Jeff Hansen

Jeff Hansen

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Research Editor

jeffhans@uab.edu • (205) 209-2355

Communicates UAB research discoveries and initiatives from across the university for a variety of audiences.

Specific beats include: biochemistry; cell, developmental and integrated biology; microbiology; molecular genetics; neurobiology; pathology; pharmacology and tocixology; Alabama Drug Discovery Alliance; Bill L. Harbert Institute for Innovation and Entrepreneurship.

The spinoff company, IN8bio Inc., uses proprietary drug-resistant immunotherapy licensed in part from UAB. Glioblastoma is the most aggressive type of cancer originating in the brain.
High-resolution knowledge of structure is a key link between viral biology and potential therapeutic use of the virus to quell bacterial infections.
The first large multi-ancestry genetics study of osteoarthritis, or OA, has found 10 novel OA-associated genetic loci, and results showed some of the OA-associated regions are robustly found in every population ancestry studied.
Insights that are not possible with conventional two-dimensional platforms include characterization of obliterated airways in tuberculosis and hemorrhage from ruptured blood vessels in COVID-19 lungs, at near-microscopic levels.
Experimental neonatal chronic lung disease is marked by a redox imbalance that damages the lungs, and that damage can be ameliorated using a live biotherapeutic mixture of three Lactobacillus species.
This finding suggests utility of treatments before fecal microbial transplants to reduce recipient microbial communities. This would help donor microbial strains dominate in the recipient.
Experiments reveal that a catalytic subunit of CK2, called CK2α, is an important regulator of mouse CD8+ T cell activation, metabolic reprogramming and differentiation, both in vitro and in a mouse-infection model by the intracellular pathogen Listeria monocytogenes.
Direct reprogramming is a potential therapy for heart attack patients. In vitro, TBX20 improved contractility and mitochondrial function of reprogrammed heart muscle cells.
Diseases linked to atherosclerosis are the leading cause of death in the United States.
This novel finding will help guide successful therapeutic design and strategies for acute kidney injury and chronic kidney disease.
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