Mentor: Dr. Karin Hardiman opens a new website, Department of Surgery

The Hardiman Lab in the Gastrointestinal Surgery Division of the Department of Surgery at the University of Alabama at Birmingham seeks a full-time postdoctoral research associate to join our NIH funded research laboratory.  Our research group has recently been awarded a NIH grant to investigate the importance of ST6Gal1 in rectal cancer therapeutic resistance.

ST6Gal1, an enzyme responsible for sialylation of N-glycans on select glycoproteins, is found in several cancers including ovarian, pancreatic, and colorectal cancers. We have found that altered glycosylation is found in rectal cancer patients with poor treatment response. We are interested in understanding and abrogating resistance due to this enzyme as well as resistance due to other mechanisms.

Principle responsibilities of this position include design and perform experiments, analyze, interpret and discuss data with PI, assist other lab members and projects; applying for postdoctoral funding opportunities; write and submit manuscripts; and present at national or international meetings.


Preferred qualifications include a PhD or MD/PhD in cell biology, molecular biology or in a biomedical science related field. Basic laboratory experience is required with cell culture, rodent handling, cell and tissue imaging/microscopy, immunoblotting and qRT-PCR. Experience with flow cytometry, organoid models, high-resolution microscopy, and/or RNA-seq experience is considered a strength. The candidate will be required to work with a high degree of independence and as part of a team. Excellent communication skills with a record of successful independent research are also required.

How to apply:

Full time appointment is for 12 months, with renewal based on performance and funding availability. Interested individuals should include a 1–2-page cover letter describing their research experience and interests along with a CV and three references to Dr. Karin Hardiman, This email address is being protected from spambots. You need JavaScript enabled to view it..

About our Postdoc Office

UAB is committed to the development and success of outstanding postdoctoral scientists. Here at UAB, nearly 300 postdoctoral fellows are training currently in a variety of disciplines. Competitive postdoc awards are available including internships, grant incentives, funds to enhance education and collaboration outside UAB, and teaching opportunities at local universities. There is also a Postdoc Research Day with monetary awards. The Office of Postdoctoral Education strongly encourages UAB research mentors to follow the National Research Service Award stipend level guidelines, and postdoctoral scholars qualify for health, life, and other insurances. They also have the right to participate in the university’s 403(b) program and enjoy vacation, sick leave, maternity/paternity leave, and other benefits.

About the University

The University of Alabama at Birmingham (UAB) is a research university and academic health center that discovers, teaches, and applies knowledge for the intellectual, cultural, social, and economic benefit of Birmingham, the state, and beyond. UAB is internationally renowned for its intensely collaborative culture that has — for more than five decades — produced breakthroughs in education, health care, research, and service. UAB was ranked #1 in the United States, and in the top 10 worldwide, in the Times Higher Education World University Rankings, 2018 Young University Rankings.

Spanning more than 100 city blocks, UAB is the state of Alabama’s largest single employer with over 26,000 employees and has an annual state-wide economic impact exceeding $7.15 billion. U.S. News & World Report’s 2020 “America’s Best Graduate Schools” ranks 14 UAB graduate programs among the nation’s top 25 and 10 UAB specialties were ranked among the nation’s top 50 in the magazine’s 2018-2019 Best Hospitals report. UAB research grants and awards are at a record high, exceeding $527 million in FY18, including $320 million in NIH funding for FY18. UAB ranks 31st among all universities in federal research funding and 15th among public universities. UAB's NIH funding continues to grow among peer institutions in the Southeast and beyond, with the university ranking 20th among all universities in NIH funding and eighth among public universities. The UAB Heersink School of Medicine is ranked 21st among medical schools in NIH funding and eighth among public medical schools.

UAB is an Equal Opportunity/Affirmative Action Employer committed to fostering a diverse, equitable and family-friendly environment in which all faculty and staff can excel and achieve work/life balance irrespective of, race, national origin, age, genetic or family medical history, gender, faith, gender identity, and expression as well as sexual orientation. UAB also encourages applications from individuals with disabilities and veterans.

For more information on Equal Opportunity and Affirmative Action at UAB, visit the UAB Office of Diversity, Equity and Inclusion opens a new website, call (205) 934-8762, or contact the office at 701 20th Street South, AB 336, Birmingham, AL 35294-0103.