Recent and Selected Publications (from complete bibliography):

Patel P, Kearney JF. Immunological Outcomes of Antibody Binding to Glycans Shared between Microorganisms and Mammals. Journal of Immunology 2016 Dec 1;197(11):4201-4209. Review. Abstract

Patel PS, King RG, Kearney JF. Pulmonary α-1,3-Glucan-Specific IgA-Secreting B Cells Suppress the Development of Cockroach Allergy. Journal of Immunology 2016 Oct 15;197(8):3175-3187. Erratum in: Journal of Immunology 2016 Dec 15;197(12 ):4861.  Abstract

New, J.S., King, R.G., and Kearney, J.F.  Manipulation of the glycan-specific natural antibody repertoire for immunotherapy.  Immunological Reviews: 2016; 270(1): 32-50.  Abstract

Patel, P.S. and Kearney, J.F.  Neonatal exposure to pneumococcal phosphorylcholine modulates the development of house dust mite allergy during adult life.  Journal of Immunology: 2015; 194(12): 5838-50.  Abstract

Wharton, R.E., Stefanov, E.K., King, R.G., and Kearney, J.F.  Antibodies generated against Streptococci protect in a mouse model of disemminated aspergillosis.  Journal of Immunology: 2015; 194(9): 4387-96.  Abstract

Kearney, J.F., Patel, P., Stefanov, E.K., King, R.G.  Natural antibody repertoires: development and functional role in inhibiting allergic airway disease.  Annual Review of Immunology: 2015; 33:475-504.  Abstract

Vale, A.M., Kapoor, P., Skibinski, G.A., Elgavish, A., Mahmoud, T.I., Zemlin, C., Zemlin, M., Burrows, P.D., Nobrega, A., Kearney, J.F., Briles, D.E., Schroeder, H.W., Jr.  The link between antibodies to OxLDL and natural protection against pneumococci depends on D(H) gene conservation.  The Journal of Experimental Medicine: 2013; 210(5):875-90.  Abstract

Kin, N.W., Stefanov, E.K., Dizon, B.L.P., Kearney, J.F.  Antibodies generated against conserved antigens expressed by bacteria and allergen-bearing fungi suppress airway disease.  J Immunol: 2012 Sep 1; 189 (5), 2246-2256.  Abstract

Foote, J.B., Mahmoud, T.I., Vale, A.M., Kearney, J.F.  Long-term maintenance of polysaccharide-specific antibodies by IgM-secreting cells.  J Immunol: 2012 Jan 1; 188(1): 57-67. Epub 2011 Nov 23.  Abstract

Mahmoud, T.I., Schroeder, H.W., Jr., Kearney, J.F.  Limiting CDR-H3 diversity abrogates the antibody response to the bacterial polysaccharide alpha-1,3 dextran.  J Immunol: 2011 Jul 15; 187(2): 879-86.  Epub 2011 Jun 15.  Abstract

Foote, J.B., and Kearney, J.F. Generation of B Cell memory to the bacterial polysaccharide alpha 1-3 dextran. J Immunol: 183:6359-6368, 2009.  Abstract

Mahmoud, T.I., Kearney, J.F.
Terminal deoxynucleotidyl transferase is required for an optimal response to the polysaccharide alpha-1,3 dextran.  J Immunol: 2010 Jan 15;184(2):851-8. Epub 2009 Dec 16.  Abstract

Balazs, M., Martin, F., Zhou, T., and Kearney, J.F. Blood dendritic cells interact with splenic mariginal zone B cells to initiate T-independent immune responses. Immunity 17(3):341-52, Sep, 2002. Abstract

Martin, F. and Kearney, J.F. Marginal-zone B cells. Nature Reviews Immunology 2(5):323-35, May 2002. Abstract

Thai, T.H., Purugganan, M.M., Roth, D.B., and Kearney, J.F. Distinct and opposite diversifying activities of terminal transferase splice variants. Nat. Immunol. 3(5):457-62, May 2002. Abstract

Benedict, C.L., Gilfillan, S., and Kearney, J.F. The long isoform of terminal deoxynucleotidyl transferase enters the nucleus and, rather than catalyzing nontemplated nucleotide addition, modulates the catalytic activity of the short isoform. J. Exp. Med. 193:89-99, 2001. Abstract

Martin, F., Oliver, A.M., and Kearney, J.F. Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens. Immunity 14:617-629, 2001. Abstract

Martin, F. and Kearney, J.F. Positive selection from newly formed to marginal zone B cells depends on the rate of clonal production, CD19, and btk. Immunity 12(1):39-49, 2000. Abstract

Benedict, C.L. and Kearney, J.F. Increased junctional diversity in fetal B cells results in a loss of protective anti-phosphorylcholine antibodies in adult mice. Immunity 10:607-617, 1999. Abstract

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