Displaying items by tag: research

At UAB, the company IN8bio Inc. is running a Phase I clinical trial to treat glioblastoma multiforme, the most aggressive type of cancer that originates in the brain.

The PPMI study is looking for biomarkers for Parkinson’s disease, which would help identify those at risk and track the progression of the disease.

Recent studies have shown that formal exercise training can help boost memory, and memory deficit is relatively common in people with epilepsy.

Basic and translational research in this field aims to repair heart injury and prevent the heart failure that often follows a heart attack.

Bacteria use molecular machines to move proteins, including toxins, across cell membranes. M. tuberculosis, which kills more than 1 million people a year, uses the ESX-4 type VII secretion system to transports its potent exotoxin.

The largest registry of U.S. children with cancer who were diagnosed with COVID-19 found an increased risk of having severe infection and having their cancer therapy modified because of COVID, underscoring the urgency of vaccinations for these children, the authors say.

The Hugh Kaul Precision Medicine Institute will help build the interface of the Biomedical Data Translator, a “virtual brain” that will host all biomedical data in the world. 

Young cancer survivors are at higher risk of developing subsequent HPV-related cancers than the general population, but less likely to receive the HPV vaccine. Findings from the first clinical trial of its kind support making HPV vaccination a routine part of oncologic care for all young cancer survivors, researchers say.

A study conducted by UAB researchers found that using genetic information for choosing medical treatment after getting a heart stent reduces the risk of potentially fatal cardiovascular events.
Preclinical experiments show how to identify non-responding tumors and improve their response to immunotherapy, using two investigational new drugs that are permitted for human use. Physicians could immediately start investigational research in patients to test the effectiveness of this personalized approach.
The grant links researchers from different disciplines, institutions and locations to study basic mechanisms that contribute to Parkinson’s disease.

Release of TT-10 from nanoparticles improved heart function after a heart attack, accompanied by increased cardiomyocyte proliferation and smaller infarct size.

UAB researchers will study psilocybin, a psychedelic compound, on its effects on smoking cessation.     
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