Dr. Devin Eckhoff

Professor
Director, Division of Transplantation
Arnold G. Diethelm Chair in Transplantation Surgery

Areas of Interest
pediatric and adult liver transplantation, complex hepatobiliary surgery, ischemia reperfusion injury, xenotransplantation

Biography

Dr. Eckhoff received his undergraduate degree at the University of Michigan in Ann Arbor and his medical diploma from the University of Minnesota. At the University of Wisconsin, he completed a general surgery residency, followed by a transplantation fellowship from 1986-1994. He joined the faculty at the University of Alabama at Birmingham in 1994. In May 2003, he was appointed director of the Division of Transplantation at UAB and in 2004 he became a full professor. Dr. Eckhoff is a member of twenty professional societies including Fellow of American College of Surgeons, American Society of Transplant Surgeons, American Surgical Association and Southern Surgical Association. Dr. Eckhoff serves on a number of councils and committees both for the professional societies as well as internally at UAB. In addition to his title of professor and director of the Division of Transplantation, he has various academic appointments, including medical director of the Alabama Organ Center (AOC), co-director of the UAB Comprehensive Transplant Institute, Arnold G. Diethelm Endowed Chair in Transplantation Surgery and the medical director of transplantation. Dr. Eckhoff is principal investigator on two research projects. He runs an active laboratory in xenotransplant with the desire to transplant genetically modified kidneys from pig models to humans in the near future. Under the progressive direction of Dr. Eckhoff, the transplant program has had significant growth with paired kidney exchange, living related liver donor transplant and various aggressive surgical techniques for tumors including ablation and tumor removal. He has authored, co-authored and collaborated on 132 published manuscripts.


Selected Publications

DuBay DA, MacLennan PA, Reed R.D, Redden D.T., Fouad M, Martin M, Meeks CB, Gray SH, White JA, Eckhoff DE, Locke JE. Medicaid expansion under the affordable care act negatively impacts solid organ transplant outcomes. American Journal of Transplantation.

DuBay DA, MacLennan PA, Reed R.D, Fouad M, Martin M, Meeks CB, Taylor G, Kilgore ML, Tankersley M, Gray SH, White JA, Eckhoff DE, Locke JE. Will proposed changes in liver allocation impact cold ischemia times and transportation costs? American Journal of Transplantation. 2015 Feb 15(2): 541-546, PMID 25612501 (PubMed- in process)

Glueckert LN, Redden DT, Thompson MA, Haque A, Gray SH, Locke J, Eckhoff DE, Fouad M, DuBay DA.  What happens to liver transplant outcomes when the uninsured become insured via the Affordable Care Act? American Journal of Transplant. Submitted 11/12 Manuscript Identification number: AJT-0-12-01583. Accepted Pending Revisions 01/13. (in press

DuBay D, Redden D, Haque A, Gray S, Fouad M, Siminoff L, Holt C, Kohler C, Eckhoff D. Is decedent race an independent predictor of organ donor consent or merely a surrogate marker of socioeconomic status?  Transplantation, 94(8), October 27, 2012.

Lang JD, Teng X, Chumley P, Crawford JH, Isbell S, Chacko BK, Liu Y, Jhala N, Crowe DR, Smith AB, Cross RC, Frenette L, Kelley EE, Wilhite DW, Hall CR, Page GP, Fallon M, Bynon JS, Eckhoff DE,, Patel RP.  Inhaled nitric oxide accelerates restoration of liver function in adults following orthotopic liver transplantation. Journal of Clinical Investigation. 2007 Sep:117(9):2583-91.

Eckhoff DE, Young CJ, Gaston RS, Fineman SW, Deierhoi MH, Foushee MT, Brown RN, Diethelm AG.  Racial disparities in renal allograft survival: Is it a public health issue?  Journal of the American College of Surgeons, 2007May; 204(5): 894-902.

McGuire BM, Julian BA, Bynon JS, Cook WJ, King SJ, Curtis JJ, Accortt NA, Eckhoff DE.  Brief Communication: Glomerulonephritis in patients with hepatitis C cirrhosis undergoing liver transplantation.  Annals of Internal Medicine, May 16, 2006;144(10): 735-741,

Contreras JL, Eckstein C, Smyth CA, Bilbao G, Vilatoba M, Young C, Thompson JA, Fernandez J, Griffith JH, Eckhoff DE.  Activated protein C preserves islet mass after intraportal transplantation:  A novel link between endothelial cell activation, thrombosis, inflammation, and islet cell death.  Diabetes, 53, November 2004.

Eckhoff DE, Eckstein C, Smyth CA, Vilatoba M, Bilbao G, Rahemtulla FG, Young CJ, Thompson JA, Chaudry IH, Contreras JL.  Enhanced isolated pancreatic islet recovery and functionality in rats by 17b-estradiol treatment of brain-death donors.  Surgery, 136(2): 336-345.

Contreras JL, Eckstein C, Smyth CA, Sellers MT, Vilatoba M, Bilbao G, Rahemtulla FG, Young CJ, Thompson AJ, Chaudry IH, Eckhoff DE.  Brain death significantly reduces isolated pancreatic islet yields and functionality in vitro and in vivo after transplantation in rats.  Diabetes, 52(12): 2935-2942, December 2003.

Eckhoff DE, Bilbao G, Frenette L, Thompson JA, Contreras JL.  17b-Protects Liver Against Warm Ischemia/Reperfusion Injury and is associated with increased serum nitric oxide and decreased tumor necrosis factor-alpha.  Surgery, 132(2): 302-309, August 2002.

Eckhoff DE, McGuire B, Sellers M, Contreras J, Frenette L, Young C, Hudson S.  The safety and efficacy of a two dose daclizumab (Zenapax) induction therapy in liver transplant recipients.  Transplantation, 69(9): 1867-1872, May 15, 2000.

Eckhoff DE, McGuire MB, Young CJ, Frenette L, Hudson SL, Contreras J., Bynon JS.  Race - a critical factor in organ donation, patient selection and orthotopic liver transplantation?  Liver Transplantation and Surgery, 4(6): 499-505, November, 1998.

Eckhoff DE, McGuire BM, Frenette LR, Contreras JL, Hudson SL, Bynon JS. Tacrolimus (FK506) and mycophenolate mofetil (MMF) combination therapy versus tacrolimus in adult liver transplantation.  Transplantation, 65(2): 180-187, January 1998.


Education

Medical School
University of Minnesota

Residency
University of Wisconsin - Madison 
General Surgery

Fellowship
University of Wisconsin - Madison 
Transplantation Research Fellow

Fellowship
University of Wisconsin - Madison 
Transplant Clinical and Research Fellow


Contact

Campus Address
Lyons Harrison Research Building
Room 710

Phone
205-975-7622

E-mail
deckhoff@uabmc.edu