Primary Department Affiliation: Vision Sciences
We use animal models to study the neurobiological mechanism that operates in the developing juvenile eye to match the axial length to the eye’s optical power, producing an eye that is in good focus (emmetropia.) The goal of this research is to learn how emmetropia is normally produced and how the emmetropization mechanism is disrupted to produce myopia or hyperopia in humans. Our main lab tools are real-time PCR and proteomics; immunohistochemistry is an interest. We also (slowly) are developing tree shrews as an animal model of glaucoma because, like primates, they have a load-bearing lamina cribrosa.
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