The Department of Psychiatry and Behavioral Neurobiology

2008 - 2009

GRAND ROUNDS

 Sponsored by the UAB School of Medicine, Division of CME  
 The University of Alabama School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.  The University of Alabama School of Medicine designates this educational activity for a maximum of 1 AMA PRA Category 1 credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Archived Grand Rounds Schedules
If you need to reference past schedules or presentations, the following schedules are archived for your convenience.  
2005-2006 2006-2007 2007-2008

September 2008

The REGARDS Study: How we were seeking the causes of stroke disparities and (also) became a national longitudinal epidemiologic study of cognitive change
George Howard, DrPH
Professor of Biostatistics
School of Public Health
University of Alabama at Birmingham

Virginia J. Howard, PhD
Associate Professor of Epidemiology
School of Public Health
University of Alabama at Birmingham

Objectives: 
1. Describe the magnitude of racial and geographic disparities in stroke mortality
2. Provide an overview of the general study methods of REGARDS (i.e., the “stroke aims”), including available data domains involving depression and stress
3. Provide a history of how cognitive assessment was added to the study, and describe the research protocol.
4. Describe distributions and predictors of selected cognitive measures
5. Discuss opportunities for collaboration

References:
Howard G: Why do we have a stroke belt in the southeastern United States? A review of unlikely and uninvestigated potential causes. Am J Med Sci 1999;317:160-167.

Howard VJ, Cushman M, Pulley L, Gomez C, Go R, Prineas RJ, Graham A, Moy CS, Howard G. The Reasons for Geographic And Racial Differences in Stroke (REGARDS) Study: Objectives and Design. Neuroepidemiology 2005;25:135–143.

Wadley V, McClure LA, Howard VJ, Unverzag FW, Go RC, Moy CS, Crowther, MR, Gomez CR, Howard G. Cognitive status, stroke symptom reports, and modifiable risk factors among individuals with no diagnosis of stroke or TIA in the REasons for Geographic and Racial Differences in Stroke (REGARDS) Study. Stroke 2007;38:1143–47.

Sept. 23
11:00am

Glycogen synthase kinase-3 (GSK3): a potential therapeutic target to treat neuroinflammation
Patrizia De Sarno, Ph.D.
Instructor, Behavioral Neurobiology
Department of Psychiatry and Behavioral Neurobiology
University of Alabama School of Medicine

Objectives: 
1. To investigate the role of GSK3 in neuroinflammation using the mouse model of experimental autoimmune encephalomyelitis.
2. Determine whether inhibiting GSK3 with lithium is a potential target for therapy of multiple sclerosis and other autoimmune inflamatory diseases affecting the CNS.

References:
De Sarno, P., Axtell, R.C., Raman, C., Roth, K.A., Alessi, D.R., and Jope, R.S. Lithium prevents and ameliorates experimental autoimmune encephalomyelitis (EAE). J. Immunol. 2008, 181: 338-345.

Autism: Cortex, Cognition and Connectivity
Dr. Rajesh Kana
Assistant Professor
Department of Psychology
University of Alabama at Birmingham

Objectives:
1. The audience will acquire a basic understanding of the brain structure and functioning in autism.
2. The audience will gain knowledge about the neutral basis of behavioral and cognitive characteristics in people with autism

Due to HIPPA policy, this Grand Rounds is closed to outside professionals.  Only UASOM Department of Psychiatry faculty, staff, residents, and medical students on rotation can attend.

Case Conference
Norman Huggins, M.D. and panel
Assistant Professor
Department of Psychiatry and Behavioral Neurobiology
University of Alabama School of Medicine

Biology of schizophrenia: genes, models, and phenotypes
Akira Sawa, M.D., Ph.D.
Associate Professor of Psychiatry
Director, Program in Molecular Psychiatry
Department of Neuroscience
The Johns Hopkins University

Objectives:
To overview how genetic studies can contribute to understanding of mechanisms for schizophrenia and good clinical practice.

References:
Sawa, A. & Snyder, S. H. Schizophrenia: diverse approaches to a complex disease. Science 296, 692–695 (2002).

A. Kamiya, K. Kubo, T. Tomoda, M. Takaki, R. Youn, Y. Ozeki, N. Sawamura, U. Park, C. Kudo and M. Okawa et al., A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex developmen

t, Nat Cell Biol 7 (2005), pp. 1167–1178.

Atsushi Kamiya, Perciliz L. Tan, Ken-ichiro Kubo, Caitlin Engelhard, Koko Ishizuka, Akiharu Kubo, Sachiko Tsukita, Ann E. Pulver, Kazunori Nakajima, Nicola G. Cascella, Nicholas Katsanis, and Akira Sawa, Recruitment of PCM1 to the Centrosome by the Cooperative Action of DISC1 and BBS4: A Candidate for Psychiatric Illnesses Arch Gen Psychiatry, Sep 2008; 65: 996 - 1006.
 

The Role of the Pharmaceutical/Device Industry in the Academic Medical Center

A Discussion with:
Thomas Stewart Huddle, M.D., Associate Professor, General Internal Medicine
Stuart James Cohen, M.D., Associate Professor, General Internal Medicine
Rayford W. Thweatt, M.D., Professor, Department of Psychiatry & Behavioral Neurobiology
Meza Kelley, LCSW, Assistant Professor, Department of Psychiatry & Behavioral Neurobiology
Nathan B. Smith, M.D., Professor, Department of Psychiatry & Behavioral Neurobiology

Moderated by Daniel Dahl, M.D., Associate Professor, Department of Psychiatry & Behavioral Neurobiology

Link to discussion format and questions

North American Psychiatric Resident Wellness Survey
Paul O'Leary, M.D. 
Sub-specialty Resident in Child/Adolescent Psychiatry
Department of Psychiatry and Behavioral Neurobiology
University of Alabama School of Medicine

Objectives: 
1. Discuss differences between the stressed and relaxed residents, including work hours, coping mechanisms, and mental health.
2. Discuss what coping mechanisms the residents use.
3. Discuss the main stressors of psychiatric residents

References:
Woodside J, Miller M, Floyd M, McGowen R, Pfortmiller D: Observations on Burnout in Family Medicine and Psychiatry Residents. Academic Psychiatry 2008; 32:13-19.

Keim SM, Mays MZ, Williams JM, Serido J, Harris RB: Measuring wellness among resident physicians. Medical Teacher, Vol. 28, No. 4, 2006, pp. 370-374.
 

November 2008

Objectives:
1. To provide a conceptual framework for the study of engagement in HIV care that may be applicable to other chronic diseases.
2. To describe the prevalence and implications of mental health and substance use disorders in HIV-infected patients, particularly as it pertains to engagement in care.

References:    Journal titles link to abstract and/or full text
1.  Engaging HIV-Infected Patients in Care:  Their Lives Depend on It  Clin Infect Dis. 2007 Jun 1;44(11):1500-2. Epub 2007 Apr 23.
2.  Minorities, the Poor, and Survivors of Abuse:  HIV-Infected Patients in the US Deep South  South Med J. 2007 Nov;100(11):1114-22
3.  Relation of Lifetime Trauma and Depressive Symptoms to Mortality in HIV  Am J Psychiatry 164:1707-1713, November 2007
4.  Barriers to Antiretroviral Adherence: The Importance of Depression, Abuse, and OtherTraumatic    Events  AIDS Patient Care STDS. 2006 Jun;20(6):418-28.

The CATIE Trial: The Data and the Controversy
Marvin S. Swartz, M.D.
Professor and Head, Division of Social and Community Psychiatry
Executive Vice Chair, Department of Psychiatry and Behavioral Sciences
Director, Duke Area Health Education Center Program (AHEC)
Duke University Medical Center

Objectives:
1)  Review the findings from the CATIE trial to date
2)  Discuss implications of the findings for practice
3)  Examine the controversies about the findings

References:
Lieberman JA, Stroup TS, McEvoy JP, Swartz MS, Rosenheck RA Perkins DO, Keefe RSE, Davis SM, Dadvis CE, Lebowitz BD, Severe J, Hsiao JK. Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. The New England Journal of Medicine 2005; 353(12):1209-1223.
 
Swartz MS, Stroup TS, McEvoy JP, Davis SM, Rosenheck RA, Keefe RSE, Hsiao JK, Leiberman JA for the CATIE Investigators.  What CATIE Found: Results from the NIMH Schizophernia Trial.  Psychiatric Services 2008; 59(5):500-506.

NO GRAND ROUNDS SCHEDULED
THANKSGIVING HOLIDAY

December 2008 

 Dangerousness Decisions: Does Possible Violence Justify Involuntary Confinement?
Douglas Mossman, M.D.
Director, Glenn M. Weaver Institute of Law and Psychiatry
University of Cincinnati College of Law
Volunteer Professor and Associate Program Director, Institute of Psychiatry and Law
University of Cincinnati College of Medicine

Objectives:
At the conclusion of this presentation, attendees will
1) summarize the events leading to the Tarasoff decision,
2) summarize the requirements Tarasoff imposed,
3) describe current limitations of violence assessment,
4) describe ethical problems posed by preventive detention.

References:
Mossman D: Assessing predictions of violence: being accurate about accuracy. J Consulting Clin Psychology 1994;62:783-792
 
Mossman D: Critique of pure risk assessment, or Kant meets Tarasoff. U Cincinnati L Rev 2006;75:523-609

Objectives:  
1) Familiarize participants with the clinical challenges associated with opioid analgesic abuse among patients with chronic non-cancer pain; 
2) Provide an overview of findings of a treatment trial for patients with pain and opioid use disorders.

References:
Heit HA. The truth about pain management: the difference between a pain patient and an addicted patient. Eur J Pain, 2001, 5(Suppl A), 27-9.
 
Savage SR. Long-term opioid therapy: Assessment of consequences and risks. J Pain and Symptom Management 1996, 11, 274-86.
 
Weaver M, Schnoll S. Abuse liability in opioid therapy for pain treatment in patients with an addiction history. Clin J Pain 2002, 18(4 Suppl):S61-9.
 

Objectives:

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2008/2009 GRAND ROUNDS
"The University of Alabama School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.  The University of Alabama School of Medicine designates this educational activity for a maximum of 1 hour in category 1 credit toward the AMA Physician's Recognition Award. Each physician should claim only those hours of credit that he/she actually spent in the activity."

January 2009     February 2009     March 2009     April 2009      May 2009

January 2009

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TBA
Rebecca Jones, M.D.
PGY-IV Resident in Psychiatry
Department of Psychiatry and Behavioral Sciences
University of Alabama School of Medicine

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 February 2009

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March 2009

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Mar. 17
11:00am

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 April 2009

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Third Annual Research Symposium
Grand Rounds Series

The University of Alabama School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.  The University of Alabama School of Medicine designates this educational activity for a maximum of 2 AMA PRA Category 1 credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Apr. 21
   8:30-
   12:00

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TBA
Evan Grant, M.D.
PGY-IV Resident in Psychiatry
Department of Psychiatry and Behavioral Sciences
University of Alabama School of Medicine

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May 2009

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May 19
11:00am

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Fourteenth Annual Scholar's Bowl  
Moderated by Daniel C. Dahl, M.D.
Associate Professor, Vice Chairman for Education and Training & Clinical Affairs  
Residency Training Director 
Department of Psychiatry and Behavioral Neurobiology
University of Alabama School of Medicine

A rapid-pace, information-packed hour of questions in which a two teams of our residents and faculty will compete against each other for the title of Scholar's Bowl Champions of 2008.  Dr. Dahl will serve as moderator and will provide a series of challenging psychiatric as well as general knowledge questions.   You won't want to miss it! 

Objectives: 
To stimulate review of the Psychiatric literature and the Psychiatry Resident In-Training Examination (PRITE) material.

"The University of Alabama School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.  The University of Alabama School of Medicine designates this educational activity for a maximum of 1 hour in category 1 credit toward the AMA Physician's Recognition Award. Each physician should claim only those hours of credit that he/she actually spent in the activity."

Questions or  comments concerning these activities?  Write, Call, FAX, or E-mail: 

Carol Schaffhausen, B.S.
The University of Alabama at Birmingham
Eye Foundation Hospital
Psychiatry - 3rd Floor
1720 University Blvd.
Birmingham, AL 35233
PHONE 934-1307  FAX 934-4659  cschaff@uabmc.edu

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