Research - News
Diabetic retinopathy is the leading cause of blindness in American adults. The source of this damage may lie in the belly — mainly a leaky small intestine. A novel treatment can possibly prevent or reverse this damage.
The study’s goal is to limit the toxic side effects common to many cancer therapies while not affecting their therapeutic benefits.
Childhood cancer survivors with two genetic variations on the ROBO2 gene and who were treated with high doses of anthracycline treatment have a higher risk of developing cardiomyopathy.
The UALCAN data-mining portal at UAB has been used by cancer clinicians and researchers from more than 100 countries in their search for the molecular basis of cancer.
UAB partners with the Institute of Study Abroad Ireland to create an intentional virtual study abroad experience for students in Alabama.
The spinoff company, IN8bio Inc., uses proprietary drug-resistant immunotherapy licensed in part from UAB. Glioblastoma is the most aggressive type of cancer originating in the brain.
High-resolution knowledge of structure is a key link between viral biology and potential therapeutic use of the virus to quell bacterial infections.
Precision medicine approach may identify those at high genetic risk of hypertension, heart failure, stroke and heart attacks and use precision medicine to help prevent fatal cardiovascular diseases.
This study underscores the vital role of mental health professionals in public health, providing preliminary support for another potential benefit of public health efforts to encourage COVID-19 preventive measures (testing), namely promoting mental health.
The study suggests that BMT survivors were more likely to be unable to afford basic necessities, and to defer medical care, in the wake of the COVID-19 pandemic.
The five-year IPPSE grant will address the critical personnel shortage in education by graduating participants early, making a difference in the lives of P-12 students with disabilities in the Birmingham metro area.
The first large multi-ancestry genetics study of osteoarthritis, or OA, has found 10 novel OA-associated genetic loci, and results showed some of the OA-associated regions are robustly found in every population ancestry studied.
Cardiac intelligence uses artificial intelligence to monitor patients for cardiac disease and progression.
Published findings from UAB suggest that certain firearm laws in one state were associated with other states’ firearm-related deaths. Additionally, permit-to-purchase laws were associated with decreased firearm-related death rates both within a state and nearby states.
The study, utilizing the relatively new field of metagenomics, demonstrated an imbalance in the gut microbiome of patients with Parkinson’s disease.
Insights that are not possible with conventional two-dimensional platforms include characterization of obliterated airways in tuberculosis and hemorrhage from ruptured blood vessels in COVID-19 lungs, at near-microscopic levels.
The AHEAD study is looking to recruit people at risk for developing Alzheimer’s disease for a new study.
UAB researchers have published an article demonstrating how the term “aggressive care,” used loosely by clinicians to describe care that can negatively impact quality of life for patients with serious illness, is often used to inappropriately label the preferences of African American patients.
Experimental neonatal chronic lung disease is marked by a redox imbalance that damages the lungs, and that damage can be ameliorated using a live biotherapeutic mixture of three Lactobacillus species.
Grants totaling more than $3 million have been awarded to UAB researchers in Chemistry and Physics by the Department of Energy, signaling continued investment in UAB projects.
In this cohort study of 19,580 patients with breast cancer, the researchers found that White women who lived in less deprived neighborhoods showed decreased mortality, but that Black women did not.
A UAB study including more than 20,000 ventricular assist device recipients showed that patients diagnosed with familial dilated cardiomyopathy had better clinical outcomes compared with other DCM diagnoses.
This finding suggests utility of treatments before fecal microbial transplants to reduce recipient microbial communities. This would help donor microbial strains dominate in the recipient.
The gift will advance the use of induced pluripotent stem cells as a potential therapy for Alzheimer’s disease.
Experiments reveal that a catalytic subunit of CK2, called CK2α, is an important regulator of mouse CD8+ T cell activation, metabolic reprogramming and differentiation, both in vitro and in a mouse-infection model by the intracellular pathogen Listeria monocytogenes.
At their annual Innovation Awards, UAB’s Bill L. Harbert Institute for Innovation and Entrepreneurship celebrated innovators from all corners of campus for their accomplishments, inventions and ingenuity.
Gould’s helmet research added variables such as fall height and the type of surface struck.
The funding will be used to purchase cutting-edge equipment to assist with high-containment research productivity and pandemic preparedness at UAB.
Insights gained from this project can lead to a new understanding of the mechanisms by which human deep-brain activity gives rise to cognitive-emotional behaviors, such as social thought processes, impulsivity and affect.
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