• Cystic Fibrosis (CF) Animal Models Core
    Cystic Fibrosis (CF) Animal Models Core

    Director: David M. Bedwell, Ph.D.
    Email: dbedwell@uab.edu
    Phone: 934-6593

    Website:  http://www.uab.edu/cfcenter

    The mission of the Animal Models Core is to generate and provide murine and other models for the study of cystic fibrosis.  Mouse line generation by both oocyte micro-injection and embryonic stem cell gene targeting technologies are assisted by the Core.  The Mouse Models Core also establishes breeding colonies of CF mice, and genotypes and provides these to UAB investigators.

    If you have any questions please contact us at:  GFJCFRC@uab.edu

    Core capabilities include:

    • CF Mouse and Other Animal Models
    • Murine nasal potential difference
    • Chloride secretion perfusion protocol
    • Sodium absorption protocol
    • Bronchoalvelolar lavage analysis