schoebProfessor Emeritus of Genetics



Address: Bevill Biomedical Research Bldg, room 273A
UAB
Birmingham, AL 35294
Telephone: (205) 934-2288
Email: trs@uab.edu


 

Publications

 

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Education


B.S., Oklahoma State University, Stillwater, OK, 1972
D.V.M.,Oklahoma State University, Stillwater, OK, 1974
M.S.,Oklahoma State University, Stillwater, OK, 1977
Ph.D.,University of Alabama at Birmingham, Birmingham, Al, 1981 


Research Interests


My primary interest is in use of genetically engineered and gnotobiotic mouse models in studies of mechanisms of inflammatory and other disease processes, particularly diseases of dysregulated immunity and inflammation (inflammatory bowel disease, lupus erythematosus, multiple sclerosis), genetic deficiency diseases and diseases of development (enzyme deficiencies, polycystic diseases, cystic fibrosis), respiratory disease, and renal disease. My area of expertise is in application of qualitative, semiquantitative, and quantitative anatomic pathologic techniques to phenotypic characterization of genetically engineered mice and to analysis of disease expression in animal models. I have over 40 years of experience in this area and in pathology of laboratory animals in general, and am certified in anatomic pathology by the American College of Veterinary Pathologists (1980). In addition, I have experience in management and experimental use of gnotobiotic mice and rats dating from 1977.