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Our drug discovery and development capacity supports efforts through a robust program of competitive pilot programs to develop high-throughput assays, library screens and medicinal chemistry. A robust capacity is also available for biophysical analyses.

The Alabama Drug Discovery Alliance is a collaboration between the UAB School of Medicine and Southern Research, with the UAB CCTS and the UAB Comprehensive Cancer Center being crucial contributors to its inception. The alliance's objective is to facilitate drug discovery and development by supporting pilot projects with a portfolio of services tailored to meet individual needs.  Learn more >

This facility provides advice and consultation useful in structural biology and drug design and discovery efforts including: quality control in synthetic and medicinal chemistry drug discovery/design; determination of 3D structures of proteins and their complexes; protein complexes with low molecular weight compounds; STD-NMR screening; fragment-based discovery and design (lead optimization); membrane proteins in solution; and NMR of cells.  Learn more >

This shared facility offers pre-clinical and clinical trial design for pharmacokinetic/pharmacodynamic (PK/PD) analyses and sample analysis for drug and/or metabolite quantitation. It also offers assistance with data analysis and interpretation.  Learn more >

Southern Research is a not-for-profit, 501(c)(3) organization conducting basic and applied research in the areas of drug discovery, preclinical drug development, advanced engineering, and environmental protection. It discovered more than 20 drugs that have entered clinical trials and 7 drugs that have been approved by the FDA for use in the treatment of cancer - a record surpassing that of any other organization. Due in part to its extensive combinatorial chemistry library, Southern Research is a member of the national Molecular Libraries Screening Centers Network.  Learn more >