Annual Workshop on Metabolomics

The 6th Annual Workshop on Metabolomics was held July 22-27, 2018 on the campus of the University of Alabama at Birmingham.

The course has been jointly sponsored by the National Institute of General Medical Sciences (NIGMS) as part of the NIH Common Fund Metabolomics Initiative, and the Departments of Chemistry and Pharmacology and Toxicology at UAB.

Details on the workshop can be found on the Metabolomics Workshop web page.

Barnes elevated to Distinguished Professor

UAB Reporter
July 30, 2018

The University of Alabama System Board of Trustees awarded the rank of Distinguished Professor to five faculty during its meeting June 8.

Steve Barnes

Stephen Barnes, Ph.D., was named Distinguished Professor of Pharmacology and Toxicology in the School of Medicine. Barnes came to UAB in 1977 as a mathematical gastroenterology fellow through the National Library of Medicine and joined the faculty in 1979 as an assistant professor. Now, in addition to his position in the Department of Pharmacology and Toxicology, Barnes is a senior scientist at UAB’s Center for Free Radical Biology, Nutrition Obesity Research Center, Center for Bone and Joint Disease and Nephrology Research and Training Center and he has dual appointments in the departments of Environmental Health Sciences, Genetics and Vision Sciences.

Barnes has published more than 300 peer-reviewed journal articles, reviews and book chapters and has delivered lectures at institutions such as Vanderbilt University, Johns Hopkins University and the University of Durham in in Durham, England. In 2012, Barnes was named UAB’s Distinguished Faculty Lecturer. He also is a member of the International Science Advisory Panel at Imperial College London’s National Phenome Center.

Recent publications from TMPL

Absorbent materials to collect urine can affect proteomics and metabolomic biomarker concentrations.
Boohaker L, Halloran B, Wilson L, Berryhill T, Barnes S, Griffin R, Askenazi D.
Clin Chem Lab Med. 2018 Oct 31. pii: /j/cclm.ahead-of-print/cclm-2018-0931/cclm-2018-0931.xml. [doi: 10.1515/cclm-2018-0931] [Epub ahead of print] No abstract available. [ PMID: 30375345]

Detection of Lipid Mediators of Inflammation in the Human Tear Film
Panthi S, Chen J, Wilson L, Nichols JJ.
Eye Contact Lens. 2018 Oct 5. [doi: 10.1097/ICL.0000000000000551] [Epub ahead of print] [ PMID: 30303825]

Evaluation of a ketogenic diet for improvement of neurological recovery in individuals with acute spinal cord injury: a pilot, randomized safety and feasibility trial.
Yarar-Fisher C, Kulkarni A, Li J, Farley P, Renfro C, Aslam H, Bosarge P, Wilson L, Barnes S.
Spinal Cord Ser Cases. 2018 Sep 21;4:88. doi: 10.1038/s41394-018-0121-4. eCollection 2018. [ PMID: 30275980]

More Publications

About TMPL

The Targeted Metabolomics and Proteomics Laboratory (TMPL) is organized to provide a variety of analytical and technical services using mass spectrometry to UAB investigators. The laboratory has three mass spectrometers, a triple quadrupole instrument (SCIEX 4000), a quadrupole-linear ion trap instrument (SCIEX 6500 Qtrap), and quadrupole-TOF (SCIEX 5600 TripleTOF). The SCIEX 5600 TripleTOF is particularly powerful for comprehensive and targeted proteomics, lipidomics and metabolomics. The combination of Eksigent microflow 200 LC and 415 nanoLC with the mass spectrometers provides the highest possible sensitivity for sample analysis. The SCIEX 6500 Qtrap is fitted with a SelexION™ interface for ion mobility studies.

Contact Dr. Matt Renfrow about use of hi-resolution Orbitrap Velos instrument (renfrow@uab.edu; 205 996-4681).

A Bruker MALDI TOF-TOF instrument is available in the Comprehensive Cancer Center Core Laboratory of Dr. Jim Mobley (mobleyja@uab.edu; 205 996-6363).

New sample and data-handling arrangements in TMPL – investigators please note



MRM
Figure from J Chromatogr B Analyt
Technol Biomed Life Sci.
[ PMID: 20346741]
MRMPath
MRMPath