Pilot Impact Box 3


The CCTS serves a regional population heavily burdened with cardiometabolic, vascular, and cancer-related diseases. Through the CCTS Interdisciplinary Network Pilot Program, we seek to (a) ameliorate disparities in these and other conditions that disproportionally affect minority and special populations across the CCTS Partner Network and (b) develop the future translational research workforce in a spirit that fosters collaboration, team science, and innovative discovery. 


The CCTS invites proposals that address scientific questions consistent with the Center’s mission at any “stage of research along the path from the biological basis of health and disease to interventions that improve the health of individuals and the public” as described in NCATS’ Translational Science Spectrum

Important Note: The CCTS Mission defines the concept of health disparities more broadly than “vulnerable groups” or “underserved populations.” CCTS characterizes such differences in health and health outcomes by considering multiple dimensions, including ancestry (race, ethnicity), biology (genetic admixture), geography (urban, rural), age (young, aged), or socioeconomics (education, income). 

To be responsive to the CCTS Pilot Program’s RFA, projects should be set in the context of health conditions that disproportionately affect our region based on one or more of these considerations. The study design may, but is not required to, compare two dimensions. A project may also attempt to better understand the biologic mechanism that may influence such differential outcomes.

Please consult the 2020 Request for Applications (RFA) for all instructions and guidelines before submitting your application to the CCTS Interdisciplinary Network Pilot Program. 

Special Consideration

For the 2020 pilot awards, special consideration will be given to projects that:

  • bring together investigators across two or more partner institutions
  • investigate the operational principles underlying each step of the translational process
  • address scientific questions of particular importance to the health of our communities, including health disparities, health challenges across the life course (e.g., premature birth, pediatrics, geriatrics), health literacy and/or numeracy, and environmental factors related to health and/or
  • involve community-engaged research, population health investigation or innovative approaches to promote efficiency in participant recruitment to clinical studies


Posted Date July 16, 2019  
Open Date (Earliest Submission Date) July 22, 2019                                      
Pre-Application Due Date August 14, 2019, 5pm CT  - Extended to Oct. 21** -  
Full Application Invitations November 1, 2019  
Full Application Due Date (invitation required) December 20, 2019, 5pm CT**  
Scientific Merit Review January 2020  
Advisory Council & NIH Review April 2020  
Orientation Meeting for Awardees April 15, 2020  
Earliest Start Date May 1, 2020  
Expiration Date April 30, 2021  
*some dates may vary as a result of unanticipated delays | ** no additional deadline extensions in 2019

Two-Phase Application Process

All instructions and guidelines for submitting an application to the CCTS Interdisciplinary Network Pilot Program are included in the 2020 RFA. We strongly encourage applicants to consult the RFA prior to beginning the application process. 

1. Pre-Application
A pre-application is required by this mechanism. Pre-applications will be scored on the NIH 9-point scale. Investigators with the highest scored proposals will be invited to submit a full application. Submissions are accepted through the CCTS Pilot Program REDCap Submission Form. Please note that Chrome is the preferred browser for this web-based application.

2. Full Application
The Full Application online submission form link will be shared with those investigators invited to submit a full application. Applicants will work with expert consultants and peer reviewers to sharpen their science prior to Full Application submission.

Award announcements are anticipated on May 1, 2020.

To hear about these and other funding opportunities, subscribe to our CCTS Digest.