- Published on March 25, 2014
The paper, originally published in Science, April 1994, is regarded as a classic in the field. It has been republished with additional commentary included. Papers selected as Pillars of Immunology features give younger immunologists the opportunity to see what research has come before and how it has led to research today. Pillars articles are published in the first issue each month of The Journal of Immunology.
As part of its centennial celebrations, The American Association of Immunologists has made available the collected Pillars of Immunology commentaries in a downloadable format.
- Published on March 21, 2014
Chang, a Biochemistry and Biology major, plans to pursue an M.D./Ph.D. that will allow him to enter academic medicine and teach at a leading medical research university. His work in the Saad lab involves further elucidating the structural basis for Fas-mediated apoptosis and investigating the role of a point mutation in the Fas protein that may reveal the mechanism of inhibition for the Fas pathway.
The Barry Goldwater Scholarship and Excellence in Education Program was established by Congress in 1986 to honor Senator Barry Goldwater, who served his country for 56 years as a soldier and statesman, including 30 years of service in the U.S. Senate. The purpose of the Foundation is to provide a continuing source of highly qualified scientists, mathematicians, and engineers by awarding scholarships to college students who intend to pursue research careers in these fields.
- Published on March 14, 2014
Shane Kelly, a graduate student in Dr. David Bedwell’s lab, shows the art in his cells with three fluorescent confocal micrographs of cheek cells that he entered in the UAB School of Medicine Art Show. Kelly’s works of art are currently on display in the UAB Edge of Chaos.
Read more at “A self-portrait in cells: Grad student gets cheeky with art show entries.” (UAB The Mix, Thursday, March 13, 2014)
- Published on March 12, 2014
Currently, she is working on the mechanisms by which lineage-specifying transcription factors regulate cell fate decisions in development. “A major focus of the research in my lab is on the T-box and BTB-ZF transcription factor families, which are required to promote cellular transitions in numerous developmental systems, ranging from early embryogenesis to immune cell fate. We are also interested in defining the mechanisms by which epigenetic patterns are established in a cell-type and activation-state specific manner. Collectively, our mechanistic studies will provide new insight into many human diseases that are associated with dysregulation of these pathways, including a major emphasis on blood cancers, autoimmunity, and birth defects.”
During this time of economic challenges, Weinmann takes her job as mentor seriously. She says that it is easy to get discouraged when funding is so limited, but a person must not accept the word can’t. “Science is do-able,” she says. “Passion comes from within. Nobody can take your passion away from you.” She enjoys watching students learn how to drive their own science. “Early on, it’s much more hands-on, but eventually it starts to flip and by the end, the student knows way more than I do. It’s a proud moment when they’re on their own.”
In her spare time, Weinmann follows professional sports (especially the Minnesota Vikings), and she herself can spike a mean volleyball, having played volleyball in high school and college. She says, “the mental discipline of sports fits well with science. It’s always a work in progress; you should be proud of what you’ve accomplished, but at the same time strive to do better and learn more.”
- Published on March 12, 2014
In 2012, Jiang became a research investigator at the University of Michigan, where she worked two years on the host-pathogen interactions of a human DNA tumor virus, BK polyomavirus (BKPyV). Now, as assistant professor in the microbiology department at UAB, she continues to search for a better understanding of the BKPyV life cycle to aid in the design of novel, more efficient anti-viral strategies.
“BKPyV infection is ubiquitous in the human population and occurs during early childhood,” says Jiang. “Primary infection with BKPyV is followed by dissemination to the kidney and urinary tract, in particular to kidney tubule epithelial cells and urinary tract epithelial cells, where the virus establishes a lifelong persistent infection. This infection remains asymptomatic in immunocompetent individuals, but under conditions of immunosuppression, BKPyV can undergo reactivation resulting in viral shedding in the urine and may eventually lead to severe diseases such as polyomavirus-associated nephropathy (PVAN) in renal transplant patients and hemorrhagic cystitis in bone marrow transplant recipients.”
Jiang says that no specific antiviral drugs for BKPyV infection are currently available, although the incidence of BKPyVrelated disease has greatly increased in the last few years. The immune components that are involved in controlling BKV persistence and reactivation are not well defined. As a new assistant professor, Jiang is looking to fill several positions in her lab. She enjoys sharing her excitement for research with students just entering the field. “It is important for students to learn how to do science, to think critically, and to establish their independence,” says Jiang.
- Published on February 28, 2014
Kearney’s work has brought worldwide recognition to UAB. He is an internationally recognized expert in monoclonal antibodies and their source: immune cells known as B cells that produce the antibodies necessary to fight off infections and other immune threats.
Kearney came to UAB as a postdoctoral fellow in 1974 and joined the microbiology faculty in 1977. In addition to his primary faculty appointment in the microbiology department, Kearney holds several other appointments at UAB including senior scientist in the UAB Comprehensive Cancer Center and UAB Center for Disease Preparedness, as well as a professor in the Division of Developmental and Clinical Immunology.
- PostDocs Score Big at Research Day
- Yother Receives Diversity Award
- Potential New Drug Pathway Target for Battling Mycobacterium Tuberculosis
- 5th Southeastern Mycobacteria Meeting
- Bliss Chang Invited to Present His Work at Posters on the Hill
- Kabarowski Among UAB Researchers to Establish New Imaging Method
- Congratulations to Our Recent Graduates
- Briles Elected to National Academy of Inventors
- SOM Nominates Yother for 2014 Diversity Award
- 2013 UAB Microbiology Research Retreat
- Bedwell Elected to SOM Faculty Council
- Kearney Is UAB 2013 Distinguished Faculty Lecturer
- Kym Proctor Is Employee of the Month
- Opportunity of a Lifetime UAB President Ray Watts Has Big Vision for the Future of UAB
- UAB Beckman Scholars Attend 2013 Symposium
- Spring Immunology Symposium Brings People Together
- Chaplin Named Associate Dean for Faculty Development
- Mestecky Awarded Honorary Doctorate of Medicine
- Hiramoto Travel Award Deadline July 1, 2013
- Fernandez to Speak at Beckman Symposium