Ravi Bhatia 2014Rank:  
Professor of Medicine
Division Director, Hematology/Oncology
Deputy Director, UAB Comprehensive Cancer Center
 
Division:            
Hematology & Oncology

Campus Address:   
NP 2555

Mailing Address:   
1720 2nd Avenue South, NP2540
Birmingham, AL 35294-3300

Phone: (205) 934-9591



For an appointment, call (205) 934-9999 or toll free 1 (800) UAB-8816.

Departmental Affiliation(s):
Primary: Medicine

Medical School:
All India Institute of Medical Sciences, New Delhi, India

Internal Medicine Residency:
All India Institute of Medical Sciences, New Delhi, India

Fellowship:
Fellowship in Hematology/Oncology from University of Minnesota, Minneapolis


Awards and Honors:
Stohlman Scholar of the Leukemia and Lymphoma Society
Elected, American Society of Clinical Investigation, 2006
Leukemia and Lymphoma Society, Scholar in Clinical Research Award, 2002
NIH FIRST Award, 1996
Watson Award-University of Minnesota, 1996
American Society of Clinical Oncology, Young Investigator Award, 1995
Frank Trobough Award of the American Federation for Clinical Research, 1991

MB BS:
Institute Gold Medal for the best graduate of the year, 1983
First position in the first and second professional examinations
Katherine Sorel Prize for the best student in Pediatrics
Sardari Lal Kalra Gold Medal for the best student in Microbiology
First position in Anatomy, Pathology and Microbiology
Forensic Medicine and Internal Medicine


Biosketch:
Positions and Employment:
May 2005 – December 2014
Professor
Director, Division of Hematopoietic Stem Cell and Leukemia Research
Co-Director, Hematological Malignancies Program, City of Hope Comprehensive Cancer Center
Department of Hematology/HCT
City of Hope National Medical Center
Duarte, CA

April 2004 – May 2005
Associate Professor
Department of Hematology/HCT
City of Hope National Medical Center
Duarte, CA

September 1996 – April 2004
Assistant Physician (equivalent to Assistant Professor)
Department of Hematology/HCT
City of Hope National Medical Center
Duarte, CA

September 1995 – August 1996
Clinical Assistant Professor
Division of Hematology
Department of Medicine
University of Minnesota


Major Research Interests

My research goals are to develop an improved understanding of abnormal regulation of malignant stem and progenitor cells in hematologic malignancies and to develop effective approaches to eliminate these cells to enhance outcomes for these cancers. In addition to being a practicing clinical Hematologist-Oncologist and Hematopoietic Cell Transplant physician, I have extensive experience in studying normal and malignant hematopoietic stem cell regulation in the translational laboratory setting. During my fellowship at the University of Minnesota, under the mentorship of Dr. Catherine Verfaillie and Dr. Philip McGlave, I studied mechanisms of microenvironmental regulation of normal and malignant hematopoiesis, and mechanisms of response and resistance of leukemia stem cells to therapy. After establishing my independent research program at City of Hope, I have continued to investigate mechanisms of regulation of normal and leukemia stem cell growth and therapeutic targeting of leukemia stem cells. My research goals are to develop an improved understanding of abnormal regulation of malignant stem and progenitor cells in hematologic malignancies and to develop effective approaches to eliminate these cells to enhance outcomes for these cancers. I was appointed as Director of the Division of Hematopoietic Stem Cell and Leukemia Research and co-Director of the Hematological Malignancies Program in the Comprehensive Cancer Center in 2006 to develop a basic and translational program in hematological malignancies and hematopoietic stem cells at our center. Since taking over this position, I have recruited and mentored an outstanding group of young faculty with a common interest in investigating mechanisms of regulation of normal stem cell growth; cellular and molecular mechanisms underlying hematopoietic cell transformation in patients with hematological malignancies; identification of critical therapeutic targets; and preclinical and clinical development of innovative, mechanism-based therapeutic interventions.


Research Description

Mechanisms of transformation and maintenance of leukemia stem cells
Therapeutic targeting of leukemia stem cells


Publications: See a listing of publications on PubMed, a service of the National Library of Medicine.

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