Study Finds Proof that Immune Defenses Amplify Parkinson's Disease Damage
- Created on June 04, 2013
The same mechanism that lets the immune system mount a massive attack against invading bacteria contributes to the destruction of brain cells as part of Parkinson’s disease, according to a study published online today in the Journal of Neuroscience.
Researchers from the University of Alabama at Birmingham (UAB) found that shutting down production of a key group of immune proteins, major histocompatibility complex II (MHCII), completely protected mice that displayed a “human version” of the disease from related nerve cell death.
The MHCII protein complex enables cells that first respond to infections to display pieces of bacteria or viruses on their surfaces for notice by a second part of the immune system. These displayed pieces of invaders trigger a massive, second wave of immune reactions led by T cells and B cells. While vital to body’s ability to combat infectious disease, full-scale immune responses cause disease-related inflammation and cell death when unleashed in the wrong place. To see the full story click below:
Gift will fund dystonia research at UAB
- Created on May 22, 2013
The University of Alabama at Birmingham has received a $1 million dollar gift from the family of Mrs. Joel E. Johnson, Jr., daughter-in-law of the late Joel E. Johnson, Sr., to enhance and strengthen the dystonia research program at UAB. Dystonia is a neurological movement disorder in which sustained muscle contractions cause twisting and repetitive movements or abnormal postures.
The Joel E. Johnson, Sr., Research Acceleration Fund in Dystonia will support ongoing dystonia research in the Division of Movement Disorders, part of the Department of Neurology.
This gift will help UAB create a world-class research program in dystonia.
Dr. Anne Alexandrov receives top award from AACN
- Created on May 21, 2013
The University of Alabama at Birmingham School of Nursing Professor and Assistant Dean for Program Evaluation Anne Alexandrov, Ph.D., R.N., CCRN, FAAN, will receive the Flame of Excellence Award from the American Association of Critical-Care Nurses (AACN) at its 2013 National Teaching Institute & Critical Care Exposition in Boston, May 18-23, 2013.
AACN's Flame of Excellence Award honors sustained contributions to acute and critical care nursing at a high level and with broad research. Considered the leading international nursing authority on acute stroke management, Alexandrov is a clinical expert in the areas of emergency and critical care nursing, with concentrations in neuroscience and vascular dynamics. In addition to her position with the UAB School of Nursing, Alexandrov has a joint appointment as a professor of neurology at the UAB Comprehensive Stroke Research Center.
Dr. Erik Roberson and Dr. Andy West appointed as Associate Directors of CNET - Center for Neurodegeneration and Experimental Therapeutics
- Created on May 17, 2013
Dr. David Standaert announced this week important changes in the leadership team for the Center for Neurodegeneration and Experimental Therapeutics. Dr. Standaert stated that the Center was created 6 years ago, and has grown impressively. Furthermore, he stated that there are major plans to continue to expand CNET over the next few years, and achieve the Center's primary goal of accelerating progress towards treatments for neurodegenerative disorders.
With current and planned activities, the Center has reached the point where it is necessary to expand the leadership team, therefore, Standaert announced the appointments of Dr. Erik Roberson and Dr. Andy West to Association Directors. Dr. Standaert stated that he hopes in their new roles, they will work to enhance the internal programs and continue the trajectory of growth.
Congratulations Drs. Roberson and West in your new role.
- Dr. William Meador awarded training fellowship from The National MS Society
- Dr. Paula Province will be presenting Neurology Grand Rounds - "Eponymous Neurology: History, Mystery, Mythology"
- Daniel C. Marson, PhD, JD awarded grant funded by the National Endowment for Financial Education (NEFE)
- William F. Sahlie Endowed Lectureship in Epilepsy