Heflin Center for Human Genetics (University-Wide Interdisciplinary Research Center)
Director: Jan P. Dumanski, PhD
Established: October 2001

Mission
The multi-school, multi-departmental Heflin Center for Human Genetics was established to serve as a centerpiece of the UAB Genetics Initiative. The mission of the Center is to bring together the UAB community of genetic investigators and to develop a robust technologic infrastructure to support genetic and genomic research at UAB.

Center Research
Housed in the Kaul Human Genetics Building, the Genomics Core has established three high-priority technological resources: 1) microarray analyses on multiple levels (expression, gene dosage and methylation profiling), 2) high-throughput sequencing, and 3) high-throughput genotyping, including single nucleotide polymorphisms (SNPs). Data management is supported by the UAB Molecular and Genetic Bioinformatics Facility (MGBF), which has been incorporated into the Center, and statistical support is provided through a collaborative arrangement with the Section on Statistical Genetics in the Department of Biostatistics.

Jan Dumanski, PhD (Department of Genetics) serves as Director of the Heflin Center. Michael Crowley, PhD is Director of the Center's Genomics Core and is responsible for overseeing the development of the technologic infrastructure and its day-to-day operations.

Education and Training Activities
The Genetics and Genomics Research seminar series, the Mouse Genomics Working Group, the Quantitative Trait Locus (QTL) Study Group and targeted educational workshops (e.g., Statistical Genetics for the Biomedical Investigator) provide opportunities for learning and collaborations within the Center.

For additional information:

Director: Jan P. Dumanski, PhD
Email: dumanski@uab.edu

Associate Director: Lisa Guay-Woodford, MD
Email: lgw@uab.edu

Co-Director, Michael Crowley, PhD, Principal Area of Responsibility: Genomics
Core Facility
Email: mcrowley@uab.edu
Phone: 205-975-2013

Co-Director, Carl Bruder, PhD, Principal Area of Responsibility: Microarray
Printing Core Facility
Email: cbruder@genetics.uab.edu
Phone: 205-996-4037

Web Site: http://www.heflingenetics.uab.edu/home/index.shtml


Approved by: Jan P. Dumanski, PhD, Director
Date: April 18, 2007


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