The TReNDD Program at UAB is a collaborative group of investigators applying state of the art biological approaches to understanding human disorders of organogenesis, including elucidating basic mechanisms of organ and tissue development, and normal and disordered responses to injury. Core facilities provide physiologic and molecular analyses to support multiple projects. The laboratories within the TReNDD Program provide training for pre- and postdoctoral trainees in related research. The collaborative environment fosters excellence and facilitates extramural funding through single investigator and multiple investigator projects from a wide range of disciplines.