Amm Lab

Two researchers in a lab working with equipment.

PI Name: Hope M. Amm, Ph.D.
Research Focus: Dr. Amm’s research focuses on oral tumors, including odontogenic tumors and squamous cell carcinomas. Her long term research goal is to conduct translational research to elucidate cellular signaling within human tumors and cancers for the development of better diagnostics and treatments.

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Biofilm and Microbiome Laboratory

Hui Wu head shot.

PI Name: Hui Wu
SOD Research Theme: Infection and Host Response
Research Focus: Biofilm and Microbiome in Health and Disease; Microbiota-targeted precision therapy

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Biomaterials Research Lab

Dentist examining patient's mouth with 3D model of teeth on a screen behind him.

PI Name: Nathaniel Lawson
SOD Research Theme: Biomaterials
Research Focus: We perform mechanical, optical, and some biologic property testing for dental materials. We perform mostly contracted research for dental manufacturers to help in the development process of new products, optimize the performance of dental materials, assist with the creation of instructions for use, and compare new products to existing products.

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Hassan Lab

Two researchers in a lab looking at a computer screen.

PI Name: Quamarul Hassan
SOD Research Theme: Craniofacial Development/Genetics
Research Focus: We are seeking to understand genetic changes that occur during the maturation of the bone building cells, osteoblasts. Specifically, we study the epigenetic controls that drive osteoblast differentiation from their parent stem cell population. We perform these studies in mouse models to identify how epigenetic modulators affect bone density, physiology, and structure.

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Javed Lab

Model of mice skeletons.

PI Name: Amjad Javed
SOD Research Theme: Craniofacial Genetics and development, Biomaterial and Biomimetic
Research Focus: The central focus of our laboratory is to understand the molecular mechanisms that govern the formation and remodeling of skeletal tissues such as Cartilage, Bone, Teeth, and Tendon. Skeletal cell differentiation involves the stepwise establishment of specific genetic programs in mesenchymal stem cells. We are exploring the signaling role of runt related transcription factor (Runx), and Specificity protein 7 (Sp7) in the coordinated regulation of various mesenchymal cell types such as Chondrocyte, Osteoblast, Osteocyte, Odontoblast, and Adipocytes.

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Lamani Lab

Researcher using a pipette in the lab.

PI Name: Ejvis Lamani
SOD Research Theme: Craniofacial Development/Genetics
Research Focus: Dr. Lamani is a clinician scientist with advance training in Orthodontics specializing in craniofacial growth and development. Her interest lies on craniofacial biology and genetics with emphasis on dental development and related human genetic disorders. Her research aim is to translate the molecular biology and genetics of human growth and development to the treatment and future prevention of craniofacial and dental anomalies.

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Taichman Lab

Close up of gloved hands using a pipette in a lab.

PI Name: Russell S. Taichman, D.M.D., D.M.Sc.
SOD Research Theme: Oral Cancer/Bone Marrow Microenvironment
Research Focus: Our laboratory works at the intersection of how hematopoietic stem cells (HSCs), mesenchymal stem cells (MSCs) and disseminated tumor cells (DTCs) home, localize and engage the bone marrow microenvironment or niche for survival, function and protection from injury. We explore the paracrine, autocrine, intracrine and cell-matrix and adhesive interactions which regulate stem cell function. We have taken a broad systems approach to understanding the normal physiology of the marrow in terms of cytokine and hormonal regulation of stem cell function including the identification of unique stem cell properties of normal resident stem cells and DTCs.

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Zhang Lab

Dr. Ping Zhang posing for a photo in the lab.

PI Name: Ping Zhang
SOD Research Theme: Oral Microbiology, Infection/Host Response
Research Focus: The Zhang Lab focuses on studying the host-microbial interactions in the pathogenesis of oral infectious diseases, with a specific interest in understanding the signaling mechanisms involved in the regulation of inflammation and bone loss in the context of infection with periodontal pathogens.

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