September 15, 2020

DAVID E. WELLS MEMORIAL SYMPOSIUM

September 15, 2020

Virtual

12:30pm

Welcome

 12:45pm

Student Presentation #1

Riegler

Dissecting the complex, integral role of necroptotic cell death during airway infection

Ashleigh Riegler

Lab: Carlos Orihuela

 1:15pm

Student Presentation #2

Kizziah

Molecular pirates use diverse strategies to redirect capsid size

James Kizziah

Lab: Terje Dokland

1:45pm 

Student Presentation #3

Barra

Islet encapsulation with tannic acid delays islet graft rejection

Jessie Barra

Lab: Hubert Tse

2:10pm

Break

3:00pm

David E. Wells Guest Lecturer

June Round

Microbiota-immune interactions that regulate intestinal health

June Round, PhD

University of Utah

4:00pm

Announcement of the of David E. Wells Research Award

4:15pm

Closing Remarks


 

June Round, Ph.D.
Associate Professor
Department of Pathology, Huntsman Cancer Institute
University of Utah

The mammalian immune system is charged with the task of recognizing microbial molecules and subsequently coordinating pathogen clearance. However, humans are host to a multitude of symbiotic microorganisms called the microbiota. This diverse consortium of bacteria take up residence on almost all environmentally exposed surfaces of the body, with the greatest diversity and number of organisms residing within the gastrointestinal (GI) tract. Since both pahtogenic and commensal microorganisms share similar molecular patterns, it remains unclear how host immune responses toward symbiotic bacteria are prevented. Diseases such as inflammatory bowel disease, (IBD) result from a loss of host tolerance to commensal bacteria, thus understanding the mechanisms by which the host tolerates the microbiota and in turn how the microbiota influences the host immune system is paramount toward gaining a deeper understanding of mucosal biology and developing therapies for the treatment of intestinal disease.