UAB - School of Medicine - Biochemistry and Molecular Genetics

A cancer drug may help treat human papillomavirus infections

Safe and effective therapeutic agents that can treat these cancer-causing viruses are greatly needed.

Attacking nonsense mutations in cystic fibrosis and a host of other diseases

For the 5-10 percent of cystic fibrosis patients with “nonsense” mutations, the trouble isn’t defective or misfolded proteins — it’s no protein at all.

Molecular virologists fight influenza at the molecular level

A study of how experimental inhibitors bind a key flu protein may guide novel antiviral compounds.

Six faculty awarded incentive grants to submit a second R01

Six School of Medicine faculty projects were recently funded through an AMC21 initiative giving NIH-funded investigators incentive to submit a second R01.

Biomedical workforce program proves successful in encouraging diversity, receives additional grant for support

UAB’s PREP Scholars proves successful by furthering student dreams as it receives a grant to continue preparing minority baccalaureate students for graduate programs.

Finding a key to unlock blocked differentiation in microRNA-deficient embryonic stem cells

Such basic research supports the goal of using stem cells in therapy, where an important hurdle is efficient differentiation.

Key factor identified in gene silencing

Understanding the mechanisms that turn sets of genes on or off is a fundamental quest in biology, and one that has clinical importance in diseases[…]

Key factor identified in gene silencing

This gene silencing by ubiquitinated histone is vital in normal embryo development, and it goes awry in some cancers.

Bedwell named chair of Biochemistry and Molecular Genetics

David M. Bedwell, Ph.D., has been named the chair of the Department of Biochemistry and Molecular Genetics. He has been leading the department as its[…]

One-step protein purification achieves high yields, purity and activity

This novel method improves purification of complex proteins by 10- to 500-fold, and it may aid both research and large-scale industrial production.

One-step protein purification achieves high yields, purity and activity

This novel method improves purification of complex proteins by 10- to 500-fold, and it may aid both research and large-scale industrial production.

A “Rosetta Stone” protein offers new mechanism of allostery

Allostery, a fundamental means of regulating enzymes, is crucial for living cells.

A “Rosetta Stone” protein offers new mechanism of allostery

Allostery, a fundamental means of regulating enzymes, is crucial for living cells.

Jia Cui wins graduate travel award from the American Society for Biochemistry and Molecular Biology

The award recognizes a significant paper by Cui in Cell Death and Differentiation.

Latest Headlines

A cancer drug may help treat human papillomavirus infections

Attacking nonsense mutations in cystic fibrosis and a host of other diseases

Molecular virologists fight influenza at the molecular level

Six faculty awarded incentive grants to submit a second R01

Biomedical workforce program proves successful in encouraging diversity, receives additional grant for support

Finding a key to unlock blocked differentiation in microRNA-deficient embryonic stem cells

Key factor identified in gene silencing

Key factor identified in gene silencing

Bedwell named chair of Biochemistry and Molecular Genetics

One-step protein purification achieves high yields, purity and activity

One-step protein purification achieves high yields, purity and activity

A “Rosetta Stone” protein offers new mechanism of allostery

A “Rosetta Stone” protein offers new mechanism of allostery

Jia Cui wins graduate travel award from the American Society for Biochemistry and Molecular Biology

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