What is NF?

Neurofibromatosis (NF) is a term that refers to at least three distinct, hereditary disorders caused by an abnormality in a gene. These disorders include neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2), and schwannomatosis. While NF1 is caused by an alteration, or mutation, in a gene located on chromosome 17, both NF2 and schwannomatosis are caused by mutations in genes located on chromosome 22.

Learn more about the symptoms, diagnosis, causes, and treatment options for each of the three distinct types of neurofibromatosis.

  • Neurofibromatosis type 1 (NF1) is a common inherited neurological disorder affecting about 1 in 3,000 people worldwide. Learn more >
  • Neurofibromatosis type 2 (NF2) affects 1 in 25,000 people and often causes partial or complete hearing loss in both ears. Learn more >
  • Schwannomatosis is a rare form of neurofibromatosis that causes the development of painful tumors on almost any nerve in the body. Learn more >

For more information, please contact the UAB Neurofibromatosis Program at 205-934-4983.