Where: BBRB 170 

 When: Tuesdays at Noon

 Date Name  Institution  Host  Area of Interest/Recent Publications Title
 September 5

Dr. Cheri Stabler   University of Florida Hubert Tse   Dr. Stabler's research centers on engineering translational biomaterial platform for cell therapies, particularly Type 1 diabetes.
September 12  David Wells Research Sympoium Lecture - Dr. Ellen Rothenberg   California Institute of Technology

Students and Dr. Lund   The Rothenberg group studies the molecular mechanisms that are responsible for developmental lineage choice as hematopoietic stem cells differentiate into T lymphocytes.  
September 19
Dr. Kelly Doran   University of Colorado  David Briles  Her main research areas seek to understand and how bacteria penetrate the bloodbrain barrier to cause meningitis, as well as how bacteria colonize the female reproductive tract prior to causing disease.  
September 26
Dr. Deborah Hogan,
co-sponsored by School of Dentistry 
 Dartmouth School of Medicine Hui Wu   We study how opportunistic pathogens adapt to host-associated environments, with a focus on the fungus Candida albicans, the bacterium and the microbes that they interact with in vivo. 

 Date Name  Institution  Host  Area of Interest/Recent Publications Title
 October 3
 Dr. Pamela Schwartzberg, MD, PhD National Human Genome Research Institute, NIH Dr. Fran Lund   Her laboratory's work has centered on the use of genetic, biochemical and cellular studies to understand T cell signaling, with a focus on pathways affected by primary immunodeficiencies.
October 10   Dr. Yizhi Jane Tao  Rice University Dr. Todd Green  Our laboratory is interested in the catalytic mechanisms of viral RNA polymerases and in how RNA viruses exert regulation over RNA synthesis through polymerase interactions with viral and cellular factors.  
October 17  Dr. Paul Bieniasz  Aaron Diamond  AIDS Research Center , The Rockefeller University Jamil Saad   Dr. Bieniasz seeks to define how host gene products influence the replication of retroviruses, with an emphasis on human and primate immunodeficiency viruses.
October 24
 Dr. Sabine Ehrt, PhD  Cornell University Michael Niederweis  To better understand the molecular basis for Mtb’sability to resist host defense mechanisms and  the metabolic environment Mtb faces within its host.    
October 31
 Dr. Solbodan Paessler  UTMB, Department of Pathology Ilya Frolov  The research in my laboratory has focused on viral pathogenesis, vaccine development and on development of animal models to test new vaccine candidates and antiviral drugs. My main research interest is in understanding the mechanisms by which emerging RNA viruses cause encephalitis, hemorrhagic fever, or respiratory diseases. 

 Date Name  Institution  Host  Area of Interest/Recent Publications Title
 November 7

  Susan Dubay Memorial Lecture - Dr. Daniel A. Portnoy  UC Berkley School of Public Health Dr. Fran Lund   Dr. Portnoy's lab has worked on the pathogenesis of Listeria monocytogenes for over two decades, topics ranging from basic aspect of physiology, cell biology of infection and innate and acquired immunity as well. 
November 14
 Dr. Melissa Kendall  University of Virginia School of Medicine in Charlottesville Microbiology grad students - Cathy  Yea Won Sung and Anukul Shenoy   My research examines signaling pathways that enable bacterial pathogens to sense and adapt to specific niches within a host to cause disease.
November 21
 Not holding Seminar -week of Thanksgiving      
November 28
 HOLDING / not currently avialable        

 Date Name  Institution  Host  Area of Interest/Recent Publications Title
December 5

 Dr. Ivaylo Ivanov  Columbia University Fran Lund  Our laboratory is interested in identifying specific examples of immunomodulatory interactions between commensals and the host as well as the underlying mechanisms.  
December 12 HOLDING/ not currently avialable     
December 19
HOLDING / not currently avialable       
December 26
Not holding Seminar -
week of Christmas break 

 Date Name  Institution  Host  Area of Interest/Recent Publications Title
 January 2

Not Holding Seminar -
week of New Year's 
January 9
Dr. Avery August 
Cornell University

 Amy Weinmann   We are interested in the role of Tyrosine Kinases (TKs) in regulating the immune response, with the goal of using this information to manipulate immune responses. We are specifically interested in the Tec families of nonreceptor TKs.  
January 16 Dr. Sallie Permar     Duke University Mark Walter  Dr. Permar's work focuses on maternal correlates of immune protection against vertical transmission of neonatal viral pathogens.  
January 23
  Dr. Tanecia Mitchell  UAB, Department of Urology Hubert Tse    Dr. Mitchell’s current research investigates the role of mitochondria and oxidative stress in immune cells from patients with kidney stone disease and interstitial cystitis/painful bladder syndrome. It is Dr. Mitchell’s hope that her research will provide relevant scientific information to help understand, prevent, and/or treat renal diseases and urological disorders.  
January 30 Dr. Yabing Chen   UAB, Department of Molecular and Cellular Pathology Dr. Jamil Saad    Regulation of vascular smooth muscle cells (VSMC) contributes significantly to the development of cardiovascular diseases, including atherosclerosis and pulmonary hypertension. Increased oxidative stress accelerates the progression of atherosclerosis and vascular calcification. Projects involve characterization of molecular signals that regulates osteogenic transcription factor Runx2 in vascular calcification, as well as mechanisms underlying Runx2 in modulating the pathogenesis of atherosclerosis and vascular calcification.   

February 2018
 Date Name  Institution  Host  Area of Interest/Recent Publications Title
 February 6

Dr. Cara Pager    University of Albany, State University of New York Dr Sunnie Thompson   Our lab is interested in the intracate ways  in  which Flavaviruses subvert host RNA metabolism paths, to avoid destruction of their genomes and promote viral gene expression  
February 13
Microbiology faculty recruit Dr. Felipe Santiago-Tirado   Washington  Univsersity Dr. Carlos Orihuela  Fungal pathogenensis   
February 20  Not available, MARX LECTURE Dr. Feng Zhang  Broad Institue of MIT and Harvard
Dr. Fran Lund    Our group is developing and applying molecular and optical technologies for probing brain function in health and disease.
February 27
Dr. Edward Swords   University of Alabama at Birmingham Dr . Fran Lund Host and Microbial Determinants of Bacterial Colonization and Persistence during Opportunistic Airway Infections

March 2018
 Date Name  Institution  Host  Area of Interest/Recent Publications Title
 March 6

Dr. Emma Teixeiro-Pernas    Univseristy  of  Missouri School of Medicine Beatriz Leon-Ruiz   In my lab we wish to understand the mechanisms that drive the generation of efficient memory T cells.  
March 12*
Dr. Rakesh Patel     UAB, Department of Pathology Michael Gray  We are interested in understanding what regulates the reactivity and function of reactive species and pursue this aim in the following contexts: interactions of nitric oxide and nitrite with red blood cells during normal physiological conditions and during inflammation associated with Sepsis and ischemia-reperfusion injury and the anti-inflannatry effects of dietary antioxidants   
March 20 Dr. Andre Ballesteros-Tato   UAB, Department of Medicine, Division of Clinical Immunology and Rheumatology Dr. Beatriz Leon-Ruiz  The focus of the research in my laboratory is to study the cellular interactions, the environmental cues and the molecular mechanisms that control the differential capacity of distinct populations of dendritic cells (DCs) to regulate effector, memory T cell responses and T follicular helper (Tfh) cell differentiation in different models of infection and autoimmune disease. In addition, we are studying the role of Tfh cells in Systemic Lupus Erythematosus (SLE or Lupus) and Rheumatoid arthritis (RA).   
March 27
Dr. Hao Shen   University of Pennsylvania  Allan Zajac We have a long-standing interest in basic questions related to generation of effective immune responses, mechanisms of protective immunity, and the establishment of long-term immunological memory.    

APRIL 2018
 Date Name  Institution  Host  Area of Interest/Recent Publications Title
 April 3

Dr. Carlos Oriheula, PhD  Department of Microbiology, UAB  Fran Lund  Dr.Orihuela's research focus has been the host-pathogen interactions responsible for the development of invasive pneumococcal disease (i.e transition of the bacteria from nasopharynx to lungs, lungs to bloodstream, bloodstream to tissues and central nervous system). Most recently this includes exploring how advanced age impacts innate immunity and characterization of the cardiotoxic events that occur during IPD.   
April 10
Dr. Max Nibert, MD, PhD    Harvard Medical School Elliot Leftkowitz  We are interested to define the biochemical and biophysical mechanisms by which non-enveloped viruses penetrate the cellular membrane barrier during entry.
April 17
Dr. Diane Mathis   Harvard Medical School Students in the graduate student Immunology Theme /  Dr. Louis Justement  Our lab works in the broad fields of T cell differentiation and tolerance/autoimmunity, translating mechanistic studies on mouse models to normal and diseased humans.    
April 24
Dr. Javier Campos-Gomez   Southern Research Fran Lund  His main research interest is in the field of infectious diseases, where he is focused on developing bacteriophage based therapies to treat or prevent viral and bacterial infectious diseases. This includes engineering filamentous phages for targeting and containing multidrug resistant and reemerging bacterial diseases and the use of phages as platforms to display antigens of important pathogens with vaccines purposes. 

May 2018
 Date Name  Institution  Host  Area of Interest/Recent Publications Title
May 1

Dr. Alice Prince  Columbia University  Carlos Orihuela  Our laboratory studies the interaction of the host and bacterial pathogens.  We have focused upon the host response to bacterial components and how this response is activated and regulated in both the airway and skin.   
May 8
Dr. Hai-hui Xue   Iowa University Dr. Hui Hu  We are interested in transcriptional and epigenetic regulation of T cell development and mature T cell responses to infections. Our current focus is on Tcf1 and Lef1 transcription factors in the Tcf/Lef family, their interacting partners including the - and -catenin coactivators and TLE corepressors.    
May 15
Dr. Jainmei Leavenworth    UAB, Department of Neurosurgery Jamil Saad or Fran Lund  Her main research interest is to understand the mechanisms of self-tolerance, focusing on molecular and cellular elements that regulate effector and regulatory cell subsets of the immune response. Her long-term goal is to seek effective strategies for cancer immunotherapy using mouse models and specimens from patients with malignant tumors, including gliomas.    
May 22
Dr. Vincent Racaniello  Columbia University Meagan Jenkins Eric Carlin Virology Graduate Students   Our research focuses on the interaction of viruses with the innate immune system, viral pathogenesis, and viral discovery in wild animals.  
May 29
Dr. Michael Gray   UAB, Department of Micrbiology Jamil Saad   We are particularly interested in the molecular biology of the symbiotic and probiotic bacteria that make up the healthy microbiome. Our current research focuses on the bacterial response to reactive chlorine stress.