Examples of cystic fibrosis seminar presentations over the past several years include the following:
Gergely Lukacs, M.D., Ph.D., McGill University, Montreal
"Folding and misfolding of CFTR: A cellular perspective"
Benjamin M. Gaston, M.D., University of Virginia Health Sciences Center
"S-Nitrosothiol Metabolism in asthma and CF"
Laura Silo-Suh, Ph.D. and Sang-Jin Suh, Ph.D., Auburn University, Department of Biological Sciences
"Changing faces of Pseudomonas aeruginosa: From environment to the Cystic Fibrosis lung"
Joseph Zabner, M.D., Department of Internal Medicine, University of Iowa
"The adenovirus receptor and adenovirus"
Terry Machen, Ph.D., Department of Molecular and Cell Biology, University of California, Berkeley
"Innate immune response in airway epithelia to P. aeruginosa: Role for CFTR?"
Ron Rubenstein, M.D., Ph.D., University of Pennsylvania School of Medicine
"More ramblings about CFTR and ENaC trafficking"
Marisa Sousa, Center of Human Genetics, National Institute of Health Dr Ricardo Jorge (Lisbon, Portugal)
"Mechanism of action in heterologous systems and native tissue efficacy of small molecules on mutant CFTR"
Sam Moskowitz, M.D., Massachusetts General Hospital
"Polymyxin resistance in cystic fibrosis: A tale of two (or more) Pseudomonas aeruginosa regulatory systems"
Karl Kunzelmann, M.D., University of Regensburg, Germany
"AMPK and CK2--Two Kinases that Regulate ENaC"
Robert Tarran, Ph.D., University of North Carolina Chapel Hill
"Estrogen and Cystic Fibrosis lung disease"
Timor Baasov, Ph.D., The Technion, Israel
"To teach old drugs new tricks: Redesign of aminoglycosides for treatment of human genetic diseases"
Christine E. Bear, Ph.D., The Hospital for Sick Children, Canada
"Small molecule modulators provide a tool for probing the molecular phenotype of mutant CFTR"
Kasper Aanaes, M.D., University of Copenhagen
"The paranasal sinuses: A focus for bacterial lung infections in Cystic Fibrosis"
Mitchell Drumm, Ph.D., Case Western Reserve University
"GWAS for CF modifiers"
Michael J. Welsh, M.D., Howard Hughes Medical Institute, University of Iowa
"Insights into Cystic Fibrosis from a new model"
Elizabeth Miller, Ph.D., Columbia University
"Packaging proteins with precision: How cells enforce quality control in the secretory pathway"
Robert C. Ford, Ph.D., The University of Manchester, UK
"Structural analysis of ATP-binding cassette transporters using electron- and X-ray crystallography"
David C. Dawson, Ph.D., Oregon Health & Science University
"CFTR: Using computational and experimental techniques to identify a binding site for the pore-blocker,
Stuart W. Peltz, Ph.D., President and Chief Executive Officer, PTC Therapeutics, Inc.
"Post-transcriptional control pathways as targets for therapeutic intervention"
James Kiley, Ph.D., Director of the Division of Lung Diseases, NHLBI
"Future directions in lung research"
Assem Ziady, Ph.D., Pediatrics, Emory University
"Nrf2 dysregulation in CF airway epithelial cells"
Chris Mueller, Ph.D., Pediatrics, University of Massachusetts
"CFTR dysfunction and its immune consequences"
Fred Van Goor, Ph.D., Cystic Fibrosis Research Program, Vertex Pharmaceuticals
"Discovery and development of CFTR modulators for the treatment of Cystic Fibrosis"
John F. Engelhardt, Ph.D., Anatomy & Cell Biology, University of Iowa
"Modeling cystic fibrosis lung disease and diabetes in the ferret"
Phil Farrell, M.D./Ph.D., Pediatrics and Population Health Sciences, University of Wisconsin
"CFTR2 and newborn screening"
David Stoltz, M.D./Ph.D., Pulmonary & Critical Care Medicine, University of Iowa
"The early pathogenesis of CF: Insights gained from Homo Sapiens and Sus Scrofa"
"Intestinal organoids: New tools in studies of cystic fibrosis and diarrheal disease"
John F. Engelhardt, Ph.D. Devpartment Chair, Anatomy & Cell Biology, University of Iowa
"Modeling Cystic Fibrosis Lung Disease and Diabetes in the Ferret"
Hitendra S. Chand, Ph.D., Associate Staff Scientist, Lovelace Respiratory Research Institute & Asst. Professsor, Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine
"Role of Hyperplastic Epithelial Cells in Chronic Airway Diseases"