The O’Neal Comprehensive Cancer Center recently awarded six projects a total of $960,000 in research grants through its O’Neal Invests program. O’Neal Invests supports nascent, paradigm-shifting cancer research proposed by O’Neal Cancer Center investigators. These are novel ideas with considerable promise and potential impact in the field of cancer care, as determined by a peer-reviewed panel of experts.

The O’Neal Invests program provides UAB investigators with two years of funding for new cancer-related projects allow these investigators to generate preliminary data that can support competitive applications for R01 grants from the National Cancer Institute. Each grant provides $80,000 in funding per year, and each project may include one or more co- investigators.

The O’Neal Cancer Center requests applications for this program twice per year, once in the spring and once in the fall. O’Neal Cancer Center membership is not a requirement to apply, but awardees must become members.

Applicants who are not awarded funding receive feedback on their proposals from the review panel and are encouraged to reapply.

By donating to the O’Neal Invests program, you can help support cancer research at the O’Neal Cancer Center. To give to O’Neal Invests, contact Lisa Roth at This email address is being protected from spambots. You need JavaScript enabled to view it. or (205) 934-0930.

Spring 2021 O'Neal Invests Awardees

  • Christopher Klug, Ph.D., and Jeremy Foote, Ph.D.

    Department
    Department of Microbiology

    Project Title
    “Defining the Anti-Tumor Role of Antibody in Suppression of Pancreatic Ductal Adenocarcinoma”

    Disease
    Pancreatic Cancer

  • Margaret Liang, M.D., M.S., and Maria Pisu, Ph.D.

    Departments

    Margaret Liang, M.D., M.S.
    Department of Obstetrics & Gynecology

    Maria Pisu, Ph.D.
    Department of Medicine

    Project Title
    “Proactive Costs of Care Interventions to Decrease Financial Toxicity in Cancer Patients”

    Diseases
    Gynecologic Cancer and Breast Cancer

  • Rui Lu, Ph.D.

    Department
    Department of Medicine

    Project Title
    “The Role of PHF15 in MLL-r Leukemia and Therapeutic Response”

    Disease
    Leukemia

  • Jamil Saad, Ph.D., and Yabing Chen, Ph.D.

    Departments

    Jamil Saad, Ph.D.
    Department of Microbiology

    Yabing Chen, Ph.D.
    Department of Pathology

    Project Title
    “Structural Basis for Fas-Mediated Apoptosis and Mechanisms of Inhibition in Breast Cancer”

    Disease
    Breast Cancer

  • Rajeev Samant, Ph.D.

    Department
    Department of Pathology

    Project Title
    “Characterization of Hypoxia-Specific Adaption of Ribosomes”

    Disease
    Breast Cancer

  • Lizhong Wang, M.D., Ph.D.

    Department
    Department of Genetics

    Project Title
    “CRISPR-Perturbation Single-Cell Platform to Dissect the Tumor-Immune Interaction and Metastasis”

    Disease
    Breast Cancer

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