Director, Division of Radiation Biology
Wallace Tumor Institute
1824 6th Avenue South
Birmingham, Alabama 35233
"My interests are focused on the use of monoclonal antibodies that bind to the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptors for cancer therapy in combination with chemotherapy agents and radiation. The research involves investigation of the mechanisms of enhanced cytotoxicity produced by combination treatment with TRAIL death receptor antibodies and chemoradiation. Orthotopic and metastatic breast and pancreatic cancer xenograft models are being used to optimize therapeutic regimens.
B.S. Carnegie Institute of Technology, Pittsburgh, PA 1967, Physics
M.S. University of Rochester, Rochester, NY 1970, Radiation Biophysics
Ph.D. University of Rochester, Rochester, NY 1972, Biophysics-Immunology
Research Associate, University of Minnesota, 1972-1974
Elected a member of Sigma Xi, 1971
AEC Research Trainee and NIH Trainee in Biophysics, Department of Radiation Biology and Biophysics, University of Rochester, 1969-1972
Radiology Centennial, Inc., Award of Honor, 1995
Elected a member, Board of Directors, Radiopharmaceutical Science Council, Society of Nuclear Medicine, 1998
Avon Foundation Investigator, 2000-2003
John R. Durant Award for Excellence in Cancer Research, UAB Comprehensive Cancer Center Distinguished Faculty Award, 2002.
John Hanephin Award of Research Excellence, John Hanephin Pancreatic Cancer Research Support Fund, 2005
Click on Publications link for a full listing.