Where: BBRB 170 

 When: Tuesdays at Noon

 
SEPTEMBER
Date Name  Institution  Host  Area of Interest/Recent Publications Title
Month and Day Speaker Name Institution Name Host Name This is the speakers area of interests. Title of their talk
Sept.  3, 2019 Michael Otto  NIAID, NIH  Hui Wu   Physiology of staphylococcal biofilms and biofilm-associated infection, molecular basis of immune evasion mechanisms in Staphylococci: expolymers, toxins, antimicrobial peptide resistance, community- and hospital-associated MRSA; virulence determinants and epidemiology, gene regulatory processes durring pathogen-host interaction  "Probiotics to Prevent S"tapthylococcus aureus Disease?"
Sept. 10, 2019  Patrick Griffin  Scripps Research  Mark Walter  mutational and ligand-mediated alterations in protein structural plasticity as well as quantitative SAR to faciliate lead optimization of molecules targeting therapeutic proteins,  also understandin stucture-function of nuclear receptors, enzymes, and G protein coupled receptors  "Hijacking molecular plasticity to fine tune nucelar receptor signaling: Chemical Biology and Precision Therapeutics"
Sept 16, 2019 Eva Harris,
Susan Dubay Memoerial Lecturer
Univ of Cal at Berkeley Fran Lund study of molecular viorology, pathogenesis, immunology, epidemiology, clincical aspectsand control of dengue, Zika, and chikungunya "Friend of Foe? Immunology and epidemiology of dengue and Zika"
Sept. 17, 2019    Eva Harris Univ. of Cal. at Berkeley   Virology Grad Students  study of molecular virology, pathogenesis, immunology, epidemiology, clinical aspects and control of dengue, Zika, and chikungunya  "The Flavivirus NS1 protein: Unraveling mechanisms of pathogenesis of dengue, Zika, and beyond"
Sept. 24, 2019 Janusz Kabarowski   UAB, Microbiology  John Kearney  study of lipids and lipoprotein metabolism in chronic infalmmatory disease, notably atherosclerosis and autoimmune disease  "Lipids, Vascular Inflammaton and Atherosclerosis in Space"


OCTOBER
Date Name  Institution  Host  Area of Interest/Recent Publications Title
Oct. 1, 2019   Maria Bartolomeo Grant  UAB, Dept of Ophthalmology and Visual Sciences  Allan Zajac  understanding the functional process of hematopoietic stem cells and how best to utilize human embryonic stem cells for vascular repair "Restructuring the gut microbiome for preventing diabetic vascular complications"
 Oct. 8, 2019          
Oct. 15, 2019   Arvind Varsani  Arizona State University  Elliot Lefkowitz  uses combination of traditional virology, microscopy, molecular and cellular biology techniques in conjunction with modern dequencing techniques, synthetic biology and bioinformatics to characterize viruses and understand their dynamics  "Virus Dynamics: Evolution, movement & the great unknown"
Oct. 22, 2019   Ralph Sanderson  UAB, Division of Moelcular & Cellular Pathology  John Kearney  how tumor-host cell interactions mediated by heparan sulfate and enzyme heparanase regulate the tumor microenvironment and to use that knowledge to design new cancer therapies  "Heparanase-mediated regulation of exosomes that promote tumor progression and chemoresistance"
Oct. 29, 2019  Lalita Shevde-Samant  UAB, Molecular & Cellular Pathology  John Kearney  understanding the process of metastasis and deepning our understanding of why cancer treatment fails and resistance develops,  "Targeting Hedgehog signaling to reprogram the tumor microenvironment"


NOVEMBER
Date Name  Institution  Host  Area of Interest/Recent Publications Title
Nov. 4, 2019   Fernando de la Cruz  Univ of Cantabria  Javier Campos Gomez bacterial conjugation and plamsid molecular genetics/biology "Plasmid taxonomy and the boundaries of horizontal gene transfer"
Nov. 12, 2019   Luisa Hiller  Carnegie Mellon Univ  Carlos Orihuela  microbial pathogenesis, combines comparative genomics, bioinformatics, and Phylogenetics to develop hypotheses on gene function, identifies genomic patterns and correlated these to microbial molecular behaviors and host responses  "Questions Budding at the Interface of Pneumococcus and the Human Host"
Nov. 19, 2019 
Nov. 26, 2019   No seminar


DECEMBER
Date Name  Institution  Host  Area of Interest/Recent Publications Title
Dec, 3, 2019   Champion Deivanayagam  UAB, Dept of Biochem & Mol. Genetics  John Kearney  Studying the surface proten structures of gram-positive bacteria, understanding the mechanistic aspects of adhesion  "Structural and functional studies on the oral streptococcal adhesive proteins"
Dec. 10, 2019   Remy Bosselut (cancelled, moved  to March 31, 2020)
 NIH Center for Cancer Research  Hui Hu  transcriptional control of T cell development and function, notably the gene expression programs whichb control the 'choice' by T cell precursors of the CD4 or CD8 lineage in the thymus and which perpetuate lineage differenetiation in mature T cells  "CD4 T cell responses to infection and cancer: early decisions and long-term plans"
Dec, 17, 2019   Chad Petit  UAB, Dept of Biochemistry and Molecular Genetics  Jamil Saad Structurally and biochemicall anaylsis of the influenza strain dependence of NS1 function, to elucidate structure-function relationships between NS1 and its cellular intercaction partners, understanding how influenza is bale ot evade the host immune response  "Structural and Functional Insights into Influenza NS1-mediated Antagoninsm of RIG-I Activation"
Dec. 24, 2019  No seminar        
Dec. 31, 2019 No seminar        


JANUARY
Date Name  Institution  Host  Area of Interest/Recent Publications Title
 Jan. 7, 2020  No seminar  
Jan. 14, 2020  Ryan Hunter  Univ of Minnesota  Jessica Scoffield  host-microbe interactions and characterizing the effect of in vivo environmental chemistry on the dynamics of polymicrobial infections  "When good bugs go wild: How commensal microbiota shape the development and treatment of chronic airway disease"
Jan. 21, 2020   RESCHUELED to May 12th Michael Imperiale  Univ of Michigan  Sunnie Thompson  molecular biology of BK polyomavirus, int he interplay between viral and host facotrs that lead to peristance or replication as well as viral genomic rearrangements that occur in patients with BKpyV disease  "The Pathway from BKPyV Persistence to Productive Replication"
Jan 28, 2020  Anthony Maurelli  Univ of Florida  David Briles  Pathogenic mechanisms of Shigella flexneri and Chlamydia ,  "Peptidoglycan Synthesis and Cell Division in Chlamydia"


FEBRUARY
Date Name  Institution  Host  Area of Interest/Recent Publications Title
 Feb. 4, 2020 Tomohiro Kurosaki  Osaka University  Pete Burrows  tracing the fate determination mechanism of B lymphocytes in immunity  "Fate decision germinal center B cell"
Feb. 11, 2020   Michael Imperiale rescheduled  Univ of Michigan Sunnie Thompson  molecular biology of BK polyomavirus, infection, persistence and  replication,  "The Pathway from BKPvY Persistence to Productive Replication"
Feb. 18, 2020   Louis Mansky  Univ of Minneapolis  Jamil Saad  fundamental understanding of viral mutagenesis and evolution, molecular and cellular aspects of viral particle assembly and transmission  "Visualizing human retrovirus particle biogenesis"
Feb. 25, 2020   Grant Jensen  California Institute of Technology  Rhea Derke, Rachel Andrews, Bacteriology Grad Students  uses Electorn Cryotograhpy to study the molecular architecture of microbial cells and HIV in  their native state, focusing on cell division, movement and secretion as well as the structure of HIV at all of its lifecycle  "Imaging cells in 3D with Electron cryotomography"


MARCH
Date Name  Institution  Host  Area of Interest/Recent Publications Title
Mar. 3, 2020  Akiko Iwasaki, Bertram Marx lecturer  Yale University School of Medicine  Fran Lund  Innate immunity, autophagy, inflammasomes, sexually transmitted infections, herpes simplex virus; human papillomavirus; respiratory virus iinfections, influenza infection, t-cell immunity, commensal bacteria  "Antiviral immunity at the mucosal surfaces"
Mar. 10, 2020  Bebhinn Treanor, cancelled rescheduled to Nov 17   University of Toronto, Scarborough  Fran Lund  understanding the cellular and molecular mechanisms of immune cell activation, focusing on the molecular mechanisms controlling the organization and dynamics of immune cell receptors and the functional significance for immune cell activation through the development of cutting edge optical microscopy  "Glycan-galectin interactions in the regulation of B cells"
Mar. 17, 2020   Matthew Bettin, cancelled, soon to be rescheduledi  Baylor College of Medicine  Hubert Tse  autoimmune diabetes, with specific focus on T cells and the T cell receptor role in autoimmune disease development  "Thymic Development  of a Self-Tolerant T-cell Repertoire"
Mar. 24, 2020   Kenneth Oestreich, cancelled rescheduled to Oct 27th, 2020  Virginia Tech Carilion  Beatriz Leon  defining the mechanisms by whihc transcription factors contribute to the cellular differentiation and function in the immune system  "Regulation of T helper cell differentiation programs by Ikaros zinc finger transcription factors"
Mar. 31, 2020  Remy Bosselut, Cancelled, soon to be rescheduled
 NIH Center for Cancer Research  Hui Hu  transcriptional control of T cell development and function, notably the gene expression programs whichb control the 'choice' by T cell precursors of the CD4 or CD8 lineage in the thymus and which perpetuate lineage differenetiation in mature T cells  "CD4 T cell responses to infection and cancer: early decisions and long-term plans"


APRIL
Date Name  Institution  Host  Area of Interest/Recent Publications Title
 Apr. 7, 2020  Narendra Wajapeyee, to be rescheduled  UAB, Biochemistry and Molecular Genetics Allen Zajac  understand key mechanims involved in the regulation gene expression and signal transduction pathways in cancer  
Apr. 14, 2020   Eric Ubil, on line vis Zoom  Meeting ID 360 474 114 password uab_micro   UAB, Microbiology  Michael Gray  Understanding how tumor secretions can inhibit the innate immune reponse and identifying therapies to restore anti-cancer immune activity  
Apr. 21, 2020   Moon Nahm To be rescheduled  UAB, Pulmonary, Allergy and Critical Care  Jamil Saad  studies diversity and immunity to pneumococcus capsule  
Apr. 28, 2020   Masakazu Kamata, to be rescheduled  UAB, Microbiology  Michael Gray  understanding why the host immune system is unable ot control HIV-1infections as well as malignant tumors and identifying novel therapeutic targets to augment immune reponses and restore antiviral or anticancer immunity  


MAY
Date Name  Institution  Host  Area of Interest/Recent Publications Title
May 5, 2020  Michael Gray UAB, Microbiology  Terje Dokland  bacterial genetics and physiology, how bacteria sense and respond to changes in thier environments  "Gray Lab Update: Bleach, Bacteria and the Molecular Mechanisms of Stress Response"
May 12, 2020   Shannon Kahan
 UAB, Microbiology Allan Zajac  focused on immune repsonses to infections, investigating cell-mediated immune repsonses,  "Intrinsic and Extrinsic Signals that Direct Anti-viral CD8 T Cell Fates"
May 19, 2020  Sunnie Thompson
 UAB, Microbiology
 Michael Gray
 virus-host interactons and cellular mechanisms of translation intiation,
 "Insights into Polyomavirus and Coronavirus Manipulations of the Cell Cycle"
May 26, 2020   Colin Reily  UAB, Medicine-Nephrology  Jan Novak 
 IgA Neuropathy, glycosylation   "IgA and Glycosylation in IgA Nephrology" 

JUNE
Date Name  Institution  Host  Area of Interest/Recent Publications Title
June 9, 2020       
June 30, 2020   Carlos Orihuela
 UAB, Microbiology Michael Gray  host-pathogen interactions that underlie development of invasive pneumococcal disease  




JULY
Date Name  Institution  Host  Area of Interest/Recent Publications Title
July 14, 2020  Fran Lund, to be rescheduled UAB, Microbiology  Carlos Orihuela  identify key players that suppress or exacerbate mucosal inflammatory responses with the long-term goal of developing therapeutics to treat immunopathology associated with chronic infectious, allegeric and autoimmune disease  
July 28, 2020  Jamil Saad  UAB, Microbiology Terje Dokland  elucidating molecular mechanisms if HIV assembly  "Mechanisms of HIV-1 Assemb ly Through the Lens of Structural Biology"



AUGUST
Date Name  Institution  Host  Area of Interest/Recent Publications Title
Aug 11, 2020   Michael NIederweis
 UAB, Microbiology  Joel Glasgow  understanding the functions, structures, roles in tuberculois of outer membrane novel proteins "The Tuberculois Toxin"  
Aug 25, 2020   Ilya Frolov
 UAB, Microbiology Terje Dokland  Alphavirus genome replication and particle assembly  "Alphaviruses hijack host proteins for genome replication"