Welcome to Targeted Metabolomics and Proteomics Laboratory

Teaching metabolomics: a UAB outreach to researchers in sub-Saharan Africa

by Jeff Hansen

Janusz Kabarowski and SteveBarnes

For the last 10 weeks, Stephen Barnes, Ph.D., University of Alabama at Birmingham, has taught a group of master’s degree students at a university in the land-locked African nation of Mali. His outreach — via two hours of video conferencing each day and a lot of class material preparation — came at the request of the National Institute of Allergy and Infectious Diseases, to help NIAID create a cadre of bioinformatics researchers at one of the ground zeros for the deadly infectious disease malaria.

Read more at UAB News.

Loss of Merlin induces metabolomic adaptation that engages dependence on Hedgehog signaling. [doi:10.1038/srep40773]

Shamik Das, William P. Jackson, Jeevan K. Prasain, Ann Hanna, Sarah K. Bailey, J. Allan Tucker, Sejong Bae, Landon S. Wilson, Rajeev S. Samant, Stephen Barnes & Lalita A. Shevde

See full publication list.

Metabolomics - Fundamentals and Applications

Edited by Jeevan K. Prasain, ISBN 978-953-51-2854-0, Print ISBN 978-953-51-2853-3, 214 pages,
Publisher: InTech, Chapters published December 28, 2016 under CC BY 3.0 license [DOI: 10.5772/62614] Edited Volume

Metabolomics: Fundamentals and Applications authoritatively presents the basic principles and applications of metabolomics. Topics covered in this book range from the analysis of metabolites from different biological sources and their data processing and statistical analysis. This book serves as a basic guide for a wide range of audiences from less familiar with metabolomics techniques to more experienced researchers seeking to understand complex biological systems from the systems biology approach.

5th Annual Workshop on Metabolomics

July 16-21, 2017

The 5th Annual Workshop on Metabolomics will be held July 16-21, 2017 on the campus of the University of Alabama at Birmingham.

The course is jointly sponsored by the National Institute of General Medical Sciences (NIGMS) as part of the NIH Common Fund Metabolomics Initiative, and the Departments of Chemistry and Pharmacology and Toxicology at UAB.

Details on the workshop can be found on the Metabolomics Workshop web page.

Figure from J Chromatogr B Analyt
Technol Biomed Life Sci.
[PMID: 20346741]
TMPL Movie
PPT file


About TMPL

The Targeted Metabolomics and Proteomics Laboratory (TMPL) is organized to provide a variety of analytical and technical services using mass spectrometry to UAB investigators. The laboratory has three mass spectrometers, a triple quadrupole instrument (AB Sciex 4000), a quadrupole-linear ion trap instrument (AB Sciex 6500 Qtrap), and quadrupole-TOF (AB Sciex 5600 TripleTOF). The AB Sciex 5600 TripleTOF is particularly powerful for comprehensive and targeted proteomics, lipidomics and metabolomics. The combination of Eksigent microflow 200 LC and 415 nanoLC with the mass spectrometers provides the highest possible sensitivity for sample analysis.

Two fourier transform-ion cyclotron resonance instruments - supported by NCRR grants - are in the Biomedical FT-ICR Mass Spectrometry Laboratory (http://www.uab.edu/BiomedFTICR/). Contact Dr. Matt Renfrow about use of these instruments (renfrow@uab.edu; 205 996-4681).

A Bruker MALDI TOF-TOF instrument is available in the Comprehensive Cancer Center Core Laboratory of Dr. Jim Mobley (mobleyja@uab.edu; 205 996-6363).

New sample and data-handling arrangements in TMPL – investigators please note