Chalmers University in Gothenburg, Sweden

The collaboration between Chalmers University (Gothenburg, Sweden) and UAB’s Department of Biomedical Engineering is based on research funded by the European network for nanomedicine or EuroNanoMed. Professor Paul Gatenholm (Department of Chemical and Biological Engineering, Chalmers University) is leading and coordinating the program exploiting the use of bacterial-derived cellulose (BC) material to act as a tissue scaffold for human regenerative medicine applications. The bacterium Acetobacter xylinum has been shown to produce cellulose fibers hundreds of nanometers in diameter. Through careful control of the motion of the bacteria, it is possible to direct them to produce well-defined three-dimensional scaffolds for tissue reconstruction. The material is strong, elastic, and biocompatible but does not degrade over time. Currently in development are BC scaffolds for vascular graft replacement and human external ear replacement. The ear replacement (non load-bearing) represents the first step toward development of BC load bearing cartilaginous tissues. Joel L. Berry, Ph.D. (UAB Dept. of BME) will lead the design, development and testing of BC material for clinical application at UAB. Dr. Berry will serve as co-investigator to Prof. Gatenholm in BC-based tissue engineered ear auricle bioreactor development as well as development of specifications for a three-dimensional tissue printing on BC scaffolds.


Joel Berry, New Faculty in Biomedical Engineering,
collaborates with investigators at Chalmers University.