Richard A Dluhy. Professor and Chair
email
Chemistry Building 201C
(205) 975-5381

Research and Teaching Interests: Bioanalytical and Biophysical Vibrational Spectroscopy and Imaging, Nanotechnology-based Plasmonics for Biomedical Sensing

Office Hours: By appointment

Education:
  • BS, University of Connecticut, Biochemistry
  • PhD, Rutgers University, Physical Chemistry

I am originally from the New York City area and received my education in the northeast, at the University of Connecticut (BS) and Rutgers University (PhD). I then moved even further north as a post-doctoral research associate at the National Research Council of Canada in Ottawa, Canada. Prior to starting in academics, I worked in the pharmaceutical industry at Hoffman-LaRoche (Nutley, NJ), and in the biotechnology group at Battelle Memorial Institute (Columbus, Ohio).

Since 1990, my family and I have lived in the south, where I was a Professor in the Department of Chemistry at the University of Georgia (Athens). At UGA I was also the Associate Department Head and Director of the Nanoscale Science and Research Center. In 2015 I moved to UAB as the Chair of the Department of Chemistry.

My research work is in the area of bioanalytical spectroscopy; it has been supported by the National Institutes of Health, National Science Foundation, Howard Hughes Medical Institute, US Department of Energy, and the European Union. I like to teach a variety of courses, everything from first year freshman seminars to advanced graduate courses. In my spare time I can been seen struggling to bicycle up some of the (steep!) hills around Birmingham, or attempting to keep my motorcycle upright while investigating the interesting back roads of Alabama.

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My research program is in the application of nanoscience and nanotechnology to bioanalytical problems. With the assistance of students, post-docs, and others, we are developing new surface spectroscopic methods for nano-optical detection in biomedical diagnostics. We are particularly interested in nanofabrication and analysis methods that use surface-enhanced Raman spectroscopy (SERS) as the optical read-out technique. SERS provides specific and quantitative information about biomedically important pathogens, including viruses and bacteria. We are developing new multivariate computational methods for the analysis of vibrational spectra. Our research interests also cover a range of topics related to surface and interfacial analysis, especially the use of infrared and Raman spectroscopy for the study of molecularly engineered surfaces for potential applications such as sensors or biomaterials, as well as the spectroscopic and microscopic imaging of surfaces and interfaces.
  • Henderson, K. C.; Benitez, A. J.; Ratliff, A. E.; Crabb, D. M.; Sheppard, E. S.; Winchell, J. M.; Dluhy, R. A.; Waites, K. B.; Atkinson, T. P.; Krause, D. C. Specificity and Strain-typing Capabilities of Nanorod Array-Surface Enhanced Raman Spectroscopy for Mycoplasma pneumoniae Detection. PloS One 2015, 10(6), e0131831. DOI: 10.1371/journal.pone.0131831.
  • Rivera-Betancourt, O. E.; Sheppard, E. S.; Krause, D. C.; Dluhy, R. A. Layer-by-Layer Polyelectrolyte Encapsulation of Mycoplasma pneumoniae for Enhanced Raman Detection. Analyst 2014, 139(17), 4287-95.
  • Negri, P.; Choi, J.-Y.; Jones, C. A.; Tompkins, S. M.; Tripp, R. A.; Dluhy, R. A. Identification of Virulence Determinants in Influenza Viruses. Analytical Chemistry 2014, 86(14), 6911-17.
  • Rivera-Betancourt, O. E.; Karls, R.; Grosse-Siestrup, B.; Helms, S.; Quinn, F.; Dluhy, R. A. Identification of Mycobacteria Based on Spectroscopic Analyses of Mycolic Acid Profiles. The Analyst 2013, 138, 6774-85.
  • Negri, P.; Dluhy, R. A. Detection of Genetic Markers Related to High Pathogenicity in Influenza by SERS. The Analyst 2013, 138, 4877-84.
  • Negri, P.; Dluhy, R. A.; Ag Nanorod Based Surface-Enhanced Raman Spectroscopy Applied to Bioanalytical Sensing. Journal of Biophotonics 2013, 6(1), 20-35.
  • Negri, P.; Kage, A.; Nitsche, A.; Naumann, D.; Xu, B.; Dluhy, R. A. Direct Optical Detection of Viral Nucleoprotein Binding to an Anti-Influenza Aptamer. Analytical Chemistry 2012, 84(13), 5501-8.
  • Negri, P.; Kage, A.; Nitsche, A.; Naumann, D.; Dluhy, R. A. Detection of viral nucleoprotein binding to anti-influenza aptamers via SERS. Chemical Communications 2011, 47(30), 8635-37.
  • Research Scientist, Hoffman-LaRoche, Inc., Nutley, New Jersey
  • Chemist, GAF Corporation, Wayne, New Jersey
  • Research Assistant, Department of Chemistry, Rutgers University
  • Postdoctoral Research Associate, Division of Chemistry, National Research Council of Canada, Ottawa, Ontario, Canada
  • Senior Research Scientist, Battelle Memorial Institute, Columbus, Ohio
  • Associate Professor and Professor, Department of Chemistry, University of Georgia, Athens, Georgia
  • Associate Department Head, Department of Chemistry, University of Georgia
  • Director, Nanoscale Science and Engineering Center, University of Georgia
  • Co-Founder and President, Argent Diagnostics, Inc., Athens, Georgia
  • Professor and Chair, Department of Chemistry, University of Alabama at Birmingham, Birmingham, Alabama
  • H. Martin Freeman Graduate Student Award, Rutgers University
  • Rutgers University Graduate Student Award for Research Excellence
  • G.E. Philbrook Award for Outstanding Undergraduate Teaching, Northeast Georgia Section of the American Chemical Society
  • Professeur Visité, Centre de Physique Moléculaire Optique et Hertzienne, Université Bordeaux, Bordeaux, France
  • Alexander von Humboldt - Friedrich Wilhelm Bessel Research Award, Alexander von Humboldt Foundation, Bonn, Germany
  • Visiting Research Scientist, Max Planck Institut für Kolloid und Grenzflächenforshung, Potsdam, Germany
  • Research Fellow, Deutscher Akademischer Austausch Dienst (DAAD), Bonn, Germany
  • Visiting Research Scientist, Robert Koch Institut, Berlin, Germany
  • Fellow, Society for Applied Spectroscopy