Mentor:  Dr. Steven M. Rowe, Professor, Division of Pulmonary, Allergy and Critical Care, University of Alabama at Birmingham, 706 MCLM, 1918 Univeristy Blvd., Birmingham, AL 35294. Telephone: (205) 934-9640; Email: smrowe@uab.edu

Multiplepostdoctoral fellow positions are open to study cystic fibrosis, COPD, and disorders of mucus clearance. Of particular interest is the modulation of CFTR for the treatment of CF and other airways diseases, and the role of ion transport in the regulation of mucus clearance in CF and other diseases where CFTR dysregulation plays a pathogenic role, including smoking related lung disease. Please refer to our publications (Birket et al., Amer J Resp Crit Care Med 2014;190(4):421; Raju et al., Amer J Resp Crit Care Med 2013;188(11):1321; Xue et al, Amer J Resp Cell Mol Biol 2013; Rowe et al, Am J Respir Crit Care Med 2014;190(2):175; and Tuggle et al, PLoS One. 2014 Mar 7:9(3):e91253). Primary projects available include (1) the screening and secondary characterization of novel agents that induce translational readthrough of premature termination codons in CFTR using electrophysiologic and other techniques, in vitro and in vivo; (2) the development of an optical imaging technology (micro-optical coherence tomography) as a high-throughput screening device in cell culture and an in vivo tool for the evaluation of mucociliary clearance; and (3) characterization of acquired CFTR dysfunction in animal models of smoking related lung disease. The applicant will have opportunity to develop multiple projects using cell culture and animal models in a well funded (NIH, CFF) research laboratory. The individual should have experience designing, interpreting, and performing experiments using physiologic measures of ion transport and/or imaging; management of animal models; and/or standard molecular biology techniques. Prior experience in high throughput screening and/or biomedical optics or engineering is highly valued. The position requires performing and designing experiments with minimal input from the mentor, writing manuscripts for publication and presentation, and a high level of self-motivation. The successful candidate must be innovative and interested in pursuing an independent research effort upon successful completion of the fellowship. Ph.D. and/or M.D. degree required. Applicants should submit their CV and the names and contact information of three references to Steven M. Rowe, M.D., M.S.P.H., Professor, University of Alabama at Birmingham, 706 MCLM, 1918 University Blvd, Birmingham, Alabama 35294, Tel: 205-934-9640, Fax: 205-934-7593, E-mail: smrowe@uab.edu

The University of Alabama at Birmingham is an Affirmative Action/Equal Opportunity Employer and welcomes applications from qualified women and minorities. 

Postdoc Awards and Benefits 

Competitive postdoc awards are available including internships, grant incentives, funds to enhance education and collaboration outside UAB, and teaching opportunities at local universities. There is also a Postdoc Research Day with monetary awards.

The OPE strongly encourages UAB research mentors to follow the National Research Service Award stipend level guidelines, and postdoctoral scholars qualify for health, life, and other insurances. They also have the right to participate in the university‚Äôs 403(b) program and enjoy vacation, sick leave, maternity/paternity leave, and other benefits.