3. Franco MC, Ye Y, Refakis C, Feldman JL, Stokes AL, Basso M, Melero Fernández de Mera RM, Calingasan NY, Kiaei M, Barnes S, Beal MF, Beckman JS, Mehl R, Estévez AG.
    Nitration of Hsp90 induces cell death.
    PNAS, 110:E1102-11. [PMCID: PMC3607042]

  4. Bolisetty S, Traylor AM, Zarjou A, Johnson MS, Benavides GA, Ricart K, Boddu R, Moore RD, Landar A, Barnes S, Darley-Usmar VM, Agarwal A.
    Mitochondria-targeted heme oxygenase-1 decreases oxidative stress in renal epithelial cells.
    Am J Physiol Renal Physiol. 2013 305:F255-F264 [PMID: 23720344]

  5. Mitchell T, Johnson MS, Ouyang O, Chacko BK, Mitra K, Lei X, Gai Y, Moore DR, Barnes S, Zhang J, Koizumi A, Ramanadham S, Darley-Usmar. VM.
    Dysfunctional mitochondrial bioenergetics and oxidative stress in Akita+/Ins2-derived β-cells.
    Am J Physiol Endocrinol Metab. 2013 Jul 2. [Epub ahead of print] [PMID: 23820623]

  6. Ulasova E, Perez J, Hill BG, Dubuisson JG, Bradley WE, Garber DW, Landar A, Barnes S, Prasain J, Parks DA, Dell’Italia LJ, Darley-Usmar VM.
    Quercetin prevents left ventricular hypertrophy in the Apo E knockout mouse.
    Redox Biol. 2013 Jul 16;1(1):381-6. [PMID: 24024175]

  7. Wetta LA, Biggio JR, Cliver S, Abramovici A, Barnes S, Tita AT.
    Is Midtrimester Vitamin D Status Associated with Spontaneous Preterm Birth and Preeclampsia?
    Am J Perinatol. 2013 Sep 10. [Epub ahead of print] [PMID: 24022379]

  8. Chiquito Crasto, Chandrahas Narne, Mikako Kawai, Landon Wilson and Stephen Barnes
    MRMPath and MRMutation, Facilitating Discovery of Mass Transitions for Proteotypic Peptides in Biological Pathways Using a Bioinformatics Approach
    Advances in Bioinformatics, vol. 2013, Article ID 527295, 10 pages, 2013. [doi: 10.1155/2013/527295]

  9. Jeevan K. Prasain, Alireza Arabshahi, Pam R. Taub, Scott Sweeney, Ray Moore, J. Daniel Sharer, Stephen Barnes.
    Simultaneous quantification of F2-isoprostanes and prostaglandins in human urine by liquid chromatography tandem-mass spectrometry
    Journal of Chromatography B. Volumes 913–914, 15 January 2013, Pages 161–168 [doi: 10.1016/j.jchromb.2012.12.009]
  1. Cheng GC, Chen DT, Chen JJ, Soong SJ, Lamartiniere C, Barnes S.
    A chain reaction approach to modelling gene pathways.
    Transl Cancer Res. 2012 Aug 1;1(2):61-73. Epub 2012 May 31. [PMID: 22943042]

  2. Higdon A, Landar A, Barnes S, Darley-Usmar VM.
    The Electrophile Responsive Proteome: Integrating Proteomics and Lipidomics with Cellular Function.
    Antioxidants & Redox Signaling, 2012 Dec 1;17(11):1580-9. Epub 2012 Apr 18. [PMID: 22352679]

  3. Wong WW, Taylor AA, E. Smith EO, Barnes S, Hachey DL.
    Effect of soy isoflavone supplementation on nitric oxide metabolism and blood pressure in menopausal women.
    American Journal of Clinical Nutrition. American Journal of Clinical Nutrition, 2012 Jun;95(6):1487-94. [PMID: 22552034]

  4. Li H, Cao, Z, Moore DR, Patricia L. Jackson PL, Barnes S, Lambeth JD, Thannickal VJ, Cheng G.
    Microbicidal Activity of VPO1 in Human Plasma via Generation of HOCl. Li H, Cao, Z, Moore DR, Patricia L. Jackson PL, Barnes S, Lambeth JD, Thannickal VJ, Cheng G. Microbicidal Activity of VPO1 in Human Plasma via Generation of HOCl.
    Infection and Immunity. 2012 Jul;80(7):2528-37. Epub 2012 Apr 23 [PMID: 22526679]

  5. McClure M, DeLucas LJ, Wilson L, Ray M, Rowe SM, Wu X, Dai Q, Hong JS, Sorscher EJ, Kappes JC, Barnes S.
    Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications. Protein Eng Des Sel. 2012 Jan;25(1):7-14. Epub 2011 Nov 25. [PMID: 22119790] [PMCID: PMC3276306]
  1. Whitehouse-Tedd KM, Cave NJ, Ugarte CE, Waldron LA, Prasain JK, Arabshahi A, Barnes S, Thomas DG.
    Dietary isoflavone absorption, excretion, and metabolism in captive cheetahs (Acinonyx jubatus).
    J Zoo Wildl Med. 2011 Dec;42(4):658-70. [PMID: 22204061] [doi:10.1638/2011-0060.1]

  2. Li FJ, Kubagawa Y, McCollum MK, Wilson L, Motohashi T, Bertoli LF, Barton JC, Barnes S, Davis RS, Kubagawa H.
    Enhanced levels of both membrane-bound and soluble forms of IgM Fc receptor in patients with chronic lymphocytic leukemia.
    Blood. 2011 Sep 9. [Epub ahead of print] [PMID: 21908424]

  3. Barnes S, Prasain J, D'Alessandro T, Arabshahi A, Botting N, Lila MA, Jackson G, Janle EM, Weaver CM.
    The metabolism and analysis of isoflavones and other dietary polyphenols in foods and biological systems.
    Food Funct. 2011 May 25;2(5):235-44. [PMID: 21779561]

  4. Li F, Glinskii OV, Zhou J, Wilson LS, Barnes S, Anthony DC, Glinsky VV.
    Identification and analysis of signaling networks potentially involved in breast carcinoma metastasis to the brain.
    PLoS One. 2011;6(7):e21977. [PMID: 21779361]

  5. Legette LL, Lee WH, Martin BR, Story JA, Arabshahi A, Barnes S, Weaver CM.
    Genistein, a phytoestrogen, improves total cholesterol, and Synergy, a prebiotic, improves calcium utilization, but there were no synergistic effects.
    Menopause. 2011 Jun 7. [Epub ahead of print] [PMID: 21659907]

  6. Frölich MA, Arabshahi A, Katholi C, Prasain J, Barnes S.
    Hemodynamic characteristics of midazolam, propofol, and dexmedetomidine in healthy volunteers.
    J Clin Anesth. 2011 May;23(3):218-23. [PMID: 21570617]

  7. Mirza S, Wilson L, Benjamin WH Jr, Novak J, Barnes S, Hollingshead SK, Briles DE.
    Serine protease PrtA from Streptococcus pneumoniae plays a role in the killing of S. pneumoniae by apolactoferrin.
    Infect Immun. 2011 Mar 21. [Epub ahead of print] [PMID:21422179]

  8. Anderson JT, Zeng M, Li Q, Stapley R, Moore DR 2nd, Chenna B, Fineberg N, Zmijewski J, Eltoum IE, Siegal GP, Gaggar A, Barnes S, Velu SE, Thannickal VJ, Abraham E, Patel RP, Lancaster JR Jr, Chaplin DD, Dransfield MT, Deshane JS.
    Elevated levels of NO are localized to distal airways in asthma.
    Free Radic Biol Med. 2011 Mar 16. [Epub ahead of print] [PMID:21419218]

  9. Rajbhandari, R, Peng, N, Moore, DR, Arabshahi, A, Wyss, JM, Barnes S, Jeevan K. Prasain JK.
    Determination of cranberry phenolic metabolites in rats by liquid chromatography-tandem mass spectrometry.
    J Agric Food Chem, 2011 [PMID: 21634376]

  10. Floyd KA, Stella DR, Wang CC, Laurentz S, McCabe GP, Srivastava OP, Barnes S.
    Genistein and genistein-containing dietary supplements accelerate the early stages of cataractogenesis in the male ICR/f rat.
    Exp Eye Res. 2011 Feb;92(2):120-7. [PMID: 21147102]

  1. Barnes S, Kim H.
    Cautions and research needs identified at the equol, soy, and menopause research leadership conference.
    J Nutr. 2010 Jul;140(7):1390S-4S. [PMID: 20505015]

  2. Virk-Baker MK, Nagy TR, Barnes S.
    Role of Phytoestrogens in Cancer Therapy.
    Planta Med. 2010 Aug;76(11):1132-42. [PMID: 20597043]

  3. Sun D, Zhuang X, Xiang X, Liu Y, Zhang S, Liu C, Barnes S, Grizzle W, Miller D, Zhang HG.
    A Novel Nanoparticle Drug Delivery System: The Anti-inflammatory Activity of Curcumin Is Enhanced When Encapsulated in Exosomes.
    Mol Ther. 2010 Sep;18(9):1606-14. [PMID: 20571541]

  4. Raska M, Takahashi K, Czernekova L, Zachova K, Hall S, Moldoveanu Z, Elliott MC, Wilson L, Brown R, Jancova D, Barnes S, Vrbkova J, Tomana M, Smith PD, Mestecky J, Renfrow MB, Novak J.
    Glycosylation patterns of HIV-1 gp120 depend on the type of expressing cells and affect antibody recognition.
    J Biol Chem. 2010. 285(27):20860-9. [PMID: 20439465]

  5. Stella DR, Floyd KA, Grey AC, Renfrow MB, Schey KL, Barnes S.
    Tissue localization and solubilities of {alpha}A-crystallin and its numerous C-terminal truncation products in pre- and post-cataractous ICR/f rat lenses.
    Invest Ophthalmol Vis Sci. 2010 Oct;51(10):5153-61. [PMID: 20435586]

  6. Prasain JK, Arabshahi A, Moore DR 2nd, Greendale GA, Wyss JM, Barnes S.
    Simultaneous determination of 11 phytoestrogens in human serum using a 2 min liquid chromatography/tandem mass spectrometry method.
    J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Apr 15;878(13-14):994-1002. Epub 2010 Mar 6. [PMID: 20346741]

  7. Barnes S.
    The biochemistry, chemistry and physiology of the isoflavones in soybeans and their food products.
    Lymphat Res Biol. 2010. 8(1):89-98. [DOI:10.1089/lrb.2009.0030] [PMID: 20235891]

  1. Pyle LC, Fulton JC, Sloane PA, Backer K, Mazur M, Prasain J, Barnes S, Clancy JP, Rowe SM.
    Activation of CFTR by the Flavonoid Quercetin: Potential Use as a Biomarker of ΔF508 CFTR Rescue
    Am J Respir Cell Mol Biol. 2009 Dec 30. [DOI:10.1165/rcmb.2009-0281OC] [PMID: 20042712]

  2. Peng N, Prasain JK, Dai Y, Moore R, Arabshahi A, Barnes S, Carlson S, Wyss JM.
    Chronic dietary kudzu isoflavones improve components of metabolic syndrome in stroke-prone spontaneously hypertensive rats.
    J Agric Food Chem. 26;57(16):7268-73, 2009.. [DOI:10.1021/jf901169y] [PMID: 19938872]

  3. Smith DL Jr, Nagy TR, Wilson LS, Dong S, Barnes S, Allison DB.
    The Effect of Mannan Oligosaccharide Supplementation on Body Weight Gain and Fat Accrual in C57Bl/6J Mice.
    Obesity. 2009 Oct 1. Epub 2009 Oct 1. [DOI: 10.1038/oby.2009.308] [PMID: 19798073]

  4. Wong WW, Lewis RD, Steinberg FM, Murray MJ, Cramer MA, Amato P, Young RL, Barnes S, Ellis KJ, Shypailo RJ, Fraley JK, Konzelmann KL, Fischer JG, Smith EO.
    Soy isoflavone supplementation and bone mineral density in menopausal women: a 2-y multicenter clinical trial.
    Am J Clin Nutr. 2009 Sep 16. Epub 2009 Sep 16. [DOI: 10.3945/ajcn.2009.28001] [PMID: 19759166]

  5. Legette LL, Martin BR, Shahnazari M, Lee WH, Helferich WG, Qian J, Waters DJ, Arabshahi A, Barnes S, Welch J, Bostwick DG, Weaver CM.
    Supplemental dietary racemic equol has modest benefits to bone but has mild uterotropic activity in ovariectomized rats.
    Journal of Nutrition,, 139(10):1908-13. [DOI: 10.3945/jn.109.108225] [PMID: 19710157]

  6. Cox KB, Liu J, Tian L, Barnes S, Yang Q, Wood PA.
    Cardiac hypertrophy in mice with long-chain acyl-CoA dehydrogenase or very long-chain acyl-CoA dehydrogenase deficiency.
    Laboratory Investigation, 2009 Sep 7. [DOI: 10.1038/labinvest.2009.86] [PMID: 19736549]

  7. Weaver CM, Martin BR, Jackson GS, McCabe GP, Nolan JR, McCabe LD, Barnes S, Reinwald S, Boris ME, Peacock M.
    Antiresorptive Effects of Phytoestrogen Supplements Compared to Estradiol or Risedronate in Postmenopausal Women Using 41Ca Methodology.
    J Clin Endocrinol Metab. 2009 Jul 7 [DOI: 10.1210/jc.2009-0332] [PMID: 19584189]

  8. Prasain JK, Peng N, Dai Y, Moore R, Arabshahi A, Wilson L, Barnes S, Michael Wyss J, Kim H, Watts RL.
    Liquid chromatography tandem mass spectrometry identification of proanthocyanidins in rat plasma after oral administration of grape seed extract.
    Phytomedicine, 16(2-3):233-43, 2009. [DOI: 10.1016/j.phymed.2008.08.006] [PMID: 19095430]

  9. Prasain JK, Peng N, Moore R, Arabshahi A, Barnes S, Wyss JM.
    Tissue distribution of puerarin and its conjugated metabolites in rats assessed by liquid chromatography-tandem mass spectrometry.
    Phytomedicine, 16(1); 65-71, 2009. [DOI: 10.1016/j.phymed.2008.09.004] [PMID: 19027277]

  10. Weaver CM, Barnes S, Wyss JM, Kim H, Morré DM, Morré DJ, Simon JE, Lila MA, Janle EM, Ferruzzi MG.
    Research Highlights from the Purdue-UAB Botanicals Research Center for Age Related Diseases.
    Pharm Biol. 2009 47(8):768-773. [PMID: 19890436] [DOI: 10.1080/13880200902988603]
  1. Prasain JK, Arabshahi A, Moore R, Barnes S, Carroll SL.
    A liquid chromatography mass spectrometry assay for determination of PD168393, a specific and irreversible inhibitor of erbB membrane tyrosine kinases, in rat serum.
    Journal of Chromatogr B. 876(2): 219-224, 2008

  2. Barnes, S.
    Nutritional Genomics, Polyphenols, Diets, and Their Impact on Dietetics.
    Journal of the American Dietetic Association, 108(11):1888-95, 2008.

  3. Barnes, S., Shonsey, E.M., Eliuk, S.M., Stella, D., Mafia, K., Kim, H., Srivastava, O.P., Renfrow, M.B.
    High-resolution mass spectrometry analysis of protein oxidations and resultant loss of function.
    Biochemical Society Transactions, 36: 1037-1044, 2008.

  4. Kim, H., Cope, M., Herring, R., Robinson, G., Wilson, L., Page, G.P., Barnes, S.
    2D Difference Gel Electrophoresis of Prepubertal and Pubertal Rat Mammary Gland Proteomes.
    Journal of Proteome Research, 7 (11): 4638-4650, 2008.

  5. Prasain J.K., Jones, K., Moore, D.R., Barnes, S., Leahy, M., Roderick, R., Juliana, M.M. and Grubbs, C.J.
    Effect of cranberry juice concentrate on chemically-induced urinary bladder cancers.
    Oncology Reports 19: 1565-1570, 2008.

  6. Sarkar P, Sarkar S, Ramesh V, Kim H, Barnes S., Kulkarni A, Hall JC, Wilson BL, Thomas RL, Pellis NR, Ramesh GT.
    Proteomic Analysis of Mouse Hypothalamus under Simulated Microgravity.
    Neurochem Res. 33(11): 2335-41, 2008.

  7. Mafia K, Gupta R, Kirk M, Wilson L, Srivastava OP, Barnes S.
    UV-A-induced structural and functional changes in human lens deamidated alphaB-crystallin.
    Molecular Vision. 2008 14: 234-48, 2008.

  8. Barnes, S., Birt, D.F., Cassileth, B.R. Cefalu, W.T., Chilton, F.H., Farnsworth, N.R., Raskin, I., van Breemen, R.B., Weaver, C.M.
    Technologies and experimental approaches at the National Institutes of Health Botanical Research Centers.
    American Journal of Clinical Nutrition, 87(2): 476S-80S, 2008.

  9. Shonsey, E.M., Eliuk, S.M., Johnson, M.S., Barnes, S., Falany, C.N , Darley-Usmar, V.M. and Renfrow, M.B.
    Inactivation of human liver bile acid CoA:amino acid N-acyltransferase by the electrophilic lipid, 4-hydroxynonenal.
    Journal of Lipid Research, 49(2):282-94, 2008.

  10. Ashwell, M., Stone, E., Mathers, J., Barnes, S., Compston, J., Francis, R.M., Key, T., Cashman, K.D., Cooper, C., Khaw, K.T., Lanham-New, S., Macdonald, H., Prentice, A., Shearer, M. and Stephen, A.
    Nutrition and bone health projects funded by the UK Food Standards Agency: have they helped to inform public health policy?
    British Journal of Nutrition, 99: 198-205, 2008.

  11. Weaver, C.M., Barnes, S.,Wyss, J.M., Kim, H., Morré, D.M., Morré, D.J., Simon, J.E., Lila, M.A., Janle, E.M., Ferruzzi, M.G..
    Botanicals for age-related diseases: from field to practice.
    American Journal of Clinical Nutrition, 87(2): 493S-7S, 2008

  1. Zhang, H-G., Kim, H., Liu, C., Yu, S., Wang, J, Zhang, L., Grizzle, W.E., Kimberly, R.P., and Barnes, S.
    Curcumin reverses breast tumor exosomes mediated immune suppression of NK cell tumor cytotoxicity.
    Biochimica et Biophysica Acta, 1773: 1116-1123, 2007.

  2. Kim H, Eliuk S, Deshane J, Meleth S, Sanderson T, Pinner A, Robinson G, Wilson L, Kirk M, Barnes S.
    2D gel proteomics: an approach to study age-related differences in protein abundance or isoform complexity in biological samples.
    Methods in Molecular Biology 371:349-391, 2007.

  3. Shannon M. Eliuk, Matthew B. Renfrow, Erin M. Shonsey, Stephen Barnes, and Helen Kim.
    Active Site Modifications of the Brain Isoform of Creatine Kinase by 4-Hydroxy-2-nonenal Correlate with Reduced Enzyme Activity: Mapping of Modified Sites by Fourier Transform-Ion Cyclotron Resonance Mass Spectrometry .
    Chemical Research in Toxicology, 20:1260-1268, 2007.

  4. Prasain, J.K., Barnes, S.
    Metabolism and bioavailability of flavonoids in chemoprevention: current analytical strategies and future prospectus.
    Molecular Pharmaceutics. 4 (6), 846-864, 2007.

  5. Cheong, J.M.K., Martin, B.R., Jackson, G.J., Elmore, D., McCabe, G.P., Nolan, J.R., Barnes, S., Peacock, M., and Weaver, C.M.
    Soy isoflavones do not affect bone resorption in postmenopausal women: A dose response study using a novel approach with 41Ca.
    Journal of Clinical Endocrinology & Medicine, 92: 577-582, 2007.

  6. Prasain, J., Peng, N., Acosta, E., Moore, D.R., Arabshahi, A., Meezan, E., Barnes, S., Wyss, J.M.
    Pharmacokinetic study of puerarin in rat serum by liquid chromatography tandem mass spectrometry.
    Biomedical Chromatography, 21(4): 410 - 414, 2007.

  7. Yaozu Ye, Celia Quijano, Kristine M. Robinson, Karina C. Ricart, Amy L. Strayer, Mary Anne Sahawneh, John J. Shacka, Marion Kirk, Stephen Barnes, Mary Ann Accavitti-Loper, Rafael Radi, Joseph S. Beckman, and Alvaro G. Estevez.
    Prevention of peroxynitrite-induced apoptosis of motor neurons and PC12 cells by tyrosine-containing peptides.
    Journal of Biological Chemistry, 282: 6324-6337, 2007.

  8. Chacko, B.K., Chandler, R.T., D¹Alessandro, T.L., Mundhekar, A., Khoo, N.K., Botting, N., Barnes, S., Patel, R.P.
    Anti-inflammatory effects of isoflavones are dependent on flow and human endothelial cell PPARg.
    Journal of Nutrition, 137: 351-356, 2007.

  9. Lee, S.A., Wen, W, Xiang, Y.B., Barnes, S., Liu, D.K., Cai, Q., Zheng, W., Shu, X.O.
    Assessment of dietary isoflavone intake among middle age Chinese men.
    Journal of Nutrition, 137: 1011-1016, 2007.

  10. Prasain, J.K., Reppert, A., Jones, K., Moore, D.R., II, Barnes, S., and Lila, M.A.
    Identification of isoflavone glycosides in Pueraria lobata cultures by tandem mass spectrometry.
    Phytochemical Analysis, Phytochemical Analysis 18:50-59, 2007.

  11. C. Sites, B. Cooper, M. Toth, A. Gastaldelli, A. Arabshahi, S. Barnes
    Effect of a daily supplement of soy protein on body composition and insulin secretion in postmenopausal women.
    Fertility and Sterility, 2007.

  12. Styles NA, Falany JL, Barnes S, Falany CN.
    Quantification and regulation of the subcellular distribution of bile acid coenzyme A:amino acid N-acyltransferase activity in rat liver.
    J Lipid Res. 48(6):1305-15, 2007
  1. Poonam Sarkar, Shubhashish Sarkar, Vani Ramesh, Barbara E. Hayes, Renard L. Thomas, Bobby L. Wilson, Helen Kim, Stephen Barnes, Anil Kulkarni, Neal Pellis, and Govindarajan T. Ramesh
    Proteomic Analysis of Mice Hippocampus in Simulated Microgravity Environment
    Journal of Proteome Research, 5, 548-553, 2006.

  2. Barnes, S., Prasain, J.K., Wang, C-C., Moore, D.R., II.
    Applications of LC-MS in the study of the uptake, distribution, metabolism and excretion of bioactive polyphenols from dietary supplements.
    Life Sciences, 78(18): 2054-9, 2006.

  3. Landar, A., Giles, N.M., Oh, J-Y., Foxwell, A., Kirk, M., Barnes, S., and Darley-Usmar, V.M.
    A sensitive method for the quantitative measurement of protein thiol modification in response to oxidative stress.
    Free Radical Biology and Medicine, 40, 459-468, 2006.

  4. Horn-Ross, P.L., Barnes, S., Lee, V.S., Collins, C.N., Reynolds, P., Lee, M.M., Stewart, S.L., Canchola, A.J., Wilson, L., Jones, K.
    Reliability and Validity of an Assessment of Usual Phytoestrogen Consumption.
    Cancer Causes and Control, 17:85-93, 2006.

  5. Helen Kim, Jessy Deshane, Stephen Barnes, Sreelatha Meleth
    Proteomics analysis of the actions of grape seed extract in rat brain: technological and biological implications for the study of the actions of psychoactive compounds.
    Life Sciences 78: 2060-2065, 2006.

  6. Helen Kim, Shannon Eliuk, and Jessy Deshane, Stephen Barnes, Sreelatha Meleth
    Nutriproteomics Approach to Understanding Dementia-Relevant Brain Protein Changes in Response to Grape Seed Extract, a Dietary Antioxidant
    Oxidative Stress and Age-Related Neurodegeneration edited by Yuan Luo
    CRC Press, 2006, Chapter 26, ISBN: 0849337259

  7. Huang, C.M., Wang, C.C., Kawai, M., Barnes, S., and Elmets, C.A.
    Surfactant sodium lauryl sulfate enhances skin vaccination: Molecular characterization via a novel technique using ultrafiltration capillaries and mass spectrometric proteomics.
    Molecular & Cellular Proteomics 5:523-532, 2006.

  8. Hsu, H.C., Zhou, T., Kim, H., Barnes, S., Yang, P., Wu, Q., Zhou, J., Freeman, B.A., Luo, M., Mountz, J.D.
    Production of a novel class of polyreactive pathogenic autoantibodies in BXD2 mice causes glomerulonephritis and arthritis.
    Arthritis & Rheumatism 54: 343-355, 2006.

  9. Huang, C.M., Wang, C-C., Kawai, M., Barnes, S., Elmets, C.A.
    In vivo protein sampling using capillary ultrafiltration semi-permeable hollow fiber and protein identification via mass spectrometry-based proteomics.
    J Chromatogr A, 1109: 144-151, 2006.

  10. Barnes, S.
    In the postgenomic era, can high-dimensional analyses deliver the answers we're looking for?
    Journal of Nutrition 136: 2709S-2710S, 2006.

  11. Huang CM, Ananthaswamy HN, Barnes S, Ma Y, Kawai M, Elmets CA.
    Mass spectrometric proteomics profiles of in vivo tumor secretomes: Capillary ultrafiltration sampling of regressive tumor masses.
    Proteomics 6: 6107-6116, 2006.

  12. Prasain, J.K., Reppert, A., Jones, K., Moore, D.R., II, Barnes, S., and Lila, M.A.
    Identification of Isoflavone Glycosides in Pueraria lobata Cultures by Tandem Mass Spectrometry.
    Phytochemical Analysis, 18: 50-59, 2006.

  13. Prasain, J.K., Xu, J., Kirk, M., Smith, M., Sfakianos, J., and Barnes, S.
    Differential biliary excretion of genistein metabolites following intraduodenal and intravenous infusion of genistin in female rats.
    Journal of Nutrition, 136:2975-2979, 2006.

  14. Huang CM, Wang CC, Barnes S, Elmets CA.
    In vivo detection of secreted proteins from wounded skin using capillary ultrafiltration probes and mass spectrometric proteomics.
    Proteomics. 6(21):5805-14, 2006.

  15. Kim K, Page GP, Beasley TM, Barnes S, Scheirer KE, Allison DB.
    A proposed metric for assessing the measurement quality of individual microarrays.
    BMC Bioinformatics. 23;7:35 2006.

  16. Liu C, Yu S, Zinn K, Wang J, Zhang L, Jia Y, Kappes JC, Barnes S, Kimberly RP, Grizzle WE, Zhang HG.
    Murine mammary carcinoma exosomes promote tumor growth by suppression of NK cell function.
    The Journal of Immunology. 1;176(3):1375-85, 2006.
  1. Barnes, S., Prasain, J.K.
    Current Progress in the use of Traditional Medicines and Nutraceuticals.
    Current Opinions in Plant Biology, 8: 324-328, 2005.

  2. Allison, D.B., Cutter, G., Poehlman E.T., Moore, D.R. II, Barnes, S.
    Exactly which synephrine alkaloids does Citrus Aurantium (bitter orange) contain?
    International Journal of Obesity, 29:443-446, 2005.

  3. Cai, J., Zhao, Y., Glasier, J., Cullen, D., Barnes, S., Turner, C., and Weaver, C.
    Comparative effect of soy protein, soy isoflavones and 17β-estradiol on bone metabolism in adult ovariectomized rats.
    Journal of Bone and Mineral Research, 20: 828-839, 2005.

  4. Prasain JK, Moore DR, Barnes S, van Kuijk FJGM.
    Electrospray Tandem Mass Spectrometric Analysis of Carotenoids and their Oxidation Products.
    Journal of Mass Spectrometry, 40: 916-923, 2005.

  5. Hedlund, T.E., Maroni, P.D., Ferucci, P.G., Dayton, R., Barnes, S., Jones, R., Moore, D.R., Ogden, L.G., Wähälä, K., Sackett, H.M, and Gray, K.J.
    Long-term dietary habits influence soy isoflavone metabolism in caucasian men: selective accumulation of isoflavonoids within prostatic fluid.
    Journal of Nutrition, 135: 1400-1406, 2005.

  6. Uppala, P.T., Roy, S.K., Tousson, A., Barnes, S., Uppala, G.R., and Eastmond, D.A.
    Induction of cell proliferation and hyperploidy/polyploidy in the mammary cells of DDT- and DMBA-treated pubertal rats.
    Environmental and Molecular Mutagenesis, 46(1):43-52, 2005.

  7. Chacko, B.K., Robert Chandler, R.T., Mundhekar, A., Pruitt, H.M., Kucik, D.F., Kevil, C.G., Barnes, S., Patel, R.P.
    Revealing anti-inflammatory mechanisms of soy-isoflavones by flow: modulation of leukocyte-endothelial cell interactions.
    American Journal of Physiology, 289: H908-H915, 2005.

  8. Yang, X., Wang, J., Liu, C., Grizzle, W.E., Yu, S., Zhang, S., Barnes, S., Koopman, W.J., Mountz, J.D., Kimberly, R.P., and Zhang, H-G.
    Cleavage of p53-vimentin complex enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of rheumatoid arthritis synovial fibroblasts.
    American Journal of Pathology, 167: 705-719, 2005.

  9. Kaput, J., Ordovas, J.M., Ferguson, L., van Ommen, B, Rodriguez, R.L., Allen, L., Ames, B.N., Dawson, K., German, B., Krauss, R., Malyj, W., Archer, M.C., Barnes, S., Bartholomew, A., Birk, R., van Bladeren, P., Bradford, K.J., Brown, K.H., Caetano, R., Castle, D., Chadwick, R., Clarke, S., Clément, K., Corella. D., da Cruz, I.M., Daniel, H., Duster, T., Sven O.E. Ebbesson, S.O, Elliott, R, Fairweather-Tait, S., Felton, J., Fenech, M., Finley, J.W., Fogg-Johnson, N., Gill-Garrison, R., Gibney, M.J., Gillies, P.J., Gustafsson, J-A.,Hartman, J.L. IV, He, L., Hwang, J-K., Jang, Y., Joost, H., Junien, C., Kanter, M., Kibbe, W.A., Koletzko, B., Korf, B.R., Kornman, K., Krempin, D.W., Langin, D., Lauren, D.R., Lee, J.H., Leveille, G.A., Lin, S-J., Mathers, J., Mayne, M., McNabb, W., Milner, J.A., Morgan, P., Muller, M., Nikolsky, Y., van der Ouderaa, F., Park, T., Pensel, N., Perez-Jimenez, F., Jean-Philippe, Kaisa Poutanen, Roberts, M., Saris, W., Schuster, G., Shelling, A.N., Simopoulos, A.P., Southon, S., Tai, E.S., Towne, B, Trayhurn, P., Uauy, R., Willard J. Visek, W.J., Warden, C., Weiss, R., Wiencke, J., Winkler, J., Wolff, G.L., Zhao-Wilson, X., Zucker, J-D.
    The Case for Strategic International Alliances to Harness Nutritional Genomics for Public and Personal Health.
    British Journal of Nutrition, 94: 623-632, 2005.

  10. Meezan, E., Meezan, E.M., Jones, K., Moore II, D.R., Barnes, S., and Prasain, J.K.
    Contrasting effects of the isoflavones glucosides puerarin and daidzein on glucose metabolism in mice.
    Journal of Agricultural and Food Chemistry. 53(22):8760-7, 2005.

  11. Zakharkin S.O., Kim, K., Mehta, T., Chen, L., Barnes, S., Scheirer, K.E., Parrish, R.S., Allison, D.B., and Page, G.P.
    Sources of variation in Affymetrix microarray experiments.
    BMC Bioinformatics, 6: 214, 2005.

  12. Huang, C.M., Wang, C.C., Kawai, M., Barnes, S., and Elmets, C.A.
    Surfactant sodium lauryl sulfate enhances skin vaccination: Molecular characterization via a novel technique using ultrafiltration capillaries and mass spectrometric proteomics.
    Mass Spectrometry Reviews, 24: 647-660, 2005.

  13. Huang, C.M., Elmets, C.A., van Kampen, K.R., DeSilva, T.S., Barnes, S., Kim, H., and Tang, D.C.
    Prospective highlights of functional skin proteomics.
    Mass Spectrometry Reviews, 24: 647-660, 2005.
        This is an invited review on the application of proteomics and mass spectrometry techniques to explore the proteome of the skin in disease.

  14. Shonsey EM, Sfakianos M, Johnson M, He D, Falany CN, Falany J, Merkler DJ, Barnes S.
    Bile acid coenzyme A: amino acid N-acyltransferase in the amino acid conjugation of bile acids.
    Methods Enzymol. 400:374-94, 2005.

  15. Shonsey EM, Wheeler J, Johnson M, He D, Falany CN, Falany J, Barnes S.
    Synthesis of bile acid coenzyme a thioesters in the amino acid conjugation of bile acids.
    Methods Enzymol. 400:360-73, 2005.

  16. D'Alessandro TL, Boersma-Maland BJ, Peterson TG, Sfakianos J, Prasain JK, Patel RP, Darley-Usmar VM, Botting NP, Barnes S.
    Metabolism of phytoestrogen conjugates.
    Methods Enzymol. 2005;400:316-42, 2005.

  1. Barnes S.
    Soy isoflavones--phytoestrogens and what else?
    J Nutr. 134(5):1225S-1228S, 2004.

  2. Schuler, A.M., Barnes, S., Gower, B.A., and Wood, P.A.
    Dietary Phytoestrogens Increase Metabolic Resistance (Cold Tolerance) in Long-Chain Acyl-CoA Dehydrogenase-Deficient Mice
    Journal of Nutrition, 134:1028-1031, May 2004.

  3. Stephen Barnes and Helen Kim
    Nutriproteomics: Identifying the Molecular Targets of Nutritive and Non-nutritive Components of the Diet.
    Journal of Biochemistry and Molecular Biology, 37: 59-74, 2004.
        This review concerns how to apply proteomics and mass spectrometry to the discovery of the biologically active components of the diet.

  4. Helen Kim, PhD, Grier P. Page, PhD, and Stephen Barnes, PhD
    Proteomics and Mass Spectrometry in Nutrition Research.
    Nutrition, 20:155-165, 2004.
        This paper reviews the technologies of 2D-gel proteomics and mass spectrometry (MALDI and nanoLC-tandem mass spectrometry) as they can be applied to modern nutrition research with particular reference to experimental design. It is part of a special issue of Nutrition on nutrigenomics.

  5. Prasain, J.K., Jones, K., Brissie, N., Moore, D.R. II, Wyss, J.M., Barnes, S.
    Identification of puerarin and its metabolites in rats by liquid chromatography-tandem mass spectrometry.
    Journal of Agricultural Food Chemistry, 52: 3708-3712, 2004.
        This piece of work established a quantitative L C-MRM-MS assay for the measurement of puerarin. It was applied to studies in rats of the uptake and metabolism of this Kudzu isoflavone. It was shown that puerarin was absorbed intact and rapidly excreted in urine. It underwent minor metabolism to mono- and dihydroxylated forms as well as to daidzein and equol after 2-3 days.

  6. Foxwell, A.I., Wilson, L., Kirk, M., Coward, L., Darley-Usmar, V.M. and Barnes, S.
    Modification of cytochrome c by 4-hydroxy-2-nonenal: evidence for histidine, lysine and arginine-aldehyde adducts.
    Journal of American Society of Mass Spectrometry 15: 1136-1147, 2004.
        The reaction of cytochrome c with the reactive aldehyde 4HNE formed from oxidation of unsaturated fatty acid was studied using MALDI-TOF-MS and nanoLC-tandem mass spectrometry. Formation of up to four 4HNE adducts was discernable, three of which were fully characterized. This is the first demonstration of an arginine adduct.

  7. Prasain, J., Wang, C-C., and Barnes, S.
    Mass spectrometric methods for the determination of flavonoids in biological samples.
    Free Radical Biology and Medicine, 37: 1324-1350, 2004.
        This invited paper is an extensive review of the use of mass spectrometry for the analysis of flavonoids. It includes GC-MS, LC-MS and capillary electrophoresis-MS and MALDI-TOF, ESI, ion trap and FT-ICR techniques.

  8. Deshane, J., Chaves, L., Sarikonda, K.V, Wilson, L., Isbell, S., Kirk, M.C., Grubbs, C, Barnes, S., Meleth, S., and Kim, H.
    Proteomics Analysis of Rat Brain Protein Modulations by Grape Seed Extract
    Journal of Agricultural Food Chemistry, 52: 7872-7883, 2004.

  9. Kim, H., Hall, P., Smith, M., Kirk, M., Prasain, J.K., Barnes, S., Grubbs, C.
    Chemoprevention by grapeseed extract and genistein in carcinogen-induced mammary cancer in rats is diet-dependent.
    Journal of Nutrition, 134: 3445S-3552S, 2004.

  10. Allison DB, Barnes S, Garvey WT.
    Individual differences in the response to ingested nutrients.
    Nutrition. 20(1):1, 2004.
  1. Page G.P., Edwards J.W., Barnes S., and Allison, D.B.
    A Design & Statistical Perspective on Microarray Gene.
    Expression Studies in Nutrition - the need for playful creativity and scientific hard-mindedness.

    Nutrition, 19: 997-1000, 2003.

  2. Boersma, B.J., Patel, R.P., Benton, M.R., Kirk, M., Wilson, L.S., Botting, N.P., Barnes, S., and Darley-Usmar, V.M.
    Neutrophil myeloperoxidase chlorinates soy isoflavones and enhances their antioxidant properties.
    Free Radical Biology and Medicine, 35:1417-1430, 2003.

  3. D'Alessandro, T., Prasain, J., Botting, N.P, Moore, R., Darley-Usmar, V.M., Patel, R.P., and Barnes, S.
    Polyphenols, Inflammatory Response, and Cancer Prevention: Chlorination of Isoflavones by Human Neutrophils.
    J Nutr,133:3773S-3777S, 2003.

  4. He, D., Barnes, S, Falany, C.N.
    Rat Liver Bile Acid CoA: Amino Acid N-acyltransferase: Expression, Characterization and Peroxisomal Localization
    Journal of Lipid Research, on line September 1, 2003.

  5. Carballal, S., Radi, R., Kirk, M.C., Barnes, S., Freeman, B.A.and Alvarez, B.
    Sulfenic acid formation in human serum albumin by hydrogen peroxide and peroxynitrite.
    Biochemistry, 42: 9906-9914, 2003.

  6. Prasain, J.K., Boersma, B.J., Kirk, M., Wilson, L., Patel, R., Darley-Usmar, V.M., Botting, N. and Barnes, S.
    Mass spectrometric methods for the analysis of chlorinated and nitrated isoflavonoids: a novel class of biological metabolites..
    Journal of Mass Spectrometry, 38: 764-771, 2003.

  7. Prasain, J.K., Jones, K., Kirk, M., Wilson, L., Smith-Johnson, M., Weaver, C.M., Barnes, S.
    Profiling and quantification of isoflavonoids in kudzu dietary supplements by high-performance liquid chromatography and electrospray ionization tandem mass spectrometry.
    Journal of Agricultural Food Chemistry, 51:4213-4218, 2003.

  8. Aslan, M, Barnes, S., Kirk, M, Rosenfeld, S, Townes, T, Ryan, T and BA Freeman.
    Nitric oxide-dependent generation of reactive species in sickle cell disease: renal and hepatocellular actin tyrosine nitration.
    Journal of Biological Chemistry, 278: 4194-4204, 2003.

  9. Lanman, J., Lam, T., Barnes, S., Sakalian, M., Emmett, M.R., Marshall, A.G., and Prevelige, P.E., Jr.
    Identification of novel interactions in HIV-1 capsid protein assembly by high resolution mass spectrometry.
    Journal of Molecular Biology, 325:759-772, 2003.

  10. Belenky M, Prasain J, Kim H, Barnes S.
    DING, a genistein target in human breast cancer: a protein without a gene.
    J Nutr. 133(7 Suppl):2497S-2501S, 2003.

  11. Barnes S.
    Phyto-oestrogens and osteoporosis: what is a safe dose?
    Br J Nutr. 89 Suppl 1:S101-8, 2003.

2002

  1. Sfakianos, M., Wilson, L., Sakalian, M., Falany, C.N., and Barnes, S.
    Conserved Residues in the Putative Catalytic Triad of Human Bile Acid Coenzyme A: Amino Acid N-acyltransferase.
    Journal of Biological Chemistry, 277: 47270-47275, 2002.

  2. Falany, C.N., Xie, X, Wheeler, J.B., Wang, J., Smith, M., He, D., and Barnes, S.
    Molecular cloning and expression of rat liver bile acid CoA ligase.
    Journal of Lipid Research, 43: 2062-2071, 2002.

  3. Kim, H., Chaves, L., Mills, R., Oh, J-Y., DeSilva T., Coward, L., Kirk, M. and Barnes, S.
    Effects of soy on proteins implicated in dementias and other neurodegenerative conditions: the use of proteomics technology to assess protein changes.
    In: Soy and Health, 2002: Clinical Evidence and Dietetic Applications, Ed. Descheemaeker, K., Debruyne, I., Garant Publishers, Antwerp-Apeldoorn, pp 155-166, 2002.

  4. Barnes, S.
    New technologies in soy research. What can they bring?
    In: Soy and Health 2002: Clinical Evidence and Dietetic Applications, Ed. Descheemaeker, K., Debruyne, I., Garant Publishers, Antwerp-Apeldoorn, pp 39-50, 2002.

  5. Prasain, J., Wang, C-C., and Barnes, S.
    Mass spectrometry in the analysis of phytoestrogens in biological samples.
    In: Phytoestrogens and Health, Gilani, G.S. and Anderson, J.J., editors, AOCS Press, Champaign, IL, pp 147-177, 2002.

  6. Wang, C-C., Prasain, J., and Barnes, S.
    Review of the methods used in the determination of phytoestrogens.
    Journal of Chromatography, 777: 3-28, 2002.

  7. Barnes, S. and Messina, M.
    Introduction and Satellite Session at the Fourth International Symposium on the Role of Soy in Preventing and Treating Chronic Disease.
    Journal of Nutrition, 132: 545-546, 2002.

  8. Persky, V.W., Turyk, M.E., Wang, L., Freels, S., Chatterton, R., Jr, Barnes, S., Erdman, J., Jr, Sepkovic, D.W., Bradlow, H.L. and Potter.S.
    Effect of soy protein on endogenous hormones in postmenopausal women.
    American Journal of Clinical Nutrition. 75: 145-153, 2002.

  9. Brookes, P.S., Pinner, A., Ramachandran, A., Coward, L., Barnes, S, Kim, H., Darley-Usmar, V.M..
    High throughput two-dimensional blue-native electrophoresis: A tool for functional proteomics of mitochondria and signaling complexes.
    Proteomics 2, 969-977, 2002.

  10. Barnes S, Wang CC, Kirk M, Smith-Johnson M, Coward L, Barnes NC, Vance G, Boersma B.
    HPLC-mass spectrometry of isoflavonoids in soy and the American groundnut, Apios americana.
    Adv Exp Med Biol. 505:77-88, 2002.

  11. Lim DG, Bloodsworth A, JP Eiserich, CR White, PH Chumley, S Sweeney, M Kirk, S Barnes, VB O'Donnell, and BA Freeman.
    Nitrolinoleate – A lipid signaling molecule generated from nitric oxide and reactive oxygen species: Synthesis, characterization and biological activity.
    Proc Nat Acad Sci, 99(25):15941-15946, 2002 [doi: 10.1073/pnas.232409599]

2001

  1. Kim H, Xu J, Su Y, Xia H, Li L, Peterson G, Murphy-Ullrich J, Barnes S
    Actions of the soy phytoestrogen genistein in models of human chronic disease: potential involvement of transforming growth factor beta.
    Biochem Soc Trans. 29(Pt 2):216-22, 2001.

  2. Barnes S.
    Oestrogens and their promiscuous receptors: confronting reality.
    Biochem Soc Trans. 29(Pt 2):231-6, 20001. (Review)

  3. Barnes S.
    Role of phytochemicals in prevention and treatment of prostate cancer.
    Epidemiol Rev. 23(1):102-5, 2001. (Review)

  4. Patel, R.P., Boersma, B., Crawford, J.H., Hogg, N., Kirk, M., Kalyanaraman, B., Parks, D., Barnes, S. and Darley-Usmar, V.
    Antioxidant mechanisms of isoflavones in lipid systems: Paradoxical effects of peroxyl radical scavenging.
    Free Radical Biology and Medicine, 31:1570-1581, 2001.

  5. Whitaker, B.D., Schmidt, W.F., Kirk, M.C. and Barnes, S.
    Novel Fatty-Acid Esters of p-Coumaryl Alcohol in Epicuticular Wax of Apple Fruit.
    Journal of Agricultural Food Chemistry, 49; 3787-3792, 2001.

  6. Boersma, B., S. Barnes, M. Kirk, C-C. Wang, M. Smith, H. Kim, J. Xu, R. Patel and V.M. Darley-Usmar.
    Soy isoflavonoids and cancer - metabolism at the target site.
    Mutation Research, 480: 121-127, 2001.

  7. Zhang, C., Eiserich, J., Reiter, C, Parks, D.A., Darley-Usmar, V., Beckman, J.S., Barnes, S., Kirk, M., and White, C.R.
    L-Arginine chlorination products inhibit endothelial nitric oxide production.
    Journal of Biological Chemistry, 276: 27159-27165, 2001.

  8. Binsack, R., Boersma, B.J., Patel,, R.P., Kirk, M.C., White, C.R., Darley-Usmar, V.M., Barnes, S., Zhou, F., and Parks, D.A..
    Enhanced antioxidant activity following chlorination of quercetin by hypochlorous acid.
    Alcoholism: Clinical and Experimental Research, 25: 434-443, 2001.

  9. Tuma, R., Coward, L. Kirk, M.C., Barnes, S., and Prevelige, P.E., Jr.
    Hydrogen-deuterium Exchange as a Probe of Folding and Assembly in Viral Capsids
    Journal of Molecular Biology, 306: 389-396, 2001.

  10. Urban, D., Irwin, W., Kirk, M., Markiewicz, M.A., Myers, R., Smith, M., Weiss, H., Grizzle, W.E. and Barnes, S.
    The effect of isolated soy protein on plasma biomarkers in elderly men with elevated serum prostate specific antigen.
    Journal of Urology 165:294-300, 2001.

  11. Boersma BJ, Patel RP, Botting N, White CR, Parks D, Barnes S, Darley-Usmar VM.
    Formation of novel bioactive metabolites from the reactions of pro-inflammatory oxidants with polyphenolics.
    Biofactors.15(2-4):79-81, 2001. (Review)

2000

  1. Novak, J., Tomana, M., Kilian, M., Coward, L., Kulhavy, R., Barnes, S. and Mestecky, J.
    Heterogeneity of O-glycosylation in the hinge region of human IgA1.
    Molecular Immunology, 37: 1047-1056, 2000.

  2. Krull, R.E., Chen, P., Novak, J., Kirk, M., Barnes, S., Baker, J., Krishna, N.R. and Caufield, P.W.
    Biochemical structural analysis of the lantibiotic mutacin II.
    Journal of Biological Chemistry 275:15845-15850, 2000.

  3. Rubbo, H., Radi, R., Anselmi, D., Kirk, M., Barnes, S., Butler, J., Eiserich, J.P., and Freeman, B.A.
    Nitric oxide reaction with lipid peroxyl radicals spares -tocopherol during lipid peroxidation. Greater oxidant activity from the pair nitric oxide/ -tocopherol than -tocopherol/ascorbate.
    Journal of Biological Chemistry 275: 10812-10818, 2000.

  4. King, L. III, S. Barnes, U. Glufke, M.E. Henz, M. Kirk, K.A. Merkler, J.C. Vederas, B.J. Wilcoz, and D.J. Merkler.
    The enzymatic formation of novel bile acid primary amides. A possible class of new mammalian hormones.
    Archives of Biochemistry and Biophysics, 374: 107-117, 2000.

  5. Barnes S, Boersma B, Patel R, Kirk M, Darley-Usmar VM, Kim H, Xu J.
    Isoflavonoids and chronic disease: mechanisms of action.
    Biofactors. 12(1-4):209-15, 2000. (Review)

  6. Barnes S, Kim H, Darley-Usmar V, Patel R, Xu J, Boersma B, Luo M.
    Beyond ERalpha and ERbeta: estrogen receptor binding is only part of the isoflavone story.
    J Nutr. 130(3):656S-7S, 2000. (Review)

1999

  1. Boersma, B.J., Patel, R.P., Kirk, M., Darley-Usmar, V.M. and S.Barnes.
    Chlorination and Nitration of Soy Isoflavones.
    Archives of Biochemistry and Biophysics, 368: 265-275,1999.

  2. O'Donnell VB, Eiserich JP, Bloodsworth A, Chumley PH, Kirk M, Barnes S, Darley-Usmar VM, Freeman BA.
    Nitration of unsaturated fatty acids by nitric oxide-derived reactive species.
    Methods Enzymol. 301:454-70, 1999. (Review)

  3. O'Donnell VB, Eiserich JP, Chumley PH, Jablonsky MJ, Krishna NR, Kirk M, Barnes S, Darley-Usmar VM, Freeman BA.
    Nitration of unsaturated fatty acids by nitric oxide-derived reactive nitrogen species peroxynitrite, nitrous acid, nitrogen dioxide, and nitronium ion.
    Chem Res Toxicol. 12(1):83-92, 1999.

1998

  1. Barnes S.
    Phytoestrogens and breast cancer.
    Baillieres Clin Endocrinol Metab. 12(4):559-79, 1998. (Review)

  2. Peterson TG, Ji GP, Kirk M, Coward L, Falany CN, Barnes S.
    Metabolism of the isoflavones genistein and biochanin A in human breast cancer cell lines.
    Am J Clin Nutr. 68(6 Suppl):1505S-1511S, 1998.

  3. Coward L, Smith M, Kirk M, Barnes S.
    Chemical modification of isoflavones in soyfoods during cooking and processing.
    Am J Clin Nutr. 68(6 Suppl):1486S-1491S, 1998.

  4. Kim H, Peterson TG, Barnes S.
    Mechanisms of action of the soy isoflavone genistein: emerging role for its effects via transforming growth factor beta signaling pathways.
    Am J Clin Nutr. 68(6 Suppl):1418S-1425S, 1998. (Review)

  5. Williams JP, Jordan SE, Barnes S, Blair HC.
    Tyrosine kinase inhibitor effects on avian osteoclastic acid transport.
    Am J Clin Nutr. 68(6 Suppl):1369S-1374S, 1998.

  6. Skinner KA, White CR, Patel R, Tan S, Barnes S, Kirk M, Darley-Usmar V, Parks DA.
    Nitrosation of uric acid by peroxynitrite. Formation of a vasoactive nitric oxide donor.
    J Biol Chem. 18;273(38):24491-7, 1998.

  7. Chen P, Novak J, Kirk M, Barnes S, Qi F, Caufield PW.
    Structure-activity study of the lantibiotic mutacin II from Streptococcus mutans T8 by a gene replacement strategy.
    Appl Environ Microbiol. 64(7):2335-40, 1998.

  8. Barnes S.
    Evolution of the health benefits of soy isoflavones.
    Proc Soc Exp Biol Med. 217(3):386-92, 1998.

  9. Lamartiniere CA, Murrill WB, Manzolillo PA, Zhang JX, Barnes S, Zhang X, Wei H, Brown NM.
    Genistein alters the ontogeny of mammary gland development and protects against chemically-induced mammary cancer in rats.
    Proc Soc Exp Biol Med. 217(3):358-64, 1998.

  10. Barnes S, Coward L, Kirk M, Sfakianos J.
    HPLC-mass spectrometry analysis of isoflavones.
    Proc Soc Exp Biol Med. 217(3):254-62, 1998.

1997

  1. Barnes S.
    The chemopreventive properties of soy isoflavonoids in animal models of breast cancer.
    Breast Cancer Res Treat. 46(2-3):169-79, 1997. (Review)

  2. Crow JP, Ye YZ, Strong M, Kirk M, Barnes S, Beckman JS.
    Superoxide dismutase catalyzes nitration of tyrosines by peroxynitrite in the rod and head domains of neurofilament-L.
    J Neurochem. 69(5):1945-53, 1997.

  3. White CR, Moellering D, Patel RP, Kirk M, Barnes S, Darley-Usmar VM
    Formation of the NO donors glyceryl mononitrate and glyceryl mononitrite from the reaction of peroxynitrite with glycerol.
    Biochem J. 328 ( Pt 2):517-24, 1997.

  4. Wheeler JB, Shaw DR, Barnes S.
    Purification and characterization of a rat liver bile acid coenzyme A ligase from rat liver microsomes.
    Arch Biochem Biophys. 1348(1):15-24, 1997.

  5. Sfakianos J, Coward L, Kirk M, Barnes S.
    Intestinal uptake and biliary excretion of the isoflavone genistein in rats.
    J Nutr. 127(7):1260-8, 1997.

  6. Falany CN, Fortinberry H, Leiter EH, Barnes S.
    Cloning, expression, and chromosomal localization of mouse liver bile acid CoA:amino acid N-acyltransferase.
    J Lipid Res. 38(6):1139-48, 1997.

1996

  1. Peterson G, Barnes S.
    Genistein inhibits both estrogen and growth factor-stimulated proliferation of human breast cancer cells.
    Cell Growth Differ. 7(10):1345-51, 1996.

  2. Peterson TG, Coward L, Kirk M, Falany CN, Barnes S.
    The role of metabolism in mammary epithelial cell growth inhibition by the isoflavones genistein and biochanin A.
    Carcinogenesis. 17(9):1861-9, 1996.

  3. Murrill WB, Brown NM, Zhang JX, Manzolillo PA, Barnes S, Lamartiniere CA.
    Prepubertal genistein exposure suppresses mammary cancer and enhances gland differentiation in rats.
    Carcinogenesis. 1996 Jul;17(7):1451-7, 1996.

  4. Blair HC, Jordan SE, Peterson TG, Barnes S.
    Variable effects of tyrosine kinase inhibitors on avian osteoclastic activity and reduction of bone loss in ovariectomized rats.
    J Cell Biochem. 15;61(4):629-37, 1996.

  5. Novák J, Kirk M, Caufield PW, Barnes S, Morrison K, Baker J.
    Detection of modified amino acids in lantibiotic peptide mutacin II by chemical derivation and electrospray ionization-mass spectroscopic analysis.
    Anal Biochem. 1;236(2):358-60, 1996.

  6. Coward L, Kirk M, Albin N, Barnes S.
    Analysis of plasma isoflavones by reversed-phase HPLC-multiple reaction ion monitoring-mass spectrometry.
    Clin Chim Acta. 247(1-2):121-42, 1996.

  7. Greis KD, Hayes BK, Comer FI, Kirk M, Barnes S, Lowary TL, Hart GW.
    Selective detection and site-analysis of O-GlcNAc-modified glycopeptides by beta-elimination and tandem electrospray mass spectrometry.
    Anal Biochem. 234(1):38-49, 1996.

  8. Barnes S, Sfakianos J, Coward L, Kirk M.
    Soy isoflavonoids and cancer prevention. Underlying biochemical and pharmacological issues.
    Adv Exp Med Biol. 401:87-100, 1996.

1995

  1. Rubbo H, Parthasarathy S, Barnes S, Kirk M, Kalyanaraman B, Freeman BA.
    Nitric oxide inhibition of lipoxygenase-dependent liposome and low-density lipoprotein oxidation: termination of radical chain propagation reactions and formation of nitrogen-containing oxidized lipid derivatives.
    Arch Biochem Biophys. 324(1):15-25, 1995.

  2. Lamartiniere CA, Moore JB, Brown NM, Thompson R, Hardin MJ, Barnes S.
    Genistein suppresses mammary cancer in rats.
    Carcinogenesis. 16(11):2833-40, 1995.

  3. Barnes S.
    Effect of genistein on in vitro and in vivo models of cancer.
    J Nutr. 125(3 Suppl):777S-783S, 1995. (Review)

  4. Barnes S, Peterson TG, Coward L.
    Rationale for the use of genistein-containing soy matrices in chemoprevention trials for breast and prostate cancer.
    J Cell Biochem Suppl. 22:181-7, 1995.

  5. Wei H, Bowen R, Cai Q, Barnes S, Wang Y.
    Antioxidant and antipromotional effects of the soybean isoflavone genistein.
    Proc Soc Exp Biol Med. 208(1):124-30, 1995.

  6. Lamartiniere CA, Moore J, Holland M, Barnes S.
    Neonatal genistein chemoprevents mammary cancer.
    Proc Soc Exp Biol Med. 208(1):120-3, 1995.

  7. Barnes S, Peterson TG.
    Biochemical targets of the isoflavone genistein in tumor cell lines.
    Proc Soc Exp Biol Med. 208(1):103-8, 1995. (Review)

1994

  1. Falany CN, Johnson MR, Barnes S, Diasio RB.
    Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase.
    J Biol Chem. 269(30):19375-9, 1994.

  2. Barnes S, Peterson G, Grubbs C, Setchell K.
    Potential role of dietary isoflavones in the prevention of cancer.
    Adv Exp Med Biol. 354:135-47, 1994.

1993

  1. Lin A, Wallace RW, Barnes S.
    Purification and properties of a human platelet inositol 1,4,5-trisphosphate 3-kinase.
    Arch Biochem Biophys. 303(2):412-20, 1993.

  2. Peterson G, Barnes S.
    Genistein and biochanin A inhibit the growth of human prostate cancer cells but not epidermal growth factor receptor tyrosine autophosphorylation.
    Prostate. 22(4):335-45, 1993.

  3. Kwakye JB, Barnes S, Diasio RB.
    Identification of bile acid coenzyme A synthetase in rat kidney.
    J Lipid Res. 1993 Jan;34(1):95-9.

  4. Wei H, Wei L, Frenkel K, Bowen R, Barnes S.
    Inhibition of tumor promoter-induced hydrogen peroxide formation in vitro and in vivo by genistein.
    Nutr Cancer. 20(1):1-12, 1993.

1992

  1. Zhang R, Barnes S, Diasio RB.
    Differential intestinal deconjugation of taurine and glycine bile acid N-acyl amidates in rats.
    Am J Physiol. 262(2 Pt 1):G351-8, 1992.

  2. Zhang RW, Soong SJ, Liu TP, Barnes S, Diasio SB.
    Pharmacokinetics and tissue distribution of 2-fluoro-beta-alanine in rats. Potential relevance to toxicity pattern of 5-fluorouracil.
    Drug Metab Dispos. 20(1):113-9, 1992.

  3. Falany CN, Wheeler J, Coward L, Keehan D, Falany JL, Barnes S.
    Bioactivation of 7-hydroxymethyl-12-methylbenz[a]anthracene by rat liver bile acid sulfotransferase I.
    J Biochem Toxicol. 7(4):241-8, 1992.

1991

  1. Kwakye JB, Johnson MR, Barnes S, Grizzle WE, Diasio RB.
    Identification of bile acid-CoA: amino acid N-acyltransferase in rat kidney.
    Biochem J. 280 ( Pt 3):821-4, 1991.

  2. Peterson G, Barnes S.
    Genistein inhibition of the growth of human breast cancer cells: independence from estrogen receptors and the multi-drug resistance gene.
    Biochem Biophys Res Commun. 179(1):661-7, 1991.

  3. Johnson MR, Barnes S, Kwakye JB, Diasio RB.
    Purification and characterization of bile acid-CoA:amino acid N-acyltransferase from human liver.
    J Biol Chem. 266(16):10227-33, 1991.

  4. Sweeny DJ, Barnes S, Diasio RB.
    Bile acid conjugation pattern in the isolated perfused rat liver during infusion of an amino acid formulation.
    JPEN J Parenter Enteral Nutr. 15(3):303-6, 1991.

  5. Zhang RW, Barnes S, Diasio RB.
    Disposition and metabolism of 2-fluoro-beta-alanine conjugates of bile acids following secretion into bile.
    Biochim Biophys Acta. 1991 Apr 15;1096(3):179-86.

  6. Kwakye JB, Johnson MR, Barnes S, Diasio RB.
    A comparative study of bile acid CoA:amino acid:N-acyltransferase (BAT) from four mammalian species.
    Comp Biochem Physiol B. 100(1):131-6, 1991.

1990

  1. Johnson MR, Barnes S, Sweeny DJ, Diasio RB.
    2-Fluoro-beta-alanine, a previously unrecognized substrate for bile acid coenzyme A:amino acid:N-acyltransferase from human liver.
    Biochem Pharmacol. 40(6):1241-6, 1990.

  2. Lin AN, Barnes S, Wallace RW.
    Phosphorylation by protein kinase C inactivates an inositol 1,4,5-trisphosphate 3-kinase purified from human platelets.
    Biochem Biophys Res Commun. 170(3):1371-6, 1990.

  3. Sweeny DJ, Daher G, Barnes S, Diasio RB.
    Biological properties of the 2-fluoro-beta-alanine conjugates of cholic acid and chenodeoxycholic acid in the isolated perfused rat liver.
    Biochim Biophys Acta. 1054(1):21-5, 1990.

  4. Barnes S, Grubbs C, Setchell KD, Carlson J.
    Soybeans inhibit mammary tumors in models of breast cancer.
    Prog Clin Biol Res. 239-53, 1990.

1989

  1. Johnson MR, Barnes S, Diasio RB.
    Radioassay of bile acid coenzyme A:glycine/taurine: N-acyltransferase using an n-butanol solvent extraction procedure.
    Anal Biochem. 182(2):360-5, 1989.

  2. Barnes S, Buchina ES, King RJ, McBurnett T, Taylor KB.
    Bile acid sulfotransferase I from rat liver sulfates bile acids and 3-hydroxy steroids: purification, N-terminal amino acid sequence, and kinetic properties.
    J Lipid Res. 1989 Apr;30(4):529-40.

1988

  1. Sweeny DJ, Barnes S, Diasio RB.
    Formation of conjugates of 2-fluoro-beta-alanine and bile acids during the metabolism of 5-fluorouracil and 5-fluoro-2-deoxyuridine in the isolated perfused rat liver.
    Cancer Res. 48(8):2010-4, 1988.

1987

  1. Mukidjam E, Elgavish GA, Barnes S.
    Structure of the dysprosium-glycocholate complex in submicellar aqueous solution: paramagnetic mapping by proton nuclear magnetic resonance spectroscopy. An approximation for the intrinsic "bound" relaxation rates in the case of nondilute paramagnetic systems.
    Biochemistry. 26(21):6785-92, 1987.

  2. Hayes SM, Liu RH, Tsang WS, Legendre MG, Berni RJ, Pillion DJ, Barnes S, Ho MH.
    Enantiomeric composition analysis of amphetamine and methamphetamine by chiral phase high-performance liquid chromatography-mass spectrometry.
    J Chromatogr. 398:239-46, 1987.