Genetics and Genomics Seminar Series

2021-2022

 

Archive

  • 2021-2022
    Friday, Sept. 3, 2021

    “Genetic Testing of Neurofibromatosis” 
    Juan Dong, PhD
    Associate Professor, Department of Genetics
    Director, Medical Genomics Laboratory


    Friday, Sept. 3, 2021

    “Mitochondria in Health and Disease”
    Keshav K Singh, Ph.D.
    Joy and Bill Harbert Endowed Chair in Cancer Genetics
    Professor of Genetics, Pathology and Environmental Health


    Friday, Aug. 27, 2021

    “Patient Specific Neurofibromatosis Type 1 Animal Models: Translational Studies and Therapeutic Approaches”
    Robert Kesterson, Ph.D.
    Professor with Tenure
    Department of Genetics
    University of Alabama at Birmingham


    Friday, Aug. 20, 2021

    “Genetic and Epigenetic Regulation of Heart Development”
    Kai Jiao, MD, PhD 
    Professor and Interim Director, Research 
    Department of Genetics


    Friday, July 23, 2021

    “DNA replication initiation and genome instability” 
    Anindya Dutta M.D., Ph.D.
    Professor/Chairman, Department of Genetics at UAB 


    Friday, July 16, 2021

    “Microbiome, metabolome, multi-omics…hype or path to precision biomedicine?”
    Tatiana T. Marquez Lago, Ph.D.
    Associate Professor
    Department of Genetics


    Friday, July 9, 2021

    “Genomic tools for third-generation sequencing data analysis” 
    Zechen Chong, Ph.D. 
    Assistant Professor, Genetics and Informatics Institute at UAB 


    Friday, July 2, 2021

    “Using CRISPR to Create Precision Animal Models” 
    Laura J. Lambert, Ph.D. 
    Assistant Professor, Department of Genetics 

  • 2020-2021
    Friday, May 21

    “Protein monoaminylation in brain: novel mechanisms of neural development, plasticity and disease” 
    Ian S. Maze, Ph.D. 
    Associate Professor 
    Friedman Brain Institute, Nash Family Department of Neuroscience 
    Icahn School of Medicine at Mount Sinai in New York City 


    Friday, May 14

    “Novel Mechanisms of Oncogenesis and Metastasis”
    Mick D. Edmonds, MS, Ph.D.
    Assistant Professor
    UAB Department of Genetics


    Friday, May 7

    “Phenomic Modeling”
    John Hartman, M.D.
    Associate Professor, Department of Genetics


    Friday, April 23

    “Direct Cardiac Reprogramming: How to Create New Cardiomyocytes?”
    Yang Zhou, Ph.D.
    Assistant Professor
    UAB Department of Biomedical Engineering


    Friday, March 5

    “Investigating Key Genetic Regulators in Small Cell Lung Cancer”
    Michael Kareta, Ph.D. 
    Associate Scientist 
    Sanford Research, Sioux Falls, SD


    Friday, January 15

    “Pathophysiological Basis and Mitigation for Cardiometabolic and Genetic Disorders” 
    Girish C. Melkani, Ph.D. 
    Associate Professor 
    Department of Pathology. Division of Molecular and Cellular Pathology 
    University of Alabama at Birmingham 


    Friday, December 11

    “Epithelial FOXP3-regulated network and targeted cancer therapies” 
    Lizhong Wang, Ph.D. 
    Associate Professor 
    UAB Department of Genetics


    Friday, November 20

    “Feasibility and Potential Impact of Exon Skipping as a Therapeutic for Neurofibromatosis Type I (NF1)” 
    Deeann Wallis, Ph.D. 
    Associate Professor
    UAB Department of Genetics 


    Friday, November 6

    “Sifting through Data from Clinical Genomes - When is a Case 'Solved'?” 
    Elaine Lyon, Ph.D. 
    Research Faculty Investigator, HudsonAlpha 
    Huntsville, Alabama


    Friday, Oct. 23

    “Mitochondria Based Priming of Stem Cell Self-Renewal: From Basic Science to its Translation” 
    Kasturi Mitra, Ph.D. 
    Assistant Professor. Department of Genetics 
    Co-Director, GGSC Undergraduate Program 


    Friday, Oct. 16

    “UAB Genomic Medicine” 
    Bruce R. Korf, M.D., Ph.D. 
    Wayne H. and Sara Crews Finley Endowed Chair in Medical Genetics 
    Associate Dean for Genomic Medicine, UAB School of Medicine 
    Chief Genomics Officer, UAB Medicine 

  • 2019-2020

    Friday, February 28 | “Understanding and Targeting Glioblastoma Environmental Effects: A Focus on Glucose Transporters” | Anita Hjelmeland, Ph.D., Associate Professor, Department of Cell, Development and Integrative Biology, University of Alabama at Birmingham 


    Friday, December 13 | “Targeting α2AAR: Solution for Alzheimer’s Disease” | Qin Wang, Ph.D., Professor, Department of Cell, Developmental and Integrative Biology, UAB


    Friday, December 6 | “Bioactive Retinoic Acid: Gene knockouts reveal unexpected roles” | Natalia Y. Kedishvili, Ph.D., Professor, Department of Biochemistry and Molecular Genetics, UAB


    Friday, November 22 | “Selective RANK Signaling Pathways as Novel Drug Targets for Breast Cancer Prevention” | Xu Feng, Ph.D., Professor, Department of Pathology 


    Friday, November 15 |“Population Genetics in an era of Precision Medicine” Eimear Kenny, Ph.D., Director, Center for Genomic Health, Associate Professor of Medicine, Associate Professor of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai 


    Friday, November 8 | “The identification and targeting of novel oncogenic ncRNA in human cancer” | Mick Edmonds, Ph.D., Assistant Professor, Genetics Research Division, Department of Genetics, UAB


    Friday, November 1 | "Computational Drug Repositioning Strategies for Precision Medicine 2.0" | Jake Chen, Ph.D., Chief Bioinformatics Office, Professor, Department of Genetics, Informatics Institute, UAB


    Friday, October 25 | “Mathematical modeling: Aiding biomedical discoveries" | Andre Leier, Ph.D., Assistant Professor, Department of Genetics, Assistant Professor, Department of Cell, Developmental and Integrative Biology, Associate Scientist, O’Neal Comprehensive Cancer Center, Member, Gregory Fleming James Cystic Fibrosis Research Center 


    Friday, October 18 | “Clinical Application of Genome Sequencing: The Children’s of Alabama Experience” | Anna C.E. Hurst, M.D., MS, FACMG, Assistant Professor,Department of Genetics,UAB


    Friday, September 27 | “Fluid-Mosaic Membrane in Aging, Disease and Mitochondrial Function and The use of Membrane Lipid Replacement to Reduce Fatigue, Pain and Other symptoms while Improving Mitochondrial Function” | Garth Nicolson, Ph.D., M.D., Professor Emeritus, President and Founder, The Institute for Molecular Medicine, Huntington Beach, CA


    Friday, September 13 | “From Genetic to Pharmacological Inhibition of TXNIP- Effects on Diabetes” | Anath Shalev, M.D., Professor of Medicine - Endocrinology, Diabetes & Metabolism, Nancy R. and Eugene C. Gwaltney Family Endowed Chair in Juvenile Diabetes Research, Director, UAB Comprehensive Diabetes Center 


    Friday, September 6 | “Genetic and epigenetic regulation of Duchenne muscular dystrophy” | Matthew S. Alexander, Ph.D., Assistant Professor, UAB Pediatric Neurology

  • 2018-2019

    Friday, May 17 | “Implementation of a Personalized Medicine Program Across a Community Health System” | Peter J. Hulick, M.D., MMSc, FACMG, Medical Director, Mark R. Neaman Center for Personalized Medicine Division, Head, Center for Medical Genetics NorthShore University HealthSystem, Clinical Assistant Professor, University of Chicago, Pritzker School of Medicine


    Friday, May 10 | “STAT3: From Fundamental Discoveries to Novel Targeting Platforms” | Hua Yu, Ph.D., Billy and Audrey L. Wilder Professor in Tumor Immunotherapy, Associate Chair and Professor, Department of Immuno-Oncology, Co-leader, Cancer Immunotherapeutics Program, City of Hope Comprehensive Cancer Center


    Friday, May 3 | “InterGenomic Cross Talk Underlying Aging and Cancer” | Keshav K. Singh, Ph.D., Joy and Bill Harbert Endowed Chair in Cancer Genetics and professor, Department of Genetics University of Alabama at Birmingham


    Friday, April 19 | “Enhancing Precision Oncology at UAB” | Eddy S. Yang, M.D., Ph.D., Professor, Vice Chair for Translational Science, Department of Radiation Oncology, University of Alabama at Birmingham


    Friday, April 12 | “Genetics and Epigenetic Regulation of Heart Development in Mice” | Kai Jiao, M.D., Ph.D., Associate Professor, Department of Genetics, Genetics Research Division, University of Alabama at Birmingham


    Friday, March 22 | “The Impact of Geometry, Diffusion Barriers and Stochasticity in Cell Polarity and Protein Dynamics” | Tatiana Marquez-Lago, Ph.D., Associate Professor, Department of Genetics, Research Division, University of Alabama at Birmingham


    Friday, March 15 | “Functional characterization of human disease-associated gene variants using the vertebrate animal model Xenopus laevis” | Chenbei Chang, Ph.D., Professor, Department of Cell, Developmental and Integrative Biology, UAB


    Friday, March 8 | “RAS and the Plasma Membrane: A Complicated Relationship” | John Hancock, MA MB BChir PhD ScD MRCP FRACP, Professor and Chairman, Department of Integrative Biology and Pharmacology, Executive Director, The Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center


    Friday, February 22 | “Epithelial Homeostasis in Development and Disease” | Ian G. Macara, PhD, Professor and Louise B. McGavock Chair, Department of Cell and Development Biology, Vanderbilt University Medical Center


    Friday, February 15 | “Structural Variations of the Immunoglobulin Receptors and
    Clinical Phenotype” | Robert P. Kimberly, M.D., Director, Center for Clinical and Translational Science University of Alabama at Birmingham


    Friday, February 1 | “A Novel Technology Developed at UAB for Phenomic Research and Drug Discovery” | John L. Hartman IV, M.D., Associate Professor, UAB Department of Genetics


    Friday, January 18 | "Polycystic Kidney Disease-Treatment Options Update" | Michal Mrug, M.D., Professor of Medicine, Department of Nephrology


    Friday, January 11 | “The algorithm for precision medicine” | Matthew Might, Ph.D., Professor of Computer Science, Director, UAB’s Hugh Kaul Precision Medicine institute, University of Alabama at Birmingham


    Friday, December 14 | “Molecular profiling in ovarian cancer” | Rebecca C. Arend, M.D., Assistant Professor, Department of Obstetrics and Gynecology, University of Alabama at Birmingham


    Friday, December 7 | “Epithelial-mesenchymal Transition in Breast Cancer Progression and Metastasis” | Binhua (Peter) Zhou, M.D., Ph.D., Co-Director, Center of Biomedical Research Excellence in Cancer and Metabolism, University of Kentucky, Lexington, KY


    Friday, November 30 | "A Mitochondrial Etiology of Common 'Complex' Diseases" | Douglass C. Wallace, Ph.D., Professor, Department of Pathology and Laboratory Medicine, University of Pennsylvania 


    Monday, November 19 | "Design and evolution of trans-splicing group I intron ribozymes" | Ulrich F. Muller, Ph.D., Associate Professor, Department of Chemistry and Biochemistry, University of California at San Diego


    Friday, November 2 | “Unraveling the complex roles of SIN3 in breast cancer metastasis”| Douglas R. Hurst, Ph.D., Assistant Professor, Department of Pathology, University of Alabama at Birmingham


    Friday, October 19 | "Patient-Specific NF1 Rodent Models & Gene Correction Therapies" | Robert A. Kesterson, Ph.D., Professor, Department of Genetics, UAB


    Friday, October 12 | "The ELMOD family of ARF family GAPs: roles in mitochondria, cell cycle, ciliogenesis, and transcriptional regulation" | Richard A. Kahn, Ph.D., Professor, Department of Biochemistry, Emory University

  • 2017-2018

    March 9, 2018 | Phillip Owens, Ph.D. | University of Colorado

    March 16, 2018 | Richard Finnell, Ph.D. | Baylor College of Medicine

    March 23, 2018 | Anthony Wynshaw-Boris, M.D., Ph.D. | Case Univeristy

    April 4, 2018 | Nita Limdi, PharmD, Ph.D. | UAB

    April 13, 2018 | Chulan Kwon, MS, Ph.D. | John Hopkins University

    April 20, 2018 | Merry-Lynn McDonald, Ph.D. | University of Alabama at Birmingham 

    May 4, 2018 | Mikhail Alexeyev, Ph.D., I University of South Alabama

    May 11, 2018 | Jiangbing Zhou, Ph.D. I  Yale University

  • 2016-2017

    Date

    Speaker

    Institution

    Title

    9/2/2016 Margaret R. "Peggy" Wallace Indiana University  Molecular and Cellular Studies of Neurofibromatosis 1
    9/9/2016      
    9/16/2016 Vidu Garg, MD Nationwide Children's Hospital  Insights into the genetics of congenital heart disease:
    From human genetics to mouse models
    9/23/2016 STATE DEPT MEETING     
    9/30/2016      
    10/7/2016 Jake Chen Journal Club  
    10/14/2016 IMMERSON COURSE     
    10/21/2016      
    10/26/2016      
    11/4/2016 Gabrielle Geddes, M.D. Medical College of Wisconsin/ Children's Hospital of Wisconsin  Ciliopathies and Congenital Heart Disease
    11/11/2016  Patty Sanderson  Journal Club  
    11/18/2016 SCIENTIFIC RETREAT    
    11/25/2016      
    12/2/2016  Brian Spurlock Journal Club Mechanisms of Autophagy as discovered by Dr. Yoshinori Oshumi Nobel Prize in Physiology or Medicine, 2016
    12/9/2016 Sophie Astrof, PhD Thomas Jefferson University Cell type-specific function of fibronectin in cardiovascular development
    12/16/2016      
    12/30/2016      
    1/6/2017

     Li, Yi, PHD

    *This lecture will take place from 2 - 3 p.m. in the Finely Conference Room

    Baylor College of Medicine`  Unexpected players in cancer metastasis
    1/13/2017 Joy Dean Journal Club  
    1/20/2017      
    1/27/2017      
    2/3/2017 Benjamin Tu, PhD  UT-Southwestern University  A metabolic vulnerability of tumors revealed by yeast
    2/10/2017      
    2/17/2017 Jariya Upadiya  Journal Club  Fox transcription factors in cardiovascular development
    2/24/2017 Barbara K Burton MD  Ann & Robert H. Lurie Children’s Hospital of Chicago   Lysosomal Acid Lipase Deficiency
    3/3/2017 RARE DISEASE SYMPOSIUM     
    3/10/2017 Dr. Kume Tsutomu   Northwestern University   Fox transcription factors in cardiovascular development
    3/17/2017 Bruce Walcheck University of Minnesota Regulating Receptor Levels on Leukocytes to Improve Their Function During Disease
    3/24/2017 Stephen Dalton   University of Georgia   “MYC coordinates metabolic control with pluripotent stem cell fate decisions”
    3/31/2017      
    4/7/2017 Dr. David Gutmann Washington Univ Neurofibromatosis Center   
    Neurofibromatosis: New Insights from an Old Gene
    4/14/2017 Danny Welch, PhD Univ of Kansas Medical Center The forgotten genome: Surprising roles of mitochondria in cancer metastasis.
    4/21/2017  Genetics Graduation - Robert Marion Albert Einstein College of Medicine  
    4/28/2017 Deborah Yelon Univ of California San Diego  “Molecular Mechanisms Regulating Cardiac Architecture in Zebrafish”
    5/5/2017 Dr. Prabhat Goswami      A redox cycle within the cell cycle: ring in the old with the new.
    5/12/2017 Deeann Wallis, PhD   Journal Club   
    5/19/2017 IMMERSION COURSE    
    5/26/2017 Shizen (Emily) Wang, Ph.D Seminar Series  “Cancer-derived extracellular miRNA in breast cancer metastasis”.
    6/9/2017 Dr. Melissa Harris    Uncovering gene regulatory networks for somatic stem cell self-renewal.
    9/29/2017 Dr. Elizabeth Worthey John Hartman Preparing for the Precision Medicine Revolution: Transforming Whole Genome Sequencing Data into Clinically Actionable Knowledge
  • 2015-2016
    Date  Speaker Institution Title
    09/04/2015      
    09/11/2015      
    09/18/2015 State Department Meeting     
    09/25/2015      
    10/02/2015      
    10/09/2015      
    10/16/2015 Journal Club-
    Justin Avery
    UAB  
    10/23/2015 Dr. Sunjung Kim   Children's National Medical Center  "The Role of Tumor Suppressor genes in Central Nervous System (CNS) Disorder
    10/30/2015  Deeann Wallis, Ph.D Texas  A&M University "High-Throughput Differentiation and Screening of a Library of Mutant Stem Cell Clones Defines New Host-Based Genes Involved in Infection'
    11/06/2015 Journal Club-
    Ved Prakash Mooga
    UAB  
    11/13/2015 Areeg El-gharbawy University of Pitsburg  
    11/20/2015      
    11/27/2015 Thanksgiving holiday    
    12/04/2015 Journal Club-
    Akila Subramanium
    UAB  
    12/11/2015 Joy Lincoln , Ph.D
    Nationwide Children's Hospital Research Institute  
    12/18/2015 Stanley Lei Qi, PhD  Stanford University  
    12/25/2015 Holiday    
    01/01/2016 Holiday     
    01/08/2016      
    01/15/2016 Day before MLK Weekend     
    01/22/2016 Journal Club -
    Kasturi Mitra, Ph.D
     UAB  
    01/29/2016  Ivan Moskowitz, MD, PhD University of Chicago  "Gene Regulatory Networks in Cardiac Development and Homeostasis"
    02/05/2016 Mick Edmonds, PhD, MS   Vanderbilt University Medical Cente  
    02/12/2016 Cancelled- Rescheduled for March 4.     
    02/19/2016 Toren Finkel  NIH  "Mitochondria and Aging"
    02/26/2016 Joy Lincoln , Ph.D  Nationwide Children's Hospital Research Institute "Exploring heart valve endothelial cell dynamics"
    03/04/2016  Journal Club- 
    Ashley Turner
     UAB  
    03/11/2016 Stanley Lei Qi, PhD   Stanford University "CRISPR/Cas9 for complex genome regulation and disease modeling"
    03/18/2016 Journal Club-
    Austin Hamm
     UAB  
    03/25/2016 Spring Break    
    04/01/2016 Spring Break     
    04/08/2016 Vishal Gohil  Texas A & M University "Discovering novel mitochondrial disease genes by integrative genomics"
    04/15/2016 Journal Club-
    Sean Santos
     UAB  
    04/20/2016 Woojin An, Ph.D.,  University of Southern California   Chromatin dynamics and gene regulation”
    04/22/2016 Todd Lowe, Ph.D.   University of California Santa Cruz  Unraveling the Complex Roles for 500+ Human tRNA Genes and their Ubiquitous Small RNA Fragments
    04/29/2016 Maria Alejandra San Martin, PhD   Emory University  “Diverse roles of NADPH oxidases in the VSMC phenotype” 
    05/06/2016  Anil Shanker, PhD Meharry Medical College School of Medicine  "Preventing Immune Escape Variants of Cancer"
    05/13/2016      
    05/20/2016 Brian Kennedy, PH.D. / LRC-235   Buck Institute for Aging  “The Age of Aging – Can We Intervene?”
    05/27/2016 Jing Yang PhD  University of California, San Diego  "Epithelial-Mesenchymal Plasticity in Carcinoma Metastasis"
    06/17/2016  Journal Club-
    Anna Hurst
     UAB  
  • 2014-2015
    Date Speaker Institution Title
    09/12/2014 Bruce Korf, M.D., Ph.D. Professor and Chair, Department of Genetics, UAB State of the Department Address
    09/19/2014 No Seminar    
    09/26/2014 Rebecca Dodd, Ph.D. Senior Research Associate, Duke University Medical Center  "New Mice for Old Questions: Modeling Soft-tissue Sarcoma"
    10/03/2014  No Seminar    
    10/10/2014 Todd Nystul, Ph.D. Assistant Professor, University of California San Francisco  "To Be (Stem) or Not to Be: Polarity and pH Define Cell Fate in an Epithelial Stem Lineage"
    10/17/2014 Becky Nagy, MD, LGC Assistant Professor, The Ohio State University  "The Use of Next Generation Sequencing in Novel Gene Discovery: A Tale of Two Cities"
    10/24/2014 Journal Club- Trevor Carden  UAB  
    10/31/2014 Sean Wu, MD, Ph.D  Professor, Stanford University "Molecular Regulation of Cardiac Development: Implications in Regenerative Therapy"
    11/07/2014 Hudson Alpha Retreat- NO SEMINAR N/A N/A
    11/14/2014 Journal Club-Anil Challa UAB  
    11/21/2014 Anil Challa, Ph.D  Instructor, University of Alabama at Birmingham  
    11/28/2014 Thanksgiving Holiday N/A N/A
    12/05/2014 Hyeong-Reh Choi Kim, Ph.D.  Assistant Professor, Wayne State University  "A Novel Function of PDGF D in Prostate Cancer Bone Metastasis: New Biology of an Old Growth Factor Family Member"
     12/12/2014  No Seminar    
     12/19/2014 Journal Club- Warren L Simmons UAB  
     12/26/2014 Christmas Holiday  N/A  N/A
     01/02/2015 New Years Holiday  N/A  N/A
    01/09/2015  Mark Gillespie, Ph.D. Professor and Chairman Dept. of Pharmacology, University of South Alabama  
     01/16/2015 MLK Holiday N/A N/A
     01/23/2015 William Pu, MD.  Harvard Medical School  
     01/30/2015 Journal Club- Bob Kesterson  UAB  
    02/06/2015 No Seminar    
    02/13/2015 No Seminar    
     02/20/2015 Journal Club- Wei Zhang UAB  
     02/27/2015 No Seminar    
     03/06/2015 Matt R. Kaeberlein, Ph.D.  University of Washington  
     03/13/2015 Rocio Moran, MD Associate Staff, Cleveland Clinic  
     03/20/2015 Journal Club-Haley D. Albright    
    03/27/2015 Spring Break    
     04/03/2015 Spring Break    
     04/10/2015 Bhupendra Singh, Ph.D. Instructor, University of Alabama at Birminhgam  
     04/17/2015 Randal Voss, Ph.D.  Professor, Biology, University of Kentucky  
    04/24/2015 Day Before Commencement    
     05/01/2015 No Seminar    
     05/08/2015  Journal Club- Ying Peng UAB  
     05/15/2015 Anita Hjelmeland, Ph.D.  Assistant Professor, UAB  
     05/22/2015 No Seminar    
     05/29/2015 Journal Club- Justin Avery UAB