Annual Workshop on Metabolomics

The 6th Annual Workshop on Metabolomics was held July 22-27, 2018 on the campus of the University of Alabama at Birmingham.

The course has been jointly sponsored by the National Institute of General Medical Sciences (NIGMS) as part of the NIH Common Fund Metabolomics Initiative, and the Departments of Chemistry and Pharmacology and Toxicology at UAB.

Details on the workshop can be found on the Metabolomics Workshop web page.

Barnes elevated to Distinguished Professor

UAB Reporter
July 30, 2018

The University of Alabama System Board of Trustees awarded the rank of Distinguished Professor to five faculty during its meeting June 8.

Steve Barnes

Stephen Barnes, Ph.D., was named Distinguished Professor of Pharmacology and Toxicology in the School of Medicine. Barnes came to UAB in 1977 as a mathematical gastroenterology fellow through the National Library of Medicine and joined the faculty in 1979 as an assistant professor. Now, in addition to his position in the Department of Pharmacology and Toxicology, Barnes is a senior scientist at UAB’s Center for Free Radical Biology, Nutrition Obesity Research Center, Center for Bone and Joint Disease and Nephrology Research and Training Center and he has dual appointments in the departments of Environmental Health Sciences, Genetics and Vision Sciences.

Barnes has published more than 300 peer-reviewed journal articles, reviews and book chapters and has delivered lectures at institutions such as Vanderbilt University, Johns Hopkins University and the University of Durham in in Durham, England. In 2012, Barnes was named UAB’s Distinguished Faculty Lecturer. He also is a member of the International Science Advisory Panel at Imperial College London’s National Phenome Center.

Recent publications from TMPL

The ApoA-I Mimetic Peptide 4F Protects Apolipoprotein A-I From Oxidative Damage.
White CR, Datta G, Wilson L, Palgunachari MN, Anantharamaiah GM.
Chem Phys Lipids. 2019 Jan 29. pii: S0009-3084(18)30185-3. [doi: 10.1016/j.chemphyslip.2019.01.009] [Epub ahead of print] [PMID: 30707910]

Vaporized E-Cigarette Liquids Induce Ion Transport Dysfunction in Airway Epithelia.
Lin VY, Fain MD, Jackson PL, Berryhill TF, Wilson LS, Mazur M, Barnes SJ, Blalock JE, Raju SV, Rowe SM.
Am J Respir Cell Mol Biol. 2018 Dec 21. [doi: 10.1165/rcmb.2017-0432OC] [Epub ahead of print] [PMID: 30576219]

Truncating PKHD1 and PKD2 mutations alter energy metabolism.
Chumley P, Zhou J, Mrug S, Chacko BK, Parant JM, Challa AK, Wilson LS, Berryhill TF, Barnes S, Kesterson RA, Bell PD, Darley-Usmar VM, Yoder BK, Mrug M.
Am J Physiol Renal Physiol. 2018 Dec 19. [doi: 10.1152/ajprenal.00167.2018] [Epub ahead of print] [PMID: 30566001]

More Publications

About TMPL

The Targeted Metabolomics and Proteomics Laboratory (TMPL) is organized to provide a variety of analytical and technical services using mass spectrometry to UAB investigators. The laboratory has three mass spectrometers, a triple quadrupole instrument (SCIEX 4000), a quadrupole-linear ion trap instrument (SCIEX 6500 Qtrap), and quadrupole-TOF (SCIEX 5600 TripleTOF). The SCIEX 5600 TripleTOF is particularly powerful for comprehensive and targeted proteomics, lipidomics and metabolomics. The combination of Eksigent microflow 200 LC and 415 nanoLC with the mass spectrometers provides the highest possible sensitivity for sample analysis. The SCIEX 6500 Qtrap is fitted with a SelexION™ interface for ion mobility studies.

Contact Dr. Matt Renfrow about use of hi-resolution Orbitrap Velos instrument (renfrow@uab.edu; 205 996-4681).

A Bruker MALDI TOF-TOF instrument is available in the Comprehensive Cancer Center Core Laboratory of Dr. Jim Mobley (mobleyja@uab.edu; 205 996-6363).

New sample and data-handling arrangements in TMPL – investigators please note



MRM
Figure from J Chromatogr B Analyt
Technol Biomed Life Sci.
[ PMID: 20346741]
MRMPath
MRMPath