Ling Li, PhD, DVM

Associate Professor
Dept. of Medicine
Div. of Gerontology, Geriatrics, and Palliative Care           

Contact Information:

Office Address: BDB 630
Phone: 934-1889
Websites: School of Medicine Faculty Profile


Yangzhou University, China
BS/DVM, Veterinary Medicine, 1982

Yangzhou University, China 
MS, Experimental Medicine, 1986

Iowa State University, Ames, IA 
PhD, Molecular, Cellular, and Developmental Biology, 1995

Post-Graduate Training:

Rockefeller University/Mt. Sinai Medical Center, New York, NY 
Postdoctoral Fellow, Lipoprotein Metabolism and Atherosclerosis, 1995-6

University of Alabama at Birmingham 
Postdoctoral Fellow, Neurobiology of Alzheimer’s disease, 1997-9

Research Interests:

Connections Between Atherosclerosis, Diabetes, and Alzheimer's Disease

Research Description:

Our research program is focused on the genetic and pathophysiological connections between atherosclerosis, diabetes, and Alzheimer’s disease (AD) using transgenic/knockout mouse models. We employ a combination of molecular, cellular, electrophysiological, and behavioral approaches in our research. Current research activities in our laboratory include: 1) Investigation on the role of dietary and/or genetically induced hypercholesterolemia in the development of AD-like neuropathology and behavior in transgenic mouse models of AD; 2) Potential application of cholesterol-lowering drugs such as statins in the prevention and treatment of AD and other age-related dementia; 3) Investigation on the role of sugar-induced obesity and insulin resistance in the development of AD; 4) Investigation on the role of amyloid-beta peptide in atherogenesis; and 5) Studies on structure and function of apolipoprotein A-I, a major protein component of the cardio-protective high-density lipoproteins.


DRC Membership Category:

Senior Scientist