Genetics and Genomics Seminar
12:00 p.m.
Finley Conference Center
Friday, December 13 | “Targeting α2AAR: Solution for Alzheimer’s Disease” | Qin Wang, Ph.D., Professor, Department of Cell, Developmental and Integrative Biology, UAB
Target Audience: UAB Broader Genetics Community
There is no commercial support for this session
Objectives:
1. Review general features of Alzheimer’s disease
2. Understand noradrenergic dysfunction in Alzheimer’s disease
3. Recognize novel roles of norepinephrine in promoting Alzheimer’s disease pathogenesis
4. Identify α2A adrenergic receptor as a therapeutic target for Alzheimer’s disease
Sponsored for CME credit by UAB Division of CME
The University of Alabama School of Medicine is accredited by the Accreditation Council of Continuing Medical Education (ACGME) to provide continuing medical education for physicians.
The University of Alabama School of Medicine designates this Regularly Scheduled series for a maximum of 1 AMA PRA Category 1 Credit. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Archive
Friday, December 6 | “Bioactive Retinoic Acid: Gene knockouts reveal unexpected roles” | Natalia Y. Kedishvili, Ph.D., Professor, Department of Biochemistry and Molecular Genetics, UAB
Friday, November 22 | “Selective RANK Signaling Pathways as Novel Drug Targets for Breast Cancer Prevention” | Xu Feng, Ph.D., Professor, Department of Pathology
Friday, November 15 |“Population Genetics in an era of Precision Medicine” | Eimear Kenny, Ph.D., Director, Center for Genomic Health, Associate Professor of Medicine, Associate Professor of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai
Friday, November 8 | “The identification and targeting of novel oncogenic ncRNA in human cancer” | Mick Edmonds, Ph.D., Assistant Professor, Genetics Research Division, Department of Genetics, UAB
Friday, November 1 | "Computational Drug Repositioning Strategies for Precision Medicine 2.0" | Jake Chen, Ph.D., Chief Bioinformatics Office, Professor, Department of Genetics, Informatics Institute, UAB
Friday, October 25 | “Mathematical modeling: Aiding biomedical discoveries" | Andre Leier, Ph.D., Assistant Professor, Department of Genetics, Assistant Professor, Department of Cell, Developmental and Integrative Biology, Associate Scientist, O’Neal Comprehensive Cancer Center, Member, Gregory Fleming James Cystic Fibrosis Research Center
Friday, October 18 | “Clinical Application of Genome Sequencing: The Children’s of Alabama Experience” | Anna C.E. Hurst, M.D., MS, FACMG, Assistant Professor,Department of Genetics,UAB
Friday, September 27 | “Fluid-Mosaic Membrane in Aging, Disease and Mitochondrial Function and The use of Membrane Lipid Replacement to Reduce Fatigue, Pain and Other symptoms while Improving Mitochondrial Function” | Garth Nicolson, Ph.D., M.D., Professor Emeritus, President and Founder, The Institute for Molecular Medicine, Huntington Beach, CA
Friday, September 13 | “From Genetic to Pharmacological Inhibition of TXNIP- Effects on Diabetes” | Anath Shalev, M.D., Professor of Medicine - Endocrinology, Diabetes & Metabolism, Nancy R. and Eugene C. Gwaltney Family Endowed Chair in Juvenile Diabetes Research, Director, UAB Comprehensive Diabetes Center
Friday, September 6 | “Genetic and epigenetic regulation of Duchenne muscular dystrophy” | Matthew S. Alexander, Ph.D., Assistant Professor, UAB Pediatric Neurology
Friday, May 17 | “Implementation of a Personalized Medicine Program Across a Community Health System” | Peter J. Hulick, M.D., MMSc, FACMG, Medical Director, Mark R. Neaman Center for Personalized Medicine Division, Head, Center for Medical Genetics NorthShore University HealthSystem, Clinical Assistant Professor, University of Chicago, Pritzker School of Medicine
Friday, May 10 | “STAT3: From Fundamental Discoveries to Novel Targeting Platforms” | Hua Yu, Ph.D., Billy and Audrey L. Wilder Professor in Tumor Immunotherapy, Associate Chair and Professor, Department of Immuno-Oncology, Co-leader, Cancer Immunotherapeutics Program, City of Hope Comprehensive Cancer Center
Friday, May 3 | “InterGenomic Cross Talk Underlying Aging and Cancer” | Keshav K. Singh, Ph.D., Joy and Bill Harbert Endowed Chair in Cancer Genetics and professor, Department of Genetics University of Alabama at Birmingham
Friday, April 19 | “Enhancing Precision Oncology at UAB” | Eddy S. Yang, M.D., Ph.D., Professor, Vice Chair for Translational Science, Department of Radiation Oncology, University of Alabama at Birmingham
Friday, April 12 | “Genetics and Epigenetic Regulation of Heart Development in Mice” | Kai Jiao, M.D., Ph.D., Associate Professor, Department of Genetics, Genetics Research Division, University of Alabama at Birmingham
Friday, March 22 | “The Impact of Geometry, Diffusion Barriers and Stochasticity in Cell Polarity and Protein Dynamics” | Tatiana Marquez-Lago, Ph.D., Associate Professor, Department of Genetics, Research Division, University of Alabama at Birmingham
Friday, March 15 | “Functional characterization of human disease-associated gene variants using the vertebrate animal model Xenopus laevis” | Chenbei Chang, Ph.D., Professor, Department of Cell, Developmental and Integrative Biology, UAB
Friday, March 8 | “RAS and the Plasma Membrane: A Complicated Relationship” | John Hancock, MA MB BChir PhD ScD MRCP FRACP, Professor and Chairman, Department of Integrative Biology and Pharmacology, Executive Director, The Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center
Friday, February 22 | “Epithelial Homeostasis in Development and Disease” | Ian G. Macara, PhD, Professor and Louise B. McGavock Chair, Department of Cell and Development Biology, Vanderbilt University Medical Center
Friday, February 15 | “Structural Variations of the Immunoglobulin Receptors and
Clinical Phenotype” | Robert P. Kimberly, M.D., Director, Center for Clinical and Translational Science University of Alabama at Birmingham
Friday, February 1 | “A Novel Technology Developed at UAB for Phenomic Research and Drug Discovery” | John L. Hartman IV, M.D., Associate Professor, UAB Department of Genetics
Friday, January 18 | "Polycystic Kidney Disease-Treatment Options Update" | Michal Mrug, M.D., Professor of Medicine, Department of Nephrology
Friday, January 11 | “The algorithm for precision medicine” | Matthew Might, Ph.D., Professor of Computer Science, Director, UAB’s Hugh Kaul Precision Medicine institute, University of Alabama at Birmingham
Friday, December 14 | “Molecular profiling in ovarian cancer” | Rebecca C. Arend, M.D., Assistant Professor, Department of Obstetrics and Gynecology, University of Alabama at Birmingham
Friday, December 7 | “Epithelial-mesenchymal Transition in Breast Cancer Progression and Metastasis” | Binhua (Peter) Zhou, M.D., Ph.D., Co-Director, Center of Biomedical Research Excellence in Cancer and Metabolism, University of Kentucky, Lexington, KY
Friday, November 30 | "A Mitochondrial Etiology of Common 'Complex' Diseases" | Douglass C. Wallace, Ph.D., Professor, Department of Pathology and Laboratory Medicine, University of Pennsylvania
Monday, November 19 | "Design and evolution of trans-splicing group I intron ribozymes" | Ulrich F. Muller, Ph.D., Associate Professor, Department of Chemistry and Biochemistry, University of California at San Diego
Friday, November 2 | “Unraveling the complex roles of SIN3 in breast cancer metastasis”| Douglas R. Hurst, Ph.D., Assistant Professor, Department of Pathology, University of Alabama at Birmingham
Friday, October 19 | "Patient-Specific NF1 Rodent Models & Gene Correction Therapies" | Robert A. Kesterson, Ph.D., Professor, Department of Genetics, UAB
Friday, October 12 | "The ELMOD family of ARF family GAPs: roles in mitochondria, cell cycle, ciliogenesis, and transcriptional regulation" | Richard A. Kahn, Ph.D., Professor, Department of Biochemistry, Emory University
March 9, 2018 | Phillip Owens, Ph.D. | University of Colorado
March 16, 2018 | Richard Finnell, Ph.D. | Baylor College of Medicine
March 23, 2018 | Anthony Wynshaw-Boris, M.D., Ph.D. | Case Univeristy
April 4, 2018 | Nita Limdi, PharmD, Ph.D. | UAB
April 13, 2018 | Chulan Kwon, MS, Ph.D. | John Hopkins University
April 20, 2018 | Merry-Lynn McDonald, Ph.D. | University of Alabama at Birmingham
May 4, 2018 | Mikhail Alexeyev, Ph.D., I University of South Alabama
May 11, 2018 | Jiangbing Zhou, Ph.D. I Yale University
Date |
Speaker |
Institution |
Title |
| 9/2/2016 | Margaret R. "Peggy" Wallace | Indiana University | Molecular and Cellular Studies of Neurofibromatosis 1 |
| 9/9/2016 | |||
| 9/16/2016 | Vidu Garg, MD | Nationwide Children's Hospital | Insights into the genetics of congenital heart disease: From human genetics to mouse models |
| 9/23/2016 | STATE DEPT MEETING | ||
| 9/30/2016 | |||
| 10/7/2016 | Jake Chen | Journal Club | |
| 10/14/2016 | IMMERSON COURSE | ||
| 10/21/2016 | |||
| 10/26/2016 | |||
| 11/4/2016 | Gabrielle Geddes, M.D. | Medical College of Wisconsin/ Children's Hospital of Wisconsin | Ciliopathies and Congenital Heart Disease |
| 11/11/2016 | Patty Sanderson | Journal Club | |
| 11/18/2016 | SCIENTIFIC RETREAT | ||
| 11/25/2016 | |||
| 12/2/2016 | Brian Spurlock | Journal Club | Mechanisms of Autophagy as discovered by Dr. Yoshinori Oshumi Nobel Prize in Physiology or Medicine, 2016 |
| 12/9/2016 | Sophie Astrof, PhD | Thomas Jefferson University | Cell type-specific function of fibronectin in cardiovascular development |
| 12/16/2016 | |||
| 12/30/2016 | |||
| 1/6/2017 |
Li, Yi, PHD *This lecture will take place from 2 - 3 p.m. in the Finely Conference Room |
Baylor College of Medicine` | Unexpected players in cancer metastasis |
| 1/13/2017 | Joy Dean | Journal Club | |
| 1/20/2017 | |||
| 1/27/2017 | |||
| 2/3/2017 | Benjamin Tu, PhD | UT-Southwestern University | A metabolic vulnerability of tumors revealed by yeast |
| 2/10/2017 | |||
| 2/17/2017 | Jariya Upadiya | Journal Club | Fox transcription factors in cardiovascular development |
| 2/24/2017 | Barbara K Burton MD | Ann & Robert H. Lurie Children’s Hospital of Chicago | Lysosomal Acid Lipase Deficiency |
| 3/3/2017 | RARE DISEASE SYMPOSIUM | ||
| 3/10/2017 | Dr. Kume Tsutomu | Northwestern University | Fox transcription factors in cardiovascular development |
| 3/17/2017 | Bruce Walcheck | University of Minnesota | Regulating Receptor Levels on Leukocytes to Improve Their Function During Disease |
| 3/24/2017 | Stephen Dalton | University of Georgia | “MYC coordinates metabolic control with pluripotent stem cell fate decisions” |
| 3/31/2017 | |||
| 4/7/2017 | Dr. David Gutmann | Washington Univ Neurofibromatosis Center | Neurofibromatosis: New Insights from an Old Gene |
| 4/14/2017 | Danny Welch, PhD | Univ of Kansas Medical Center | The forgotten genome: Surprising roles of mitochondria in cancer metastasis. |
| 4/21/2017 | Genetics Graduation - Robert Marion | Albert Einstein College of Medicine | |
| 4/28/2017 | Deborah Yelon | Univ of California San Diego | “Molecular Mechanisms Regulating Cardiac Architecture in Zebrafish” |
| 5/5/2017 | Dr. Prabhat Goswami | A redox cycle within the cell cycle: ring in the old with the new. | |
| 5/12/2017 | Deeann Wallis, PhD | Journal Club | |
| 5/19/2017 | IMMERSION COURSE | ||
| 5/26/2017 | Shizen (Emily) Wang, Ph.D | Seminar Series | “Cancer-derived extracellular miRNA in breast cancer metastasis”. |
| 6/9/2017 | Dr. Melissa Harris | Uncovering gene regulatory networks for somatic stem cell self-renewal. | |
| 9/29/2017 | Dr. Elizabeth Worthey | John Hartman | Preparing for the Precision Medicine Revolution: Transforming Whole Genome Sequencing Data into Clinically Actionable Knowledge |
| Date | Speaker | Institution | Title |
| 09/04/2015 | |||
| 09/11/2015 | |||
| 09/18/2015 | State Department Meeting | ||
| 09/25/2015 | |||
| 10/02/2015 | |||
| 10/09/2015 | |||
| 10/16/2015 | Journal Club- Justin Avery |
UAB | |
| 10/23/2015 | Dr. Sunjung Kim | Children's National Medical Center | "The Role of Tumor Suppressor genes in Central Nervous System (CNS) Disorder |
| 10/30/2015 | Deeann Wallis, Ph.D | Texas A&M University | "High-Throughput Differentiation and Screening of a Library of Mutant Stem Cell Clones Defines New Host-Based Genes Involved in Infection' |
| 11/06/2015 | Journal Club- Ved Prakash Mooga |
UAB | |
| 11/13/2015 | Areeg El-gharbawy | University of Pitsburg | |
| 11/20/2015 | |||
| 11/27/2015 | Thanksgiving holiday | ||
| 12/04/2015 | Journal Club- Akila Subramanium |
UAB | |
| 12/11/2015 | Joy Lincoln , Ph.D |
Nationwide Children's Hospital Research Institute | |
| 12/18/2015 | Stanley Lei Qi, PhD | Stanford University | |
| 12/25/2015 | Holiday | ||
| 01/01/2016 | Holiday | ||
| 01/08/2016 | |||
| 01/15/2016 | Day before MLK Weekend | ||
| 01/22/2016 | Journal Club - Kasturi Mitra, Ph.D |
UAB | |
| 01/29/2016 | Ivan Moskowitz, MD, PhD | University of Chicago | "Gene Regulatory Networks in Cardiac Development and Homeostasis" |
| 02/05/2016 | Mick Edmonds, PhD, MS | Vanderbilt University Medical Cente | |
| 02/12/2016 | Cancelled- Rescheduled for March 4. | ||
| 02/19/2016 | Toren Finkel | NIH | "Mitochondria and Aging" |
| 02/26/2016 | Joy Lincoln , Ph.D | Nationwide Children's Hospital Research Institute | "Exploring heart valve endothelial cell dynamics" |
| 03/04/2016 | Journal Club- Ashley Turner |
UAB | |
| 03/11/2016 | Stanley Lei Qi, PhD | Stanford University | "CRISPR/Cas9 for complex genome regulation and disease modeling" |
| 03/18/2016 | Journal Club- Austin Hamm |
UAB | |
| 03/25/2016 | Spring Break | ||
| 04/01/2016 | Spring Break | ||
| 04/08/2016 | Vishal Gohil | Texas A & M University | "Discovering novel mitochondrial disease genes by integrative genomics" |
| 04/15/2016 | Journal Club- Sean Santos |
UAB | |
| 04/20/2016 | Woojin An, Ph.D., | University of Southern California | “Chromatin dynamics and gene regulation” |
| 04/22/2016 | Todd Lowe, Ph.D. | University of California Santa Cruz | Unraveling the Complex Roles for 500+ Human tRNA Genes and their Ubiquitous Small RNA Fragments |
| 04/29/2016 | Maria Alejandra San Martin, PhD | Emory University | “Diverse roles of NADPH oxidases in the VSMC phenotype” |
| 05/06/2016 | Anil Shanker, PhD | Meharry Medical College School of Medicine | "Preventing Immune Escape Variants of Cancer" |
| 05/13/2016 | |||
| 05/20/2016 | Brian Kennedy, PH.D. / LRC-235 | Buck Institute for Aging | “The Age of Aging – Can We Intervene?” |
| 05/27/2016 | Jing Yang PhD | University of California, San Diego | "Epithelial-Mesenchymal Plasticity in Carcinoma Metastasis" |
| 06/17/2016 | Journal Club- Anna Hurst |
UAB |
| Date | Speaker | Institution | Title |
| 09/12/2014 | Bruce Korf, M.D., Ph.D. | Professor and Chair, Department of Genetics, UAB | State of the Department Address |
| 09/19/2014 | No Seminar | ||
| 09/26/2014 | Rebecca Dodd, Ph.D. | Senior Research Associate, Duke University Medical Center | "New Mice for Old Questions: Modeling Soft-tissue Sarcoma" |
| 10/03/2014 | No Seminar | ||
| 10/10/2014 | Todd Nystul, Ph.D. | Assistant Professor, University of California San Francisco | "To Be (Stem) or Not to Be: Polarity and pH Define Cell Fate in an Epithelial Stem Lineage" |
| 10/17/2014 | Becky Nagy, MD, LGC | Assistant Professor, The Ohio State University | "The Use of Next Generation Sequencing in Novel Gene Discovery: A Tale of Two Cities" |
| 10/24/2014 | Journal Club- Trevor Carden | UAB | |
| 10/31/2014 | Sean Wu, MD, Ph.D | Professor, Stanford University | "Molecular Regulation of Cardiac Development: Implications in Regenerative Therapy" |
| 11/07/2014 | Hudson Alpha Retreat- NO SEMINAR | N/A | N/A |
| 11/14/2014 | Journal Club-Anil Challa | UAB | |
| 11/21/2014 | Anil Challa, Ph.D | Instructor, University of Alabama at Birmingham | |
| 11/28/2014 | Thanksgiving Holiday | N/A | N/A |
| 12/05/2014 | Hyeong-Reh Choi Kim, Ph.D. | Assistant Professor, Wayne State University | "A Novel Function of PDGF D in Prostate Cancer Bone Metastasis: New Biology of an Old Growth Factor Family Member" |
| 12/12/2014 | No Seminar | ||
| 12/19/2014 | Journal Club- Warren L Simmons | UAB | |
| 12/26/2014 | Christmas Holiday | N/A | N/A |
| 01/02/2015 | New Years Holiday | N/A | N/A |
| 01/09/2015 | Mark Gillespie, Ph.D. | Professor and Chairman Dept. of Pharmacology, University of South Alabama | |
| 01/16/2015 | MLK Holiday | N/A | N/A |
| 01/23/2015 | William Pu, MD. | Harvard Medical School | |
| 01/30/2015 | Journal Club- Bob Kesterson | UAB | |
| 02/06/2015 | No Seminar | ||
| 02/13/2015 | No Seminar | ||
| 02/20/2015 | Journal Club- Wei Zhang | UAB | |
| 02/27/2015 | No Seminar | ||
| 03/06/2015 | Matt R. Kaeberlein, Ph.D. | University of Washington | |
| 03/13/2015 | Rocio Moran, MD | Associate Staff, Cleveland Clinic | |
| 03/20/2015 | Journal Club-Haley D. Albright | ||
| 03/27/2015 | Spring Break | ||
| 04/03/2015 | Spring Break | ||
| 04/10/2015 | Bhupendra Singh, Ph.D. | Instructor, University of Alabama at Birminhgam | |
| 04/17/2015 | Randal Voss, Ph.D. | Professor, Biology, University of Kentucky | |
| 04/24/2015 | Day Before Commencement | ||
| 05/01/2015 | No Seminar | ||
| 05/08/2015 | Journal Club- Ying Peng | UAB | |
| 05/15/2015 | Anita Hjelmeland, Ph.D. | Assistant Professor, UAB | |
| 05/22/2015 | No Seminar | ||
| 05/29/2015 | Journal Club- Justin Avery | UAB |
