University of Alabama at Birmingham researchers have identified a therapeutic target to prevent or delay heart failure from pressure overload of the heart, and a potential biomarker for the same.
Imaging of biomolecules is taking a leap forward at UAB, which installed a $600,000 direct electron detector on its cryo-electron microscope in January. This advanced, direct electron detector will yield near-atomic resolution of macromolecules and 3-D tomography of cells or tissue slices.
UAB ranked 15th nationally among public universities in research expenditures and topped $238 million in NIH funding for FY 2016. The School of Medicine received $186 million of that funding in 2016, with that number expected to top $195 million in 2017.
Human peripheral nerves — all the nerves outside of the central nervous system — are protected by the blood-nerve barrier. Researchers have detailed, for the first time, the normal human transcriptome of the blood-nerve barrier.
In animal experiments, a human-derived glioblastoma significantly regressed when treated with the combination of an experimental enzyme inhibitor and the standard glioblastoma chemotherapy drug, temozolomide.
The AMC21 School of Medicine Research Retreat met on Jan. 19, 2018, with focus on “Strategic Recruitment in the SOM.” As part of the AMC21-five-year goal to reach the top 20 in NIH funding, UAB will need to recruit a net of 80 to 84 funded faculty and retain and develop current faculty.
The School of Medicine is hosting its first Research Roundtable on Tuesday, March 13, 2018, from 7:30 a.m.-4:45 p.m. at the Sheraton Birmingham Hotel. This all-day event will spotlight the School of Medicine’s five research focus areas.
Of the 15 million people living with cancer in the United States in 2016, 62 percent were 65 years or older. A new study from researchers at the University of Alabama at Birmingham sheds light on the factors that affect health-related quality of life in older adults with cancer.
Daniel Gorelick, Ph.D., assistant professor of pharmacology and toxicology at UAB, has created zebrafish mutants in four different receptors that respond to estrogens. He has used the mutants to help unravel a novel mechanism of estrogen action on heart physiology.
Improved production of stem cells is vital if they are to achieve their promise for medical research and disease treatments like transplantation, creating patient-specific cell-replacement therapies to treat neurological diseases, heart ailments, blood diseases and diabetes.
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