Bevill. front.2013UAB is one of the seven inaugural NIH-designated Centers for AIDS Research established in 1988 and a world leader in HIV/AIDS research and patient care. UAB has been among the first to make the newest, most effective treatments available to patients, including the three-drug combination that today is the standard of care. From the field, a UAB-led team discovered the simian virus linked to all major HIV-1 variants and traced the exact route of HIV's spread to humans. U.S. News & World Report ranks the AIDS program No. 8 among "America's Best Graduate Schools," and the journal Science highlighted Birmingham and UAB's 1917 Clinic among 10 cities nationally excelling in efforts to combat the disease.
The role of the UAB CFAR is to expand the intersections of HIV research among multiple scientific disciplines and to catalyze groundbreaking research.  As a chartered University-wide Research Center, the CFAR provides focus and coordination for basic and clinical AIDS research activities to ensure an effective dialogue between administrators and investigators. To this end, the Center provides the necessary infrastructure in the form of core facilities, specialized equipment, administrative and technical support and advisory council to foster collaboration and research.  This approach is supported by the oversight of our Leadership and Executive Committees, Core Directors, Community Advisory Boards and External and Internal Advisory Committees. Translating our discoveries into AIDS prevention and awareness programs for the community are equally important missions of the CFAR.

History

The UAB Center for AIDS Research (CFAR), situated in the Medical Center complex of the University, is one of the seven original Centers, established in 1988 by the Centers for AIDS Research at the National Institute for Allergy and Infectious Diseases (NIAID), to stimulate research and scientific advancement concerning HIV/AIDS.
The Administrative Core (A) has served as the primary focal point for all HIV-related activities and efforts at UAB since the CFAR was initially funded in 1988. Dr. Eric Hunter was the founding Director of the Center and served from 1988 to 2004. Dr. Michael Saag took over in 2004 after having served as Co-Director from 1998 – 2004. Dr. Beatrice Hahn served as co-Director of the CFAR from 2004 - 2010. After Dr. Hahn's departure, In keeping with the tradition of Co-Directors, Dr. Michael Mugavero was appointed as Co-Director for Clinical Sciences in 2013. Dr. Jeanne Marrazzo was appointed as a Co-Director for Prevention Sciences in June 2017. In early 2018, Dr. Paul Goepfert assumed the role of Co-Director of Basic Sciences.

Leadership


Saag compressed  mugavero lrg    jeanne marrazzo  PGoepfert
Michael Saag, MD         Michael Mugavero, MD       Jeanne Marrazzo, MD          Paul Goepfert, MD 

The CFAR Leadership is composed of the Director, Co-Directors, Administrative Director, and the Financial Administrator. The Leadership Committee (LC) meets weekly to discuss management issues, day-to-day administration, emerging challenges, and opportunities. The Executive Committee (EC) is the main policy and decision-making committee of the Center and as such, it is responsible for the scientific and administrative management of the CFAR. The Leadership provides guidance to the Executive Committee and leads all meetings. The EC reviews and responds to scientific progress, logistical and technical issues, as well as the metrics of performance of the Cores and Core leaders. A critical function of the EC is a review of the Scientific Agenda, the performance of the IRGs, and the progress of the existing scientific programs.  See the Organization Tab for a depiction of our structure and members of these committees.

Mission


UAB CFAR mission:

To support UAB and Birmingham community-based investigators in the conduct of multidisciplinary, cutting-edge research in the prevention, pathogenesis, therapeutics, clinical care, and psychosocial manifestations of HIV and related disorders in the United States and around the world.

Organization


The CFAR is governed by advisory committees including the Leadership Committee, Executive Committee, External Advisory Committee, and Internal Advisory Board. The governance of the CFAR is led by the Leadership and Executive Committees under the direction of the Director (Michael S Saag, MD) and Co-Directors (Michael Mugavero, MD, Jeanne Marrazzo, MD and Paul Goepfert, MD). The organizational structure of the center is depicted below or click this pdflink for a larger version.
CFAR Organization.040518

Impact


The UAB CFAR is rooted in genuine multidisciplinary interactions and cross-campus collaborations, a hallmark of the Center since its inception. Institutional commitment, evidenced by strategic recruitment and provision of research space, resources, and annual funding from UAB Central Administration, coupled with the unique interdisciplinary environment at UAB, has allowed the HIV/AIDS research program to grow and develop continuously over the last 30 years, as evidenced by the scientific productivity over the years by the list of ‘firsts’by UAB investigators. 

The scientifically diverse membership base of UAB CFAR propels the rapid translation of fundamental and basic science knowledge of HIV/AIDS and its related disorders into clinical treatment, prevention programs, and effective community-based interventions. The UAB CFAR provides infrastructure, designated research space, five research core facilities with specialized equipment, and trained personnel, mentorship, and access to developmental research funds to over 185 active HIV investigators and the broader UAB research community. The success of the CFAR in advancing HIV/AIDS research at UAB is reflected in the growth of HIV-related extramural funding to $66M a year currently in spite of tightening AIDS funding priorities, and over 1,000 peer-reviewed HIV research publications over the last 5 years. 

Membership


Center membership is comprised of over 185 investigators from 33 different Departments (and 10 divisions within the Department of Medicine) and nine schools within the University. These investigators have secondary faculty appointments within the Center as they might in any other academic department. Those with interest from neighboring institutions or organizations are welcome to become "affiliate" members. The Center encourages investigators to participate in interdisciplinary research activities through Interdisciplinary Research Programs and workgroups. Investigators who are currently involved in HIV/AIDS research are invited to join the CFAR by becoming a member.  Anyone interested in HIV/AIDS and the impacts of this epidemic may join our email listserv.

Acknowledge the CFAR


Support the CFAR mission by acknowledging our services and programs in all grants, publications and abstracts by including: This research was supported by the University of Alabama at Birmingham (UAB) Center For AIDS Research CFAR, an NIH funded program (P30 AI027767) that was made possible by the following institutes: NIAIDNCINICHDNHLBINIDANIMH,NIA, NIDDK, NIGMS, FIC, NIDCR, and OAR.