Protein mass spectrometry 2008
(BMG/PHR 744)

Course will be held on Tuesdays and Fridays 9 - 11 am, January 4-March 20, 2008 in the McCallum Building, 4th floor conference room (401)


Date Lecturer Topic
Jan 4, Fri S. Barnes/H. Kim The world of biomolecules. The proteome, proteomics and other -omics and where to start [PDF File] [Questions]
Jan 8, Tue S. Barnes Methods for the identification of proteins: MALDI-TOF of proteins and peptide mass fingerprinting; LC analysis and peptide sequencing [PDF File] [Questions]
Jan 11, Fri M. Renfrow Mass spectrometry - gas phase transfer and instrumentation - include ETD [PDF File] [Questions]
Jan 15, Tu S. Barnes Ion fragmentation in mass spectrometry; application to proteomics [PDF File] [Questions]
Jan 18, Fri J. Prasain Ion Fragmentation and small molecules/metabolomics [PDF File, Questions]
Jan 22, Tu S. Barnes Separating your samples from the matrix - for the analysis [PDF File] [Questions]
  Mid-term exam - take-home
Jan 25, Fri S. Barnes Purifying proteins for mass spectrometry analysis [PDF File] [Questions]
Jan 29, Tu C. Crasto The bioinformatics of the proteome [PDF File]
Feb 1, Fri H. Kim Protein separation by electrophoresis and other 2D-methods [PDF File] [Questions]
Feb 5, Tu J. Mobley Designing the proteomics and metabolomics experiment [PDF File]
Feb 8, Fri S. Barnes Mass spectrometry in qualitative and quantitative burrowing of the proteome [PDF File] [Questions]
Feb 12, Tu J. Prasain Qualitative and quantitative analysis/method validation in metabolomics [PDF File] [Questions]
Feb 15, Fri P. Prevelige Mass Spectrometry as a Tool for Studying Protein Structure
Feb 19, Tu P. Prevelige Study of macromolecular structures - protein complexes
Feb 22, Fri S. Barnes Enzymology and mass spectrometry [PDF File] [Questions]
Feb 26, Tu M. Renfrow Analysis of protein-protein interactions by affinity purification and mass spectrometry [PDF File 1, PDF File 2, PDF File 3, PDF File 4]
Feb 29, Fri C-C. Wang Tissue and body fluid proteomics and mass spectrometry [PDF File]
Mar 4, Tu J. Mobley Tissue imaging by mass spectrometry
Mar 7, Fri M. Renfrow Applications of FT-ICR-MS and TOF imaging methodology
Mar 11, Tu J. Novak/M. Renfrow Mass spectrometry in glycomics research - Application to IgA nephropathy
Mar 14, Fri G. Hernandez Mass spectrometry and biodefense [PDF File]
Mar 17, Tu H. Kim Use of proteomics and MS methods in the study of the brain proteome and neurodegenerative diseases
Mar 20  Final report due