Mentor: Ichiro Nakano, MD, PhD, Professor, Department of Neurosurgery, co-Director of Brain SPORE, Director for Office of Laboratory Research, University of Alabama at Birmingham, Birmingham, AL, ichiro@uab.edu


We are seeking 2 postdoctoral fellows to participate in an NIH-funded study of molecular mechanisms and therapy development for brain cancers targeting their stem cells. The primary role of the position will be to perform experiments with patient-derived cancer stem cells and their xenograft models in mouse brains. In addition, the fellow can work on developmental therapeutics with the existing collaborators in various scientific fields. The fellow will have responsibility for all aspects of the project from data collection and analysis to preparation of scientific publications. No specific prior experience is needed but those who seek for academic independent career are welcome. Candidates should have a Ph.D. or equivalent. The appoiment is set for 6 months, followed by annual renewal in case of mutual agreement. Salary is commensurate with experience and NIH guidelines. Our laboratory has an established track record in the field of brain cancer and cancer stem cells as demonstrated by our recent publications in well-respected journals (Mao et al., PNAS 2013; Bhat et al., Cancer Cell 2013; Kim et al., Stem Cell Reports 2015; Cheng et al., Stem Cell Reports 2015; Kim et al., Cell Death & Diff 2015) Below is the current funding for this lab:

P01 CA163205, PI: Caligiuri, M; Chiocca EA (Role: Core PI)
Priority Score:11 2/7/2013-1/31/2018
Circumventing Barriers to Effective Oncolytic Virotherapy of Malignant Gliomas

R01 NS083767, PI: Nakano, I (Contact); Lee, J
Priority Score: 23, Percentile: 5.0 7/1/2013-6/30/2018
Targeting MELK-mediated EZH2 signaling in Glioma Stem Cells

R01 NS083629, PI: Lathia (Role: Co-Investigator)
Percentile: 21 7/1/2013-6/30/2018
Novel adhesion mechanisms in glioblastoma stem cells.

R21CA175875, PI: Nakano, I (Contact); Penalva, L
Priority Score: 18, Percentile: 4.0 1/1/2014-12/31/2015
Determination of Musashi1/CD44v6 signaling in mesenchymal glioma stem cells.

R01NS087913, PI: Nakano, I; Rich, J (Contact)
Priority Score: 21, Percentile: 8 4/15/2014-2/28/2019
Metabolism Informs Intertumoral & Intratumoral Heterogeneity

R01CA183991, PI: Nakano, I
Priority score: 20, Percentile: 10.0 2/15/2015-1/31/2020
Novel role of compensatory proliferation in human brain tumor.

R21CA192042, PI: Verbridge, S (Role: Co-investigator)
Priority score: 20, Percentile: 6.0 2/15/2015-1/31/2017
Targeting electric field therapy for malignant infiltrative glioma

R01CA201402, PI: Nakano, I; Cerione, RA (Contact)
Priority score: 19, Percentile: 5.0 Pending
The roles of a unique GTP-binding protein/crosslinking enzyme in disease

R01 NS093843-01, PI: Cheng SY (Role: Co-Investigator)
Priority score: 19, Percentile: 4.0 Pending
Glioblastoma Subtype Interconversion Through miRNA Control of Wnt Signaling

The University of Alabama at Birmingham (UAB) is one of America’s premier research universities, ranking among the top 25 in funding from the National Institutes of Health. UAB is consistently ranked as one of the top places for post-doctoral studies in the country. It has an office of Postdoctoral education that offers many career training opportunities (http://www.uab.edu/postdocs), and has a vibrant neuroscience community (http://www.uab.edu/medicine/cnc).

Interested candidates should forward a cover letter, CV, and names of 3 references to:

Dr. Ichiro Nakano
Professor, Department of Neurosurgery
ichiro@uab.edu
 

Postdoc Awards and Benefits 

Competitive postdoc awards are available including internships, grant incentives, funds to enhance education and collaboration outside UAB, and teaching opportunities at local universities. There is also a Postdoc Research Day with monetary awards. The OPE strongly encourages UAB research mentors to follow the National Research Service Award stipend level guidelines, and postdoctoral scholars qualify for health, life, and other insurances. They also have the right to participate in the university’s 403(b) program and enjoy vacation, sick leave, maternity/paternity leave, and other benefits.