Objectives

The objectives of the core are to provide:

  1. Body composition: Whole-body composition analysis by chemical carcass analysis, dual-energy X-ray absorptiometry (DXA), quantitative magnetic resonance (QMR), and micro-computed tomography (µCT)
  2. Energy balance: Comprehensive assessments of metabolic rate (indirect calorimetry), food intake, fecal output, activity, and body temperature
  3. Glucose homeostasis: Glucose and insulin tolerance testing
  4. Cardiovascular assessment: Echocardiography and blood pressure
  5. Imaging:  Bioluminescence and fluorescence imaging and gamma-ray imaging, including SPECT
  6. Transgenic animal models: Assistance with construct preparation, generation of transgenic/knock-out mice, husbandry and colony management, and genotyping