2011 Neuroscience Poster Day

The poster day on Friday, February 18, 2011 was a great success.  Thank you to everyone who participated by presenting a talk or a poster or who attended the event to see what is going on in Neuroscience at UAB. 


Why do brain tumors cause seizures?
Harry Sontheimer. PhD
Professor, Deptment of Neurobiology
Director, Civitan International Research Center
Director, Center for Glial Biology in  Medicine

Epigenetic Mechanisms in Memory Formation
J. David Sweat, PhD
Evelyn F. McKnight Chair
Department of Neurobiology
Director, McKnight Brain Institute

Epigenetic mechanisms in the Entorhinal cortex regulate hippocampal area CA1 during consolidation of long-term memory
Swati Gupta
Graduate Student
Laboratory of Dr. Farah Lubin
Department of Neurobiology

HCN Channels Constrain Network Activity
Asher Albertson
MSTP Student
Laboratory of Dr. John Hablitz
Department of Neurobiology


Poster Title

Poster Authors

The Early-Onset Torsion Dystonia Gene Product, torsinA, is a Mediator of Intracellular Stress and Homeostasis

Pan Chen, John C. Ricketts, AJ Burdette, Laura A. Berkowitz, Kim A. Caldwell and Guy A. Caldwell

O-GlcNAcylation is a Dynamic Modulator of Synaptic Transmission at CA3-CA1 synapses
Erica W. Taylor, Lori L. McMahon  and John C. Chatham

Glia in Huntington's Disease: A Study in BACHD Mice

Toni Marie Mueller, William Lee, Reno C. Reyes, David Standaert, Michelle Gray

The UAB Intellectual and Developmental Disabilities Research Center Recombinant Technologies Core

Scott E. Phillips, Michael Brenner and Anne Theibert

Analysis and cloning of the epileptic mouse mutation, teetering.

Scott E. Phillips and Scott M. Wilson

Association of VSNL1 with schizophrenia, frontal cortical function, and biological significance for its gene product VILIP-1 as a modulator of cAMP levels and neuronal differentiation 

Braunewell K.H. Dwary A., Richter F., Schanrath K., Giegling. I., & D. Rujescu

Enhanced integration of newborn neurons after neonatal insults

Phyllis Pugh, Elena Adlaf, Chuan-Sheng Zhao, Sean Markwardt, Cristin Gavin, Jacques Wadiche, Linda Overstreet-Wadiche

Attenuation of EAE in a Transgenic Mouse with Astrocytic Expression of the RNA Regulator HuR

Crystal G. Wheeler, Burt Nabors, M.D. , Scott Barnum, Ph.D. , Xianzhen Hu , Trenton Schoeb, DVM, Ph.D., Peter H King, M.D.

Gestational Nicotine Exposure Yields Changes in Neurophysiology and Neurogenesis in the Dentate Gyrus

S. Hyman and R.A.J. Lester

The effect of speed of processing training on eye movements

Wesley Burge, Franklin Amthor, Rodolphe Nenert, Alexander Zotov, Kristina Visscher

Upregulation in the Expression of Tryptophan Hydroxylase 2 (TPH2) and Tyrosine Hydroxylase (TH) in the Lower Brainstem in Major Depression.

Kerman, I. A., Amilineni, N. S., Simpson, D. N., Jones, E. G., Bunney, W. E., Akil, H. , Watson, S. J.

Corpus Callosum Size in Chronic Stroke Patients and its Importance to Arm Motor Recovery

Chelsey Sterling. , Tyler Rickards, Ameen Barghi, Michael Graham, Ella Smith, Edward Taub, Ph.D., Victor Mark, M.D., Gittendra Uswatte, Ph. D. , Angela Chandler

The relationship of ongoing EEG activity to suppression of interfering visual input: a comparison between younger and older adults

Kristina Visscher, Neurobiology
Ryan Vaden, Neurobiology
Nathan Hutcheson, Neuroscience
Lesley Bryant, Neuroscience

Maximizing Spared Neural Resources in Chronic Stroke: Brain Parenchymal Fraction Correlates with Improvement due to Constraint-Induced Movement Therapy

Tyler Rickards, Chelsey Sterling, Michael Graham, Ameen Barghi, Victor W. Mark M.D., Edward Taub, Ph.D., Gitendra Uswatte, Ph.D.

Expanded Operational Classification of Early Neurological Deterioration (END)

Maruthi Kesani, MD, MS;  Clotilde Balucani, MD;  Kara Sands, MD;  Michael Lyerly, MD;  Kristian Barlinn, MD;  Limin Zhao, MD; Luis F. Cava, MD;  Ivan J. Lopez, MD;  Karen C. Albright, DO, MPH ; Anne W. Alexandrov, PhD;  Andrei V. Alexandrov, MD

Altered dendritic morphology of Purkinje cells in Dyt1 GAG knock-in and Purkinje-cell specific Dyt1 conditional knockout mice

Lin Zhang1, Fumiaki Yokoi1, Yuan-Hu Jin1, Mark P. DeAndrade1, Kenji Hashimoto2, David G. Standaert1 and Yuqing Li1*

Vacuolar ATPase: a Putative Therapeutic Target for Neurodegenerative Disease and Acute Neuronal Injury

John J. Shacka and the Shacka Lab

Impaired Activity-Dependent BDNF Release From Presynaptic Mossy Fibers and TrkB/TRPC Postsynaptic Signaling in CA3 Pyramidal Neurons of Mecp2 Mutant Mice

Wei Li and Lucas Pozzo-Miller

CLOTBUST-Hands Free Operator Independent Ultrasound Device: Initial Safety
 Testing in Healthy Volunteers

Kristian Barlinn, MD; Andrew D. Barreto, MD; David S. Liebeskind MD; April Sisson, RN; Limin Zhao, MD;  Luis Cava, MD; John F. Rothrock, MD; Mark E. Schafer, PhD; John Alleman, BS, MBA; James C. Grotta, MD; Andrei V. Alexandrov, MD

Estimated Peak Rarefaction Pressure Predicts Recanalization and Outcome in the
Transcranial Ultrasound in Clinical SONothrombolysis (TUCSON) Trial 

Kristian Barlinn, MD; Georgios Tsivgoulis, MD; Carlos A. Molina, MD; Dmitri A. Alexandrov, BSEM;
Mark E. Schafer, PhD; John Alleman, BS, MBA; Andrei V. Alexandrov, MD; for the TUCSON Investigators.

Mouse model of bvFTD specifically targets the salience network

Dheepa Sekar

The Natural Ecology of Primate Visual Cortical Neurons

Timothy J. Gawne, Jack R. Wimbish, William Kraft

Tau and potassium channel Kv4.2 in Alzheimer disease-related neuronal dysfunction

Alicia Hall, Katie Pullom and Erik Roberson

An fMRI investigation of delay discounting in schizophrenia 

Kathy B. Avsar, David White, Meredith Reid, Mark Bolding, Luke E. Stoecke, James E. Cox1, Rosalyn E. Weller, Adrienne C. Lahti

Post Graduate Academic Neurovascular Fellowship for Advanced Practice Nurses
and Physician Assistants Significantly Increases tPA Treatment Rates: Results from the First Graduating Class of  the NET SMART Program

Anne W. Alexandrov, PhD, FAAN, Tenisha Baca, MEd, Karen Albright, DO, MPH, Stephen DiBiase, Andrei V. Alexandrov, MD, for the NET SMART Faculty and Fellows

HCN channels and 4-AP induced epileptiform activity

Steven Palladino, Dr. John Hablitz

Bradykinin promotes the chemo-tactic invasion of primary brain tumors

Vedrana Montana and Harald Sontheimer

Can Clinical Presentation Provide Clues to Conversion Disorder in Code Stroke Patients?  A Descriptive Analysis of Clinical Findings

Mary Brethour, PhD(c), CRNP; Karen C. Albright, DO, MPH; Anne W. Alexandrov, PhD, RN, CCRN, FAAN

Ventral Striatum Neurodegeneration is Linked to Behavioral Symptoms in Frontotemporal Dementia

Brian A. Warmus, Dheepa R. Sekar, and Erik D. Roberson

The Value of CT Perfusion (CTP) Prognostic Maps in Predicting Reversible and Irreversible Neurological Dysfunction Following Reperfusion Therapies

Limin Zhao, MD; Kristian Barlinn,MD; Karen C. Albright, MD; Maruthi Kesani, MD; Kara Sands, MD;Michael Lyerly, MD; Luis Cava, MD; Clotilde Balucani, MD; Anne W. Alexandrov, PhD; Mark Harrigan, MD; Joseph A. Horton,MD2; Damon E. Patterson, MD; Andrei V. Alexandrov, MD

The regulator of active DNA demethylation, Gadd45b, suppresses memory consolidation

Faraz A. Sultan, Jennifer Tront, Dan A. Liebermann, J. David Sweatt

Lithium ameliorates behavioral and physiological phenotypes of fragile X syndrome in Fmr1 knockout mice


HCN Channels Constrain Network Activity

Asher J. Albertson, Sydney B. Williams, Dr. John Hablitz

Immunocytochemical Localization of Enkephalin in the Human Striatum: A Postmortem Ultrastructural Study

Lesley A. Bryant, Joy K. Roche, Rosalinda C. Roberts

Glycogen synthase kinase-3 inhibitors provide a mechanism to control neuroinflammation. 



Vladimir Grubišić, Randy Stout, Robert Grammer, Vladimir Parpura

Intracellular Signaling in Schizophrenia

A.Funk, R.McCullumsmith, V.Haroutunian, J.Meador-Woodruff

NR2B-Chromatin Structure Regulation in the Kainate-model of epilepsy 

R. Ryley Parrish, Farah D. Lubin

Modulatory effect of trait anxiety on the unconditioned response during fear conditioning

Kimberly H. Wood, Lawrence W. Ver Hoef, and David C. Knight

Astrocytic calcium dynamics and exocytosis, and their role in synaptic neurotransmission and animal behavior.

Reno C. Reyes, William Lee, Vladimir Grubisic, Randy F. Stout, Wei Liu, Erik B. Malarkey and Vladimir Parpura

TARP γ and cornichon dysregulation in the ACC and DLPFC in schizophrenia

J. Drummond, J. Tucholski, D. Dahl, M. Simmons, V. Haroutunian, and J. H. Meador-Woodruff

A Neuroprotective Role of Angiogenin in Models of Parkinson Disease

Trent Steidinger, David Standaert, Talene Yacoubian

Transduction of Dopamine Neurons by Adenoviral Vectors is Modulated by CAR Expression: Rationale for Tropism Modified Vectors in PD Gene Therapy

Travis B Lewis, Joel N Glasgow, Anya M Glandon, David T Curiel, and David G Standaert.

Targeting the Tau-Fyn Interaction in Alzheimer’s Disease

Nick Cochran and Erik Roberson

Mitochondrial Ca2+ update capacity as a therapeutictarget in Huntington's disease

Ashish Kumar, Giselle M. Perry, Sara Tallaksen-Greene,Mary Y. Heng,
Andrew Kneynsberg, Thomas van Groen, Peter J. Detloff, Roger L. Albin
and Mathieu Lesort

Inflammatory modulation of NMDA receptors on oligodendrocytes 

Brandi J. Baker, Igor Gembitsky, and Tara M. DeSilva

Histone Methylation: a critical regulator of long-term memory formation

Swati Gupta, Robin L. Davis, Farah D. Lubin

Extraction of stimulus parameters from responses of directionally selective retinal ganglion cells

Przemyslaw Nowak, Timothy J. Gawne, Allan C. Dobbins, Franklin R. Amthor

Directed analysis of candidate genes implicated in autism 

Rebecca L. Tomlinson, Dan E. Arking and Andrew B. West

The length of estrogen deprivation, not chronological age, limits the ability of estrogen replacement to enhance synaptic function in hippocampus of ovariectomized female rats.

Lindsey C. Vedder, Caroline C. Smith, Amy R. Nelson, Teruko M. Bredemann, Lori L. McMahon             

Insulin Deficiency Promotes Alzheimer’s Disease

A. Kneynsberg, A. Kumar, G. Perry, I. Kadisha, T. van Groen, R. Jope, E. Roberson, and M. Lesort

Loss of association between PGC-1alpha and its putative targets in the dorsolateral prefrontal cortex of patients with schizophrenia  

Rita M. Cowell, J. Matt Rutherford, Elizabeth K. Lucas, Vahram Haroutunian, James H. Meador-Woodruff

Region-Specific Transcriptional Changes of Interneuron Markers in the R6/2 model of Huntington Disease

Dougherty SE, Lesort M, Cowell RM

Novel targets of the transcriptional coactivator PGC-1α in the brain: Implications for neurological disorders

Elizabeth K. Lucas, Courtney A. Sparkman, Alisa T. Trinh, & Rita M. Cowell

Impaired presynaptic structure and function in area CA1 of symptomatic Mecp2 mutant mice do not account for hippocampal hyperexcitability

Gaston Calfa, Michelle D. Amaral, John Hablitz and Lucas Pozzo-Miller

CaMKII regulation of chloride channels in human glioma cell proliferation

Vishnu Cuddapah and Harald Sontheimer

Sympathetic sprouting rescues cholinergic innervation and compensates for deficits in
M1 receptor function, non-amyloidogenic processing of APP, and learning.

Amy R. Nelson, Krystyna Kolasa, Caroline C. Smith, and Lori L. McMahon

Glutamatergic signaling during cerebral white matter development

Heather Minkel, Brandi Baker, Igor Gembitsky, and Tara DeSilva

Regulation of endoplasmic reticulum stress-induced neuron death

Arindam Ghosh, Barbara.J.Klocke and Kevin.A.Roth

The role of the temporoparietal junction in mindreading and its dysfunction in autism

Rajesh K. Kana, Ph.D., Lauren L. Libero, Hrishikesh Deshpande

Voltage-gated Calcium Channels of C. elegans Glial Cells

Randy F. Stout Jr., Vladimir Parpura. 

Frontotemporal Dementia-related Behavioral Abnormalities in a Murine Model of Progranulin Insufficiency


Using LCM-qPCR to Study Neuronal Circuitry of Schizophrenia in Postmortem Human Brain Tissue

Micah Simmons, Stefani Yates, Grant Nelson, Vahram Haroutunian, Robert McCullumsmith and James H. Meador-Woodruff

Environmental enrichment enhances synaptic input to newborn neurons during their critical period

Jessica Chancey, Matthew Sapp, Phyllis Pugh, Elena Adlaf, Jacques Wadiche, Linda Overstreet-Wadiche

Fcγ Receptors are Required for NF-κB Signaling, Microglial Activation and Dopaminergic Neurodegeneration in an AAV-synuclein Mouse Model of Parkinson’s Disease

Shuwen Cao, Shaji Theodore and David G. Standaert

Developmental underpinnings of individual differences in rodent novelty-seeking and emotional reactivity

Sarah M. Clinton, John D. H. Stead, Sue Miller, Stanley J. Watson, and Huda Akil

Virtual Interactive Presence Technology

Barton L. Guthrie, M.D., Alan M. Shih, Ph.D., Marcus W. Dillavou, P. Corey Shum

Altered dendritic morphology of Purkinje cells in Dyt1 GAG knock-in and Purkinje-cell specific Dyt1 conditional knockout mice 

Lin Zhang, Fumiaki Yokoi, Yuanhu jin, Mark P. DeAndrade, David G. Standaert, and Yuqing Li

Elevated Garp2 Mice Exhibit Decreased Light Response and Increased Phototransduction Gain

Steven J. Pittler,  Glen R. Rubin, Timothy W. Kraft, and  Shanta Sarfare

The Center for Glial Biology in Medicine is pleased to announce the upcoming Bevill Conference on Glial Biology in Medicine scheduled for December 5-7, 2010.  The preliminary conference program and registration page can be found at www.glia.uab.edu.  Through the generous support of the Bevill Family and the UAB Comprehensive Neuroscience Center registration fees for the 2010 conference are being waived.  We hope that you will encourage your students and postdocs to attend this upcoming meeting.  Please contact Anne Wailes (awailes@uab.edu) with any questions concerning the conference. 

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